-Catenin activation synergizes with Pten loss and Myc overexpression in Notch-independent T-ALL

The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia

(2012) L. Zuurbier et al.   HAEMATOLOGICA

The TCF-1 and LEF-1 Transcription Factors Have Cooperative and Opposing Roles in T Cell Development and Malignancy

(2012) Shuyang Yu et al.   IMMUNITY

The molecular basis of T cell acute lymphoblastic leukemia

(2012) Pieter Van Vlierberghe et al.   JOURNAL OF CLINICAL INVESTIGATION

Notch1 counteracts WNT/β-catenin signaling through chromatin modification in colorectal cancer

(2012) Hyun-A Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Clinical Impact ofNOTCH1and/orFBXW7Mutations,FLASHDeletion, andTCRStatus in Pediatric T-Cell Lymphoblastic Lymphoma

(2012) Celine Callens et al.   JOURNAL OF CLINICAL ONCOLOGY

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

(2012) Jinghui Zhang et al.   NATURE

The Nuclear Effector of Wnt-Signaling, Tcf1, Functions as a T-Cell–Specific Tumor Suppressor for Development of Lymphomas

(2012) Machteld M. Tiemessen et al.   PLOS BIOLOGY

Posttranscriptional deregulation of MYC via PTEN constitutes a major alternative pathway of MYC activation in T-cell acute lymphoblastic leukemia

(2011) M. Bonnet et al.   BLOOD

Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia

(2011) Irene Homminga et al.   CANCER CELL

Canonical Wnt Signaling Regulates Hematopoiesis in a Dosage-Dependent Fashion

(2011) Tiago C. Luis et al.   Cell Stem Cell

Suppression of leukemia development caused by PTEN loss

(2011) W. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia

(2010) Maddalena Paganin et al.   BLOOD REVIEWS

Proliferation and bone marrow engraftment of AML blasts is dependent on β-catenin signalling

(2010) Elena K. Siapati et al.   BRITISH JOURNAL OF HAEMATOLOGY

Deletion of the WNT Target and Cancer Stem Cell Marker CD44 in Apc(Min/+) Mice Attenuates Intestinal Tumorigenesis

(2008) J. Zeilstra et al.   CANCER RESEARCH

Canonical Notch Signaling Is Dispensable for the Maintenance of Adult Hematopoietic Stem Cells

(2008) Ivan Maillard et al.   Cell Stem Cell

CD44 and EpCAM: Cancer-Initiating Cell Markers

(2008) Rachid Marhaba et al.   CURRENT MOLECULAR MEDICINE

ICAT expression disrupts  -catenin-TCF interactions and impairs survival of thymocytes and activated mature T cells

(2008) M. Z. Hossain et al.   INTERNATIONAL IMMUNOLOGY

Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1

(2008) Xiaoyu Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation

(2008) Wei Guo et al.   NATURE