Pathological interactions between hematopoietic stem cells and their niche revealed by mouse models of primary myelofibrosis

Adaptor protein Lnk associates with Tyr568in c-Kit

(2008) Saskia Gueller et al.   BIOCHEMICAL JOURNAL

Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2

(2008) F. Grebien et al.   BLOOD

Transgenic expression of JAK2V617F causes myeloproliferative disorders in mice

(2008) S. Xing et al.   BLOOD

Lnk adaptor protein down-regulates specific Kit-induced signaling pathways in primary mast cells

(2008) C. Simon et al.   BLOOD

Selective Inhibition of JAK2-Driven Erythroid Differentiation of Polycythemia Vera Progenitors

(2008) Ifat Geron et al.   CANCER CELL

Recurrent der(9;18) in essential thrombocythemia with JAK2 V617F is highly linked to myelofibrosis development

(2008) Kazuma Ohyashiki et al.   CANCER GENETICS AND CYTOGENETICS

BCR/ABL and Other Kinases from Chronic Myeloproliferative Disorders Stimulate Single-Strand Annealing, an Unfaithful DNA Double-Strand Break Repair

(2008) K. Cramer et al.   CANCER RESEARCH

Negative regulation of Jak2 by its auto-phosphorylation at tyrosine 913 via the Epo signaling pathway

(2008) Megumi Funakoshi-Tago et al.   CELLULAR SIGNALLING

G-CSF stimulates Jak2-dependent Gab2 phosphorylation leading to Erk1/2 activation and cell proliferation

(2008) Lin Wang et al.   CELLULAR SIGNALLING

Normal Bone Anatomy and Physiology

(2008) B. Clarke   Clinical Journal of the American Society of Nephrology

Growth and maturation of megakaryocytes is regulated by Lnk/Sh2b3 adaptor protein through crosstalk between cytokine- and integrin-mediated signals

(2008) Hitoshi Takizawa et al.   EXPERIMENTAL HEMATOLOGY

Altered SDF-1/CXCR4 axis in patients with primary myelofibrosis and in the Gata1low mouse model of the disease

(2008) Anna Rita Migliaccio et al.   EXPERIMENTAL HEMATOLOGY

Familial chronic myeloproliferative disorders: the state of the art

(2008) Elisa Rumi   HEMATOLOGICAL ONCOLOGY

The proto-oncogene expression varies over the course of chronic myeloid leukemia

(2008) Ana Vidović et al.   Hematology

The myelodysplastic/myeloproliferative neoplasms: myeloproliferative diseases with dysplastic features

(2008) A Orazi et al.   LEUKEMIA

JAK2 and MPL mutations in myeloproliferative neoplasms: discovery and science

(2008) O Kilpivaara et al.   LEUKEMIA

JAKandMPLmutations in myeloid malignancies

(2008) Ayalew Tefferi   LEUKEMIA & LYMPHOMA

Primary myelofibrosis is the most frequent myeloproliferative neoplasm associated with del(5q): Clinicopathologic comparison of del(5q)-positive and -negative cases

(2008) Rafael Santana-Davila et al.   LEUKEMIA RESEARCH

Platelets, Petechiae, and Preservation of the Vascular Wall

(2008) Ralph L. Nachman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome

(2007) G. Kirsammer et al.   BLOOD