Serotonin 5-HT2B receptors are required for bone-marrow contribution to pulmonary arterial hypertension

C-Kit–Positive Cells Accumulate in Remodeled Vessels of Idiopathic Pulmonary Arterial Hypertension

(2011) David Montani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Bad blood, bad endothelium: ill fate?

(2011) M. Yoder et al.   BLOOD

Hypoxia-inducible factors in human pulmonary arterial hypertension: a link to the intrinsic myeloid abnormalities

(2011) S. Farha et al.   BLOOD

C-122, a novel antagonist of serotonin receptor 5-HT2B, prevents monocrotaline-induced pulmonary arterial hypertension in rats

(2011) David A. Zopf et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ineffective erythropoiesis with reduced red blood cell survival in serotonin-deficient mice

(2011) Pascal Amireault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imatinib in Pulmonary Arterial Hypertension Patients with Inadequate Response to Established Therapy

(2010) Hossein A. Ghofrani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Basic Science of Pulmonary Arterial Hypertension for Clinicians

(2010) Stephen L. Archer et al.   CIRCULATION

Terguride ameliorates monocrotaline-induced pulmonary hypertension in rats

(2010) R. Dumitrascu et al.   EUROPEAN RESPIRATORY JOURNAL

Targeting of c-kit+ haematopoietic progenitor cells prevents hypoxic pulmonary hypertension

(2010) N. Gambaryan et al.   EUROPEAN RESPIRATORY JOURNAL

Imatinib inhibits bone marrow-derived c-kit+ cell mobilisation in hypoxic pulmonary hypertension

(2010) N. Gambaryan et al.   EUROPEAN RESPIRATORY JOURNAL

PRX-08066, a Novel 5-Hydroxytryptamine Receptor 2B Antagonist, Reduces Monocrotaline-Induced Pulmonary Arterial Hypertension and Right Ventricular Hypertrophy in Rats

(2010) S. L. Porvasnik et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Endothelial Progenitor Cells in Pulmonary Arterial Hypertension

(2010) Gerhard-Paul Diller et al.   TRENDS IN CARDIOVASCULAR MEDICINE

The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease

(2009) T. R. Hercus et al.   BLOOD

Parallel Functional Activity Profiling Reveals Valvulopathogens Are Potent 5-Hydroxytryptamine2B Receptor Agonists: Implications for Drug Safety Assessment

(2009) X.-P. Huang et al.   MOLECULAR PHARMACOLOGY

Circulating Angiogenic Precursors in Idiopathic Pulmonary Arterial Hypertension

(2008) Kewal Asosingh et al.   AMERICAN JOURNAL OF PATHOLOGY

Fenfluramine: riddle or Rosetta stone?

(2008) E. K. Weir et al.   EUROPEAN RESPIRATORY JOURNAL

Sustained Endothelial Progenitor Cell Dysfunction After Chronic Hypoxia-Induced Pulmonary Hypertension

(2008) Glenn Marsboom et al.   STEM CELLS

Bone marrow progenitor cells contribute to repair and remodeling of the lung and heart in a rat model of progressive pulmonary hypertension

(2007) Jeffrey L. Spees et al.   FASEB JOURNAL

Activation of c-kit is necessary for mobilization of reparative bone marrow progenitor cells in response to cardiac injury

(2007) Shafie S. Fazel et al.   FASEB JOURNAL

Pathogenic mechanisms of pulmonary arterial hypertension

(2007) Stephen Y. Chan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY