Constitutive Notch pathway activation in murine ZMYM2-FGFR1-induced T-cell lymphomas associated with atypical myeloproliferative disease

Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice

(2010) H. Agerstam et al.   BLOOD

Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL

(2010) R. Jeannet et al.   BLOOD

Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1

(2010) T. D. Ashworth et al.   BLOOD

8p11 myeloproliferative syndrome: a review

(2010) Courtney C. Jackson et al.   HUMAN PATHOLOGY

Alternative Promoter Usage at the Notch1 Locus Supports Ligand-Independent Signaling in T Cell Development and Leukemogenesis

(2010) Pablo Gómez-del Arco et al.   IMMUNITY

Notch Signaling in the Immune System

(2010) Freddy Radtke et al.   IMMUNITY

Therapeutic antibody targeting of individual Notch receptors

(2010) Yan Wu et al.   NATURE

Targeted next-generation sequencing of DNA regions proximal to a conserved GXGXXG signaling motif enables systematic discovery of tyrosine kinase fusions in cancer

(2010) Juliann Chmielecki et al.   NUCLEIC ACIDS RESEARCH

t(8;13)-positive Bilineal Lymphomas

(2009) Francisco Vega et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Genetic fingerprinting of the development and progression of T-cell lymphoma in a murine model of atypical myeloproliferative disorder initiated by the ZNF198-fibroblast growth factor receptor-1 chimeric tyrosine kinase

(2009) M. Ren et al.   BLOOD

Molecular Monitoring of 8p11 Myeloproliferative Syndrome in an Infant

(2009) Wenyong W. Zhang et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Direct inhibition of the NOTCH transcription factor complex

(2009) Raymond E. Moellering et al.   NATURE

Notch Signaling in Leukemia

(2008) Jon C. Aster et al.   Annual Review of Pathology-Mechanisms of Disease

Notch Signaling Specifies Megakaryocyte Development from Hematopoietic Stem Cells

(2008) Thomas Mercher et al.   Cell Stem Cell

Therapeutic Potential of γ -Secretase Inhibitors and Modulators

(2008) Bruno Imbimbo   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras–initiated leukemia

(2008) Mark Y. Chiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1

(2008) Xiaoyu Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

(2008) Pedro J Real et al.   NATURE MEDICINE

Genomic analysis of CD8+ NK/T cell line, ‘SRIK-NKL’, with array-based CGH (aCGH), SKY/FISH and molecular mapping

(2007) Michael R. Rossi et al.   LEUKEMIA RESEARCH

The 8p11 myeloproliferative syndrome in a 3-year-old child

(2007) Baris Kuskonmaz et al.   LEUKEMIA RESEARCH