Commonality in Down and fetal alcohol syndromes

A Pilot Study Examining Associations between DYRK1A and a-Synuclein Dementias

(2012) Emma L. Jones et al.   Neurodegenerative Diseases

Strain Differences in Developmental Vulnerability to Alcohol Exposure via Embryo Culture in Mice

(2011) Yuanyuan Chen et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

A practical guide to evaluating colocalization in biological microscopy

(2011) Kenneth W. Dunn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Calcium-mediated repression of β-catenin and its transcriptional signaling mediates neural crest cell death in an avian model of fetal alcohol syndrome

(2011) George R. Flentke et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Two key genes closely implicated with the neuropathological characteristics in Down syndrome: DYRK1A and RCAN1

(2011) Joong-Kyu Park et al.   BMB Reports

Novel mutations of TCOF1 gene in European patients with treacher Collins syndrome

(2011) Chiara Conte et al.   BMC Medical Genetics

Infections and immunodeficiency in Down syndrome

(2011) G. Ram et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Down syndrome: searching for the genetic culprits

(2011) E. Lana-Elola et al.   Disease Models & Mechanisms

Trisomic and Allelic Differences Influence Phenotypic Variability During Development of Down Syndrome Mice

(2011) Samantha L. Deitz et al.   GENETICS

The Regulator of Calcineurin 1 (RCAN1/DSCR1) Activates the cAMP Response Element-binding Protein (CREB) Pathway

(2011) Seon Sook Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulator of Calcineurin 1 (RCAN1) Facilitates Neuronal Apoptosis through Caspase-3 Activation

(2011) Xiulian Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn

(2011) Laura G. Reinholdt et al.   MAMMALIAN GENOME

Fetal Alcohol Spectrum Disorders: An Overview

(2011) Edward P. Riley et al.   NEUROPSYCHOLOGY REVIEW

S100B and APP Promote a Gliocentric Shift and Impaired Neurogenesis in Down Syndrome Neural Progenitors

(2011) Jie Lu et al.   PLoS One

Alcohol-induced facial dysmorphology in C57BL/6 mouse models of fetal alcohol spectrum disorder

(2010) Bruce Anthony et al.   ALCOHOL

Verbal and Nonverbal Memory in Adults Prenatally Exposed to Alcohol

(2010) Claire D. Coles et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective effect of rapamycin in neonatal hypoxia-ischemia

(2010) Silvia Carloni et al.   Autophagy

Magnetic resonance microscopy-based analyses of the brains of normal and ethanol-exposed fetal mice

(2010) Shonagh K. O'Leary-Moore et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Embryonic and not maternal trisomy causes developmental attenuation in the Ts65Dn mouse model for Down syndrome

(2010) Joshua D. Blazek et al.   DEVELOPMENTAL DYNAMICS

Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation

(2010) Yunlong Liu et al.   Epigenetics

Prevalence of congenital heart defects and persistent pulmonary hypertension of the neonate with Down syndrome

(2010) Michel Emile Weijerman et al.   EUROPEAN JOURNAL OF PEDIATRICS

The role of DYRK1A in neurodegenerative diseases

(2010) Jerzy Wegiel et al.   FEBS Journal

Dyrk1A Overexpression Inhibits Proliferation and Induces Premature Neuronal Differentiation of Neural Progenitor Cells

(2010) O. Yabut et al.   JOURNAL OF NEUROSCIENCE

Early Pharmacotherapy Restores Neurogenesis and Cognitive Performance in the Ts65Dn Mouse Model for Down Syndrome

(2010) P. Bianchi et al.   JOURNAL OF NEUROSCIENCE

Reversal of Alcohol-Induced Learning Deficits in the Young Adult in a Model of Fetal Alcohol Syndrome

(2010) Maddalena Incerti et al.   OBSTETRICS AND GYNECOLOGY

Bone mass in male and female children and adolescents with Down syndrome

(2010) A. González-Agüero et al.   OSTEOPOROSIS INTERNATIONAL

Prenatal alcohol exposure triggers ceramide-induced apoptosis in neural crest-derived tissues concurrent with defective cranial development

(2010) G Wang et al.   Cell Death & Disease

Review of published studies of kidney, liver, and gastrointestinal birth defects in fetal alcohol spectrum disorders

(2009) Ryan Hofer et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Widespread impairment of cell proliferation in the neonate Ts65Dn mouse, a model for Down syndrome

(2009) A. Contestabile et al.   CELL PROLIFERATION

The E3 Ligase TTC3 Facilitates Ubiquitination and Degradation of Phosphorylated Akt

(2009) Futoshi Suizu et al.   DEVELOPMENTAL CELL

Prevalence and epidemiologic characteristics of FASD from various research methods with an emphasis on recent in-school studies

(2009) Philip A. May et al.   Developmental Disabilities Research Reviews

Neuroimaging and fetal alcohol spectrum disorders

(2009) Andria L. Norman et al.   Developmental Disabilities Research Reviews

Molecular genetic analysis of Down syndrome

(2009) David Patterson   HUMAN GENETICS

Down syndrome--recent progress and future prospects

(2009) F. K. Wiseman et al.   HUMAN MOLECULAR GENETICS

Otitis media in a mouse model for Down syndrome

(2009) Fengchan Han et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

UK and Ireland experience of cochlear implants in children with Down Syndrome

(2009) P.S. Hans et al.   INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY

Negative Feedback Inhibition of NFATc1 by DYRK1A Regulates Bone Homeostasis

(2009) Youngkyun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of maternal alcohol consumption during breastfeeding on motor and cerebellar Purkinje cells behavior in mice

(2009) Ana Maria Cebolla et al.   NEUROSCIENCE LETTERS

Increased Prevalence of Renal and Urinary Tract Anomalies in Children With Down Syndrome

(2009) J. C. Kupferman et al.   PEDIATRICS

Phenotype of apoptotic lymphocytes in children with Down syndrome

(2009) Solaf M Elsayed et al.   Immunity & Ageing

Truncation of the Down Syndrome Candidate Gene DYRK1A in Two Unrelated Patients with Microcephaly

(2008) Rikke S. Møller et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Alterations in phosphorylated cyclic adenosine monophosphate response element of binding protein activity: a pathway for fetal alcohol syndrome-related neurotoxicity

(2008) Robin Roberson et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Fetal ethanol exposure activates protein kinase a and impairsShh expression in prechordal mesendoderm cells in the pathogenesis of holoprosencephaly

(2008) Kazushi Aoto et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

The facial phenotype of the velo-cardio-facial syndrome

(2008) Sydney C. Butts   INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY

Convergence of integrins and EGF receptor signaling via PI3K/Akt/FoxO pathway in early gene Egr-1 expression

(2008) Sara Cabodi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A neural crest deficit in Down syndrome mice is associated with deficient mitotic response to Sonic hedgehog

(2008) Randall J. Roper et al.   MECHANISMS OF DEVELOPMENT

Fetal alcohol syndrome: a prospective national surveillance study

(2007) E J Elliott et al.   ARCHIVES OF DISEASE IN CHILDHOOD