Pathogenesis of follicular lymphoma

Mesenchymal stromal cells orchestrate follicular lymphoma cell niche through the CCL2-dependent recruitment and polarization of monocytes

(2012) F. Guilloton et al.   BLOOD

IL-12 upregulates TIM-3 expression and induces T cell exhaustion in patients with follicular B cell non-Hodgkin lymphoma

(2012) Zhi-Zhang Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

(2012) J. G. Lohr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Newly diagnosed and relapsed follicular lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2011) M. Dreyling et al.   ANNALS OF ONCOLOGY

Follicular lymphoma grade 3B

(2011) Itziar Salaverria et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

New agents in follicular lymphoma

(2011) Bruce D. Cheson   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Transformation of follicular lymphoma

(2011) Izidore S. Lossos et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Distribution, function, and prognostic value of cytotoxic T lymphocytes in follicular lymphoma: a 3-D tissue-imaging study

(2011) C. Laurent et al.   BLOOD

Follicular lymphoma in situ: clinical implications and comparisons with partial involvement by follicular lymphoma

(2011) A. G. Jegalian et al.   BLOOD

The Eph-Receptor A7 Is a Soluble Tumor Suppressor for Follicular Lymphoma

(2011) Elisa Oricchio et al.   CELL

Active and Passive Immunotherapy for Lymphoma: Proving Principles and Improving Results

(2011) Joshua Brody et al.   JOURNAL OF CLINICAL ONCOLOGY

Rituximab Maintenance for the Treatment of Patients With Follicular Lymphoma: An Updated Systematic Review and Meta-analysis of Randomized Trials

(2011) Liat Vidal et al.   JNCI-Journal of the National Cancer Institute

High rate of TNFRSF14 gene alterations related to 1p36 region in de novo follicular lymphoma and impact on prognosis

(2011) E Launay et al.   LEUKEMIA

BCL2 mutations in diffuse large B-cell lymphoma

(2011) J M Schuetz et al.   LEUKEMIA

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

(2011) Laura Pasqualucci et al.   NATURE

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

(2011) Ryan D. Morin et al.   NATURE

Analysis of the coding genome of diffuse large B-cell lymphoma

(2011) Laura Pasqualucci et al.   NATURE GENETICS

Molecular Ontogeny of Donor-Derived Follicular Lymphomas Occurring after Hematopoietic Cell Transplantation

(2011) Oliver Weigert et al.   Cancer Discovery

EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis

(2010) I. Velichutina et al.   BLOOD

Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

(2010) D. B. Yap et al.   BLOOD

Increased angiogenic sprouting in poor prognosis FL is associated with elevated numbers of CD163+ macrophages within the immediate sprouting microenvironment

(2010) A. J. Clear et al.   BLOOD

Acquired TNFRSF14 Mutations in Follicular Lymphoma Are Associated with Worse Prognosis

(2010) K.-J. J. Cheung et al.   CANCER RESEARCH

A Unifying Microenvironment Model in Follicular Lymphoma: Outcome Is Predicted by Programmed Death-1-Positive, Regulatory, Cytotoxic, and Helper T Cells and Macrophages

(2010) B. E. Wahlin et al.   CLINICAL CANCER RESEARCH

Vascularization predicts overall survival and risk of transformation in follicular lymphoma

(2010) P. Farinha et al.   HAEMATOLOGICA

Ig gene diversification and selection in follicular lymphoma, diffuse large B cell lymphoma and primary central nervous system lymphoma revealed by lineage tree and mutation analyses

(2010) N. S. Zuckerman et al.   INTERNATIONAL IMMUNOLOGY

Rituximab Maintenance Treatment of Relapsed/Resistant Follicular Non-Hodgkin's Lymphoma: Long-Term Outcome of the EORTC 20981 Phase III Randomized Intergroup Study

(2010) Marinus H.J. van Oers et al.   JOURNAL OF CLINICAL ONCOLOGY

Rituximab maintenance for 2 years in patients with high tumour burden follicular lymphoma responding to rituximab plus chemotherapy (PRIMA): a phase 3, randomised controlled trial

(2010) Gilles Salles et al.   LANCET

Follicular lymphoma cell niche: identification of a preeminent IL-4-dependent TFH–B cell axis

(2010) C Pangault et al.   LEUKEMIA

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

(2010) Ryan D Morin et al.   NATURE GENETICS

Glycosylation of surface Ig creates a functional bridge between human follicular lymphoma and microenvironmental lectins

(2010) V. Coelho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

(2010) C. J. Sneeringer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression

(2010) J. M. Irish et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prognostic value of regulatory T cells, lymphoma-associated macrophages, and MUM-1 expression in follicular lymphoma treated before and after the introduction of monoclonal antibody therapy: a Southwest Oncology Group Study

(2009) J. W. Sweetenham et al.   ANNALS OF ONCOLOGY

Transformation of follicular lymphoma to diffuse large B-cell lymphoma may occur by divergent evolution from a common progenitor cell or by direct evolution from the follicular lymphoma clone

(2009) E. Carlotti et al.   BLOOD

A pluripotency signature predicts histologic transformation and influences survival in follicular lymphoma patients

(2009) A. J. Gentles et al.   BLOOD

Follicular lymphoma cells induce T-cell immunologic synapse dysfunction that can be repaired with lenalidomide: implications for the tumor microenvironment and immunotherapy

(2009) A. G. Ramsay et al.   BLOOD

The architectural pattern of FOXP3-positive T cells in follicular lymphoma is an independent predictor of survival and histologic transformation

(2009) P. Farinha et al.   BLOOD

Lymphomas with concurrent BCL2 and MYC translocations: the critical factors associated with survival

(2009) N. A. Johnson et al.   BLOOD

The microenvironment in mature B-cell malignancies: a target for new treatment strategies

(2009) J. A. Burger et al.   BLOOD

TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas

(2009) K. Honma et al.   BLOOD

High Numbers of Tumor-Infiltrating Programmed Cell Death 1–Positive Regulatory Lymphocytes Are Associated With Improved Overall Survival in Follicular Lymphoma

(2009) Joaquim Carreras et al.   JOURNAL OF CLINICAL ONCOLOGY

Frequent inactivation of A20 in B-cell lymphomas

(2009) Motohiro Kato et al.   NATURE

S  mutation patterns suggest different progression pathways in follicular lymphoma: early direct or late from FL progenitor cells

(2008) P. Ruminy et al.   BLOOD

Prognostic influence of tumor-infiltrating mast cells in patients with follicular lymphoma treated with rituximab and CHOP

(2008) M. Taskinen et al.   BLOOD

Genome-wide profiling of follicular lymphoma by array comparative genomic hybridization reveals prognostically significant DNA copy number imbalances

(2008) K.-J. J. Cheung et al.   BLOOD

Human Chromosomal Translocations at CpG Sites and a Theoretical Basis for Their Lineage and Stage Specificity

(2008) Albert G. Tsai et al.   CELL

Prognostic significance of secondary cytogenetic alterations in follicular lymphomas

(2008) Nathalie A. Johnson et al.   GENES CHROMOSOMES & CANCER

Microarray-based genomic profiling reveals novel genomic aberrations in follicular lymphoma which associate with patient survival and gene expression status

(2008) Carsten Schwaenen et al.   GENES CHROMOSOMES & CANCER

Impact of the tumor microenvironment on prognosis in follicular lymphoma is dependent on specific treatment protocols

(2008) D. de Jong et al.   HAEMATOLOGICA

Follicular lymphoma B cells induce the conversion of conventional CD4+T cells to T-regulatory cells

(2008) Weiyun Z. Ai et al.   INTERNATIONAL JOURNAL OF CANCER

Prevalence and frequency of circulating t(14;18)-MBR translocation carrying cells in healthy individuals

(2008) Frank Schüler et al.   INTERNATIONAL JOURNAL OF CANCER

Phase III Trial of Consolidation Therapy With Yttrium-90–Ibritumomab Tiuxetan Compared With No Additional Therapy After First Remission in Advanced Follicular Lymphoma

(2008) Franck Morschhauser et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase III Study of R-CVP Compared With Cyclophosphamide, Vincristine, and Prednisone Alone in Patients With Previously Untreated Advanced Follicular Lymphoma

(2008) Robert Marcus et al.   JOURNAL OF CLINICAL ONCOLOGY

Population-Based Analysis of Incidence and Outcome of Transformed Non-Hodgkin's Lymphoma

(2008) Abdulwahab J. Al-Tourah et al.   JOURNAL OF CLINICAL ONCOLOGY

High Numbers of Tumor-Associated Macrophages Have an Adverse Prognostic Value That Can Be Circumvented by Rituximab in Patients With Follicular Lymphoma Enrolled Onto the GELA-GOELAMS FL-2000 Trial

(2007) Danielle Canioni et al.   JOURNAL OF CLINICAL ONCOLOGY