Primary cilia in pancreatic development and disease

Pancreas Organogenesis: From Lineage Determination to Morphogenesis

(2013) Hung Ping Shih et al.   Annual Review of Cell and Developmental Biology

Mutations in NEK8 link multiple organ dysplasia with altered Hippo signalling and increased c-MYC expression

(2013) Valeska Frank et al.   HUMAN MOLECULAR GENETICS

The islet ghrelin cell

(2013) Nils Wierup et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Sfrp5 Modulates Both Wnt and BMP Signaling and Regulates Gastrointestinal Organogensis in the Zebrafish, Danio rerio

(2013) Carsten Stuckenholz et al.   PLoS One

TGF-β Signaling Is Associated with Endocytosis at the Pocket Region of the Primary Cilium

(2013) Christian Alexandro Clement et al.   Cell Reports

The Prevalence of Diabetes Among Overweight and Obese Individuals is Higher in Poorer than in Richer Neighbourhoods

(2012) Murray M. Finkelstein   Canadian Journal of Diabetes

BBS-Induced Ciliary Defect Enhances Adipogenesis, Causing Paradoxical Higher-Insulin Sensitivity, Glucose Usage, and Decreased Inflammatory Response

(2012) Vincent Marion et al.   Cell Metabolism

Alstrom Syndrome: Genetics and Clinical Overview

(2012) Jan D. Marshall et al.   CURRENT GENOMICS

A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation

(2012) H. P. Shih et al.   DEVELOPMENT

The ontogeny of the endocrine pancreas in the fetal/newborn baboon

(2012) Amy R Quinn et al.   JOURNAL OF ENDOCRINOLOGY

Ift88 regulates Hedgehog signaling,Sfrp5expression, and β-catenin activity in post-natal growth plate

(2012) Ching-Fang Chang et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Exploring the Transcriptome of Ciliated Cells Using In Silico Dissection of Human Tissues

(2012) Alexander E. Ivliev et al.   PLoS One

Exocrine ontogenies: On the development of pancreatic acinar, ductal and centroacinar cells

(2012) Megan H. Cleveland et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Regulation of TGF-β receptor activity

(2012) Fei Huang et al.   Cell and Bioscience

The ciliary pocket: a once-forgotten membrane domain at the base of cilia

(2011) Rania Ghossoub et al.   BIOLOGY OF THE CELL

A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development

(2011) Ellen J. Ezratty et al.   CELL

Pancreas organogenesis: From bud to plexus to gland

(2011) Fong Cheng Pan et al.   DEVELOPMENTAL DYNAMICS

Patients with Bardet-Biedl Syndrome Have Hyperleptinemia Suggestive of Leptin Resistance

(2011) Penelope P. Feuillan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Pancreatic ductal cells in development, regeneration, and neoplasia

(2011) Maximilian Reichert et al.   JOURNAL OF CLINICAL INVESTIGATION

The progression from obesity to type 2 diabetes in Alström syndrome

(2011) Vera Bettini et al.   PEDIATRIC DIABETES

Elevated Hedgehog/Gli signaling causes  -cell dedifferentiation in mice

(2011) L. Landsman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hyperactive Neuroendocrine Secretion Causes Size, Feeding, and Metabolic Defects of C. elegans Bardet-Biedl Syndrome Mutants

(2011) Brian H. Lee et al.   PLOS BIOLOGY

Fibrocystic disease of liver and pancreas; under-recognized features of the X-linked ciliopathy oral-facial-digital syndrome type 1 (OFD I)

(2010) Shilpa Chetty-John et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Notch signalling regulates left-right asymmetry through ciliary length control

(2010) S. S. Lopes et al.   DEVELOPMENT

The Transcription Factor Rfx3 Regulates  -Cell Differentiation, Function, and Glucokinase Expression

(2010) A. Ait-Lounis et al.   DIABETES

The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia

(2010) A. Molla-Herman et al.   JOURNAL OF CELL SCIENCE

Alström syndrome: insights into the pathogenesis of metabolic disorders

(2010) Dorothée Girard et al.   Nature Reviews Endocrinology

Primary cilia regulate Gli/Hedgehog activation in pancreas

(2010) S. Cervantes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pancreatic islet plasticity: Interspecies comparison of islet architecture and composition

(2010) Donald J. Steiner et al.   Islets

The what, where, when and how of Wnt/β-catenin signaling in pancreas development

(2010) L. Charles Murtaugh   Organogenesis

Caloric restriction in Alström syndrome prevents hyperinsulinemia

(2009) Ni-Chung Lee et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Vertebrate Endoderm Development and Organ Formation

(2009) Aaron M. Zorn et al.   Annual Review of Cell and Developmental Biology

Pancreatic Cancer and Precursor Pancreatic Intraepithelial Neoplasia Lesions Are Devoid of Primary Cilia

(2009) E. S. Seeley et al.   CANCER RESEARCH

The Vertebrate Primary Cilium in Development, Homeostasis, and Disease

(2009) Jantje M. Gerdes et al.   CELL

The Mammalian Cos2 Homolog Kif7 Plays an Essential Role in Modulating Hh Signal Transduction during Development

(2009) Setsu Endoh-Yamagami et al.   CURRENT BIOLOGY

Notch signaling controls liver development by regulating biliary differentiation

(2009) Y. Zong et al.   DEVELOPMENT

Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas

(2009) Sui Wang et al.   DEVELOPMENTAL BIOLOGY

Presenilins, Notch dose control the fate of pancreatic endocrine progenitors during a narrow developmental window

(2009) C. Cras-Meneur et al.   GENES & DEVELOPMENT

Endocrine Cell Clustering During Human Pancreas Development

(2009) Jongmin Jeon et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Conditional Mutation of Pkd2 Causes Cystogenesis and Upregulates  -Catenin

(2009) I. Kim et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation

(2009) Hongjie Zhang et al.   MECHANISMS OF DEVELOPMENT

Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas

(2009) Michael J. Parsons et al.   MECHANISMS OF DEVELOPMENT

Zebrafish pancreas development

(2009) Natascia Tiso et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

FGF signalling during embryo development regulates cilia length in diverse epithelia

(2009) Judith M. Neugebauer et al.   NATURE

Sonic hedgehog paracrine signaling regulates metastasis and lymphangiogenesis in pancreatic cancer

(2009) J M Bailey et al.   ONCOGENE

Deciphering von Hippel-Lindau (VHL/Vhl)-Associated Pancreatic Manifestations by Inactivating Vhl in Specific Pancreatic Cell Populations

(2009) H.-C. Jennifer Shen et al.   PLoS One

FGF-dependent left-right asymmetry patterning in zebrafish is mediated by Ier2 and Fibp1

(2009) S.-K. Hong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus

(2009) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of Nephrocystin-3 Function Can Cause Embryonic Lethality, Meckel-Gruber-like Syndrome, Situs Inversus, and Renal-Hepatic-Pancreatic Dysplasia

(2008) Carsten Bergmann et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Biliary and Pancreatic Dysgenesis in Mice Harboring a Mutation in Pkhd1

(2008) Anna-Rachel Gallagher et al.   AMERICAN JOURNAL OF PATHOLOGY

Hedgehog signalling

(2008) Philip W. Ingham   CURRENT BIOLOGY

Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells

(2008) Jared S. Burlison et al.   DEVELOPMENTAL BIOLOGY

Developmental biology of the pancreas: A comprehensive review

(2008) George K. Gittes   DEVELOPMENTAL BIOLOGY

Characterization of primary cilia and Hedgehog signaling during development of the human pancreas and in human pancreatic duct cancer cell lines

(2008) Sonja K. Nielsen et al.   DEVELOPMENTAL DYNAMICS

Ghrelin-producing epsilon cells in the developing and adult human pancreas

(2008) K. M. Andralojc et al.   DIABETOLOGIA

Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling

(2008) Y. Li et al.   GENES & DEVELOPMENT

Genes controlling pancreas ontogeny

(2008) Claire Bonal et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY