Characterization of the TGF- 1 signaling abnormalities in the Gata1low mouse model of myelofibrosis

Spleens of myelofibrosis patients contain malignant hematopoietic stem cells

(2012) Xiaoli Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1/2 study in patients with myelofibrosis

(2011) P. Guglielmelli et al.   BLOOD

TNF  facilitates clonal expansion of JAK2V617F positive cells in myeloproliferative neoplasms

(2011) A. G. Fleischman et al.   BLOOD

Targeting myeloproliferative neoplasms with JAK inhibitors

(2011) Animesh Pardanani et al.   CURRENT OPINION IN HEMATOLOGY

Odd-skipped maintains prohemocyte potency and blocks blood cell development in Drosophila

(2011) Hongjuan Gao et al.   GENESIS

Myeloproliferative Neoplasms: Molecular Pathophysiology, Essential Clinical Understanding, and Treatment Strategies

(2011) Ayalew Tefferi et al.   JOURNAL OF CLINICAL ONCOLOGY

Regulation of TGF-β signalling by protein phosphatases

(2010) Ting Liu et al.   BIOCHEMICAL JOURNAL

Evaluation of the bioactive and total transforming growth factor β1 levels in primary myelofibrosis

(2010) Rita Campanelli et al.   CYTOKINE

Protein Quality Control During Erythropoiesis and Hemoglobin Synthesis

(2010) Eugene Khandros et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

CXCR4-independent rescue of the myeloproliferative defect of the gata1low myelofibrosis mouse model by Aplidin®

(2010) Maria Verrucci et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Gata1 expression driven by the alternative HS2 enhancer in the spleen rescues the hematopoietic failure induced by the hypomorphic Gata1low mutation

(2009) A. R. Migliaccio et al.   BLOOD

Chemokines in hematopoiesis

(2009) Hal E Broxmeyer   CURRENT OPINION IN HEMATOLOGY

Pathological interactions between hematopoietic stem cells and their niche revealed by mouse models of primary myelofibrosis

(2009) Lilian Varricchio et al.   Expert Review of Hematology

Bone Morphogenetic Proteins Are Overexpressed in the Bone Marrow of Primary Myelofibrosis and Are Apparently Induced by Fibrogenic Cytokines

(2008) Oliver Bock et al.   AMERICAN JOURNAL OF PATHOLOGY

Igbp1 is part of a positive feedback loop in stem cell factor-dependent, selective mRNA translation initiation inhibiting erythroid differentiation

(2008) G. Grech et al.   BLOOD

Does primary myelofibrosis involve a defective stem cell niche? From concept to evidence

(2008) J.-J. Lataillade et al.   BLOOD

TGFβ in Cancer

(2008) Joan Massagué   CELL

Altered SDF-1/CXCR4 axis in patients with primary myelofibrosis and in the Gata1low mouse model of the disease

(2008) Anna Rita Migliaccio et al.   EXPERIMENTAL HEMATOLOGY

Allogeneic hematopoietic stem cell transplantation for myelofibrosis

(2008) D. Rondelli   HAEMATOLOGICA

Salmonella pathogenesis reveals that BMP signaling regulates blood cell homeostasis and immune responses in Drosophila

(2008) J. L. Frandsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypermethylation ofCXCR4Promoter in CD34+Cells from Patients with Primary Myelofibrosis

(2008) Costanza Bogani et al.   STEM CELLS