Genetic studies ofANKRD6as a molecular switch between Wnt signaling pathways in human neural tube defects

 -catenin regulates Pax3 and Cdx2 for caudal neural tube closure and elongation

(2013) T. Zhao et al.   DEVELOPMENT

Novel mutations in Lrp6 orthologs in mouse and human neural tube defects affect a highly dosage-sensitive Wnt non-canonical planar cell polarity pathway

(2013) Redouane Allache et al.   HUMAN MOLECULAR GENETICS

A consideration of the evidence that genetic defects in planar cell polarity contribute to the etiology of human neural tube defects

(2012) Diana M. Juriloff et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

The complex world of WNT receptor signalling

(2012) Christof Niehrs   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The emerging role of epigenetic mechanisms in the etiology of neural tube defects

(2011) Nicholas D.E. Greene et al.   Epigenetics

FZD6is a novel gene for human neural tube defects

(2011) Patrizia De Marco et al.   HUMAN MUTATION

Identification and characterization of novel rare mutations in the planar cell polarity genePRICKLE1in human neural tube defects

(2011) Ciprian M. Bosoi et al.   HUMAN MUTATION

A Wnt Survival Guide: From Flies to Human Disease

(2009) Andy J. Chien et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway

(2009) Isabelle Roszko et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Genetic Basis of Neural Tube Defects

(2009) Alexander G. Bassuk et al.   Seminars in Pediatric Neurology

Planar Cell Polarity Signaling: From Fly Development to Human Disease

(2008) Matias Simons et al.   Annual Review of Genetics

The Extracellular Domain of Lrp5/6 Inhibits Noncanonical Wnt Signaling In Vivo

(2008) Vitezslav Bryja et al.   MOLECULAR BIOLOGY OF THE CELL