Process for immune defect and chromosomal translocation during early thymocyte development lacking ATM

Mechanisms that Promote and Suppress Chromosomal Translocations in Lymphocytes

(2011) Monica Gostissa et al.   Annual Review of Immunology

ATM protein kinase: the linchpin of cellular defenses to stress

(2011) Shahzad Bhatti et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Functional characterization and targeted correction of ATM mutations identified in Japanese patients with ataxia-telangiectasia

(2011) Kotoka Nakamura et al.   HUMAN MUTATION

RAG-induced DNA double-strand breaks signal through Pim2 to promote pre–B cell survival and limit proliferation

(2011) Jeffrey J. Bednarski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Aurora-B Mediated ATM Serine 1403 Phosphorylation Is Required for Mitotic ATM Activation and the Spindle Checkpoint

(2011) Chunying Yang et al.   MOLECULAR CELL

The RAG2 C terminus suppresses genomic instability and lymphomagenesis

(2011) Ludovic Deriano et al.   NATURE

ATM-deficient thymic lymphoma is associated with aberranttcrdrearrangement and gene amplification

(2010) Shan Zha et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

(2010) M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Essential Developmental Checkpoint for Production of the T Cell Lineage

(2010) T. Ikawa et al.   SCIENCE

Phenotypic variations between affected siblings with ataxia-telangiectasia: ataxia-telangiectasia in Japan

(2009) Tomohiro Morio et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Thymic development beyond β-selection requires phosphatidylinositol 3-kinase activation by CXCR4

(2009) Michelle L. Janas et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CXCR4 acts as a costimulator during thymic β-selection

(2009) Paul C Trampont et al.   NATURE IMMUNOLOGY

ATM and p53 are essential in the cell-cycle containment of DNA breaks during V(D)J recombination in vivo

(2009) M E Dujka et al.   ONCOGENE

Regulation of Tcrb recombination ordering by c-Fos-dependent RAG deposition

(2008) Xiaoming Wang et al.   NATURE IMMUNOLOGY

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

(2008) Martin F. Lavin   NATURE REVIEWS MOLECULAR CELL BIOLOGY