Identification of a new dysfunctional platelet P2Y12 receptor variant associated with bleeding diathesis

A novel mutation in the P2Y12receptor and a function-reducing polymorphism in protease-activated receptor 1 in a patient with chronic bleeding

(2014) Y. M. Patel et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Agonist-bound structure of the human P2Y12 receptor

(2014) Jin Zhang et al.   NATURE

Structure of the human P2Y12 receptor in complex with an antithrombotic drug

(2014) Kaihua Zhang et al.   NATURE

Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments

(2013) G. Madhavi Sastry et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Recommendations for the standardization of light transmission aggregometry: a consensus of the working party from the platelet physiology subcommittee of SSC/ISTH

(2013) M. Cattaneo et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Congenital defects of platelet function

(2012) Gianmarco Podda et al.   PLATELETS

The platelet P2Y12 receptor under normal and pathological conditions. Assessment with the radiolabeled selective antagonist [3H]PSB-0413

(2012) Philippe Ohlmann et al.   Purinergic Signalling

An intact PDZ motif is essential for correct P2Y12 purinoceptor traffic in human platelets

(2011) S. Nisar et al.   BLOOD

Comparison of different procedures to prepare platelet-rich plasma for studies of platelet aggregation by light transmission aggregometry

(2011) Eti Alessandra Femia et al.   PLATELETS

Molecular defects of the platelet P2 receptors

(2011) Marco Cattaneo   Purinergic Signalling

Bleeding manifestations of congenital and drug-induced defects of the platelet P2Y12 receptor for adenosine diphosphate

(2011) Marco Cattaneo   THROMBOSIS AND HAEMOSTASIS

The platelet P2Y12 receptor for adenosine diphosphate: congenital and drug-induced defects

(2010) M. Cattaneo   BLOOD

New P2Y 12 Inhibitors

(2010) Marco Cattaneo   CIRCULATION

Usefulness of a flow cytometric analysis of intraplatelet vasodilator-stimulated phosphoprotein phosphorylation for the detection of patients with genetic defects of the platelet P2Y12 receptor for ADP

(2010) M. L. ZIGHETTI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Identification and characterization of a novel P2Y12 variant in a patient diagnosed with type 1 von Willebrand disease in the European MCMDM-1VWD study

(2009) M. E. Daly et al.   BLOOD

Haploinsufficiency of the platelet P2Y12 gene in a family with congenital bleeding diathesis

(2009) G. Fontana et al.   HAEMATOLOGICA

Interaction of the active metabolite of prasugrel, R-138727, with cysteine 97 and cysteine 175 of the human P2Y12receptor

(2008) I. ALGAIER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS