Emerging roles for multipotent, bone marrow-derived stromal cells in host defense

Mesenchymal Stem Cells: Mechanisms of Inflammation

(2011) Nora G. Singer et al.   Annual Review of Pathology-Mechanisms of Disease

Mesenchymal stem cells and autoimmune diseases

(2011) Francesco Dazzi et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

The impact of inflammatory licensing on heme oxygenase-1-mediated induction of regulatory T cells by human mesenchymal stem cells

(2011) D. Mougiakakos et al.   BLOOD

Thymic T-cell development in allogeneic stem cell transplantation

(2011) W. Krenger et al.   BLOOD

Bone Marrow Mesenchymal Stem and Progenitor Cells Induce Monocyte Emigration in Response to Circulating Toll-like Receptor Ligands

(2011) Chao Shi et al.   IMMUNITY

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

CM-DiI Labeled Mesenchymal stem cells homed to thymus inducing immune recovery of mice after haploidentical bone marrow transplantation

(2011) Kai-xun Hu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in

(2011) Armin Ehninger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mesenchymal stromal cell ‘licensing’: a multistep process

(2011) M Krampera   LEUKEMIA

Human but not murine multipotent mesenchymal stromal cells exhibit broad-spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase

(2011) R Meisel et al.   LEUKEMIA

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

Toll-Like Receptor-3-Activated Human Mesenchymal Stromal Cells Significantly Prolong the Survival and Function of Neutrophils

(2011) Marco A. Cassatella et al.   STEM CELLS

Mesenchymal Stem Cells Reduce Inflammation while Enhancing Bacterial Clearance and Improving Survival in Sepsis

(2010) Shirley H. J. Mei et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Chemotherapy-induced mesenchymal stem cell damage in patients with hematological malignancy

(2010) Kevin Kemp et al.   ANNALS OF HEMATOLOGY

HMGB1 and RAGE in Inflammation and Cancer

(2010) Gary P. Sims et al.   Annual Review of Immunology

MSCs in Hematopoietic Cell Transplantation

(2010) Edwin M. Horwitz et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Bone marrow graft-versus-host disease: early destruction of hematopoietic niche after MHC-mismatched hematopoietic stem cell transplantation

(2010) Y. Shono et al.   BLOOD

Mesenchymal Stromal Cells: Facilitators of Successful Transplantation?

(2010) Karen English et al.   Cell Stem Cell

Inflammation modifies the pattern and the function of Toll-like receptors expressed by human mesenchymal stromal cells

(2010) Gordana Raicevic et al.   HUMAN IMMUNOLOGY

Inflammatory Cytokine-Induced Intercellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule-1 in Mesenchymal Stem Cells Are Critical for Immunosuppression

(2010) Guangwen Ren et al.   JOURNAL OF IMMUNOLOGY

Modulation of Adult Mesenchymal Stem Cells Activity by Toll-Like Receptors: Implications on Therapeutic Potential

(2010) Olga DelaRosa et al.   MEDIATORS OF INFLAMMATION

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

A New Mesenchymal Stem Cell (MSC) Paradigm: Polarization into a Pro-Inflammatory MSC1 or an Immunosuppressive MSC2 Phenotype

(2010) Ruth S. Waterman et al.   PLoS One

New Insights into Mesenchymal Stromal Cell-Mediated T-Cell Suppression Through Galectins

(2010) M. Sioud   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Antibacterial Effect of Human Mesenchymal Stem Cells Is Mediated in Part from Secretion of the Antimicrobial Peptide LL-37

(2010) Anna Krasnodembskaya et al.   STEM CELLS

New concepts on the immune modulation mediated by mesenchymal stem cells

(2010) Bruce A Bunnell et al.   Stem Cell Research & Therapy

Regulatory T Cells in the Control of Host-Microorganism Interactions

(2009) Yasmine Belkaid et al.   Annual Review of Immunology

Adult Human Mesenchymal Stem Cells Added to Corticosteroid Therapy for the Treatment of Acute Graft-versus-Host Disease

(2009) Partow Kebriaei et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Regenerative Stromal Cell Therapy in Allogeneic Hematopoietic Stem Cell Transplantation: Current Impact and Future Directions

(2009) Jeffery J. Auletta et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Cell contact, prostaglandin E2and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25Highforkhead box P3+regulatory T cells

(2009) K. English et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Mesenchymal stem cell–educated macrophages: A novel type of alternatively activated macrophages

(2009) Jaehyup Kim et al.   EXPERIMENTAL HEMATOLOGY

Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis

(2009) E Gonzalez-Rey et al.   GUT

Cytokine Modulation of TLR Expression and Activation in Mesenchymal Stromal Cells Leads to a Proinflammatory Phenotype

(2009) R. Romieu-Mourez et al.   JOURNAL OF IMMUNOLOGY

Modulation of bone marrow stromal cell functions in infectious diseases by toll-like receptor ligands

(2009) Krisztian Nemeth et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Toll-Like Receptor Engagement Enhances the Immunosuppressive Properties of Human Bone Marrow-Derived Mesenchymal Stem Cells by Inducing Indoleamine-2,3-dioxygenase-1 via Interferon-β and Protein Kinase R

(2009) Christiane A. Opitz et al.   STEM CELLS

Human mesenchymal stem cells stimulated by TNF-α, LPS, or hypoxia produce growth factors by an NFκB- but not JNK-dependent mechanism

(2008) Paul R. Crisostomo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Persistence of Human Parvovirus B19 in Multipotent Mesenchymal Stromal Cells Expressing the Erythrocyte P Antigen: Implications for Transplantation

(2008) Mikael Sundin et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Mesenchymal stem cells exert differential effects on alloantigen and virus-specific T-cell responses

(2008) H. Karlsson et al.   BLOOD

The role of indoleamine 2,3-dioxygenase in the induction of immune tolerance: focus on hematology

(2008) A. Curti et al.   BLOOD

CD4 T cells: fates, functions, and faults

(2008) J. Zhu et al.   BLOOD

Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

(2008) Guangwen Ren et al.   Cell Stem Cell

IFN-γ activation of mesenchymal stem cells for treatment and prevention of graft versus host disease

(2008) David Polchert et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inflammatory Response in Microvascular Endothelium in Sepsis: Role of Oxidants

(2008) Gediminas Cepinskas et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

(2008) Katarina Le Blanc et al.   LANCET

Indoleamine 2,3-dioxygenase in infection: the paradox of an evasive strategy that benefits the host

(2008) T ZELANTE et al.   MICROBES AND INFECTION

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

(2008) Krisztián Németh et al.   NATURE MEDICINE

Paracrine Factors of Mesenchymal Stem Cells Recruit Macrophages and Endothelial Lineage Cells and Enhance Wound Healing

(2008) Liwen Chen et al.   PLoS One

Toll-like Receptor–Mediated Signaling in Human Adipose-Derived Stem Cells: Implications for Immunogenicity and Immunosuppressive Potential

(2008) Eleuterio Lombardo et al.   TISSUE ENGINEERING PART A

Toll-Like Receptors 3 and 4 Are Expressed by Human Bone Marrow-Derived Mesenchymal Stem Cells and Can Inhibit Their T-Cell Modulatory Activity by Impairing Notch Signaling

(2007) Francesco Liotta et al.   STEM CELLS

Toll-Like Receptors on Human Mesenchymal Stem Cells Drive Their Migration and Immunomodulating Responses

(2007) Suzanne L. Tomchuck et al.   STEM CELLS