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Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway

(2011) Charlotte Hodson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype

(2011) Chantal Stoepker et al.   NATURE GENETICS

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia

(2011) Gerry P Crossan et al.   NATURE GENETICS

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(2011) Yonghwan Kim et al.   NATURE GENETICS

Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway

(2011) Ivan V Rosado et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Human FANCC is hypomorphic in murine Fancc-deficient cells

(2010) L. E. Hays et al.   BLOOD

Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage

(2010) A. Tulpule et al.   BLOOD

The various roles of ubiquitin in Wnt pathway regulation

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The EDD E3 ubiquitin ligase ubiquitinates and up-regulates β-catenin

(2010) Avital Hay-Koren et al.   MOLECULAR BIOLOGY OF THE CELL

Mutation of the RAD51C gene in a Fanconi anemia–like disorder

(2010) Fiona Vaz et al.   NATURE GENETICS

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

(2010) Alfons Meindl et al.   NATURE GENETICS

The structure of the catalytic subunit FANCL of the Fanconi anemia core complex

(2010) Ambrose R Cole et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Myc transcription factors: key regulators behind establishment and maintenance of pluripotency

(2010) Keriayn Smith et al.   Regenerative Medicine

How the Fanconi Anemia Pathway Guards the Genome

(2009) George-Lucian Moldovan et al.   Annual Review of Genetics

TLR8-dependent TNF-  overexpression in Fanconi anemia group C cells

(2009) S. M. Vanderwerf et al.   BLOOD

Wnt-Related Molecules and Signaling Pathway Equilibrium in Hematopoiesis

(2009) Sachin Malhotra et al.   Cell Stem Cell

Myelodysplasia and Acute Leukemia as Late Complications of Marrow Failure: Future Prospects for Leukemia Prevention

(2009) Grover C. Bagby et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells

(2009) Ángel Raya et al.   NATURE

Virus-Induced Chaperone-Enriched (VICE) Domains Function as Nuclear Protein Quality Control Centers during HSV-1 Infection

(2009) Christine M. Livingston et al.   PLoS Pathogens

HES1 is a novel interactor of the Fanconi anemia core complex

(2008) C. S. Tremblay et al.   BLOOD

Defective homing is associated with altered Cdc42 activity in cells from patients with Fanconi anemia group A

(2008) X. Zhang et al.   BLOOD

Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation

(2008) T. C. Luis et al.   BLOOD

Rad6B Is a Positive Regulator of  -Catenin Stabilization

(2008) M. P.V. Shekhar et al.   CANCER RESEARCH

Wnt Signaling in the Niche Enforces Hematopoietic Stem Cell Quiescence and Is Necessary to Preserve Self-Renewal In Vivo

(2008) Heather E. Fleming et al.   Cell Stem Cell

Atypical ubiquitin chains: new molecular signals. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Fumiyo Ikeda et al.   EMBO REPORTS

Mechanistic Insight into Site-Restricted Monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI

(2008) Arno F. Alpi et al.   MOLECULAR CELL

Jade-1 inhibits Wnt signalling by ubiquitylating β-catenin and mediates Wnt pathway inhibition by pVHL

(2008) Vipul C. Chitalia et al.   NATURE CELL BIOLOGY

Genome-Wide and Functional Annotation of Human E3 Ubiquitin Ligases Identifies MULAN, a Mitochondrial E3 that Regulates the Organelle's Dynamics and Signaling

(2008) Wei Li et al.   PLoS One