Two key genes closely implicated with the neuropathological characteristics in Down syndrome: DYRK1A and RCAN1

The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome

(2008) Jerzy Wegiel et al.   ACTA NEUROPATHOLOGICA

Targeted Deletion of the Calcineurin Inhibitor DSCR1 Suppresses Tumor Growth

(2008) Sandra Ryeom et al.   CANCER CELL

c-Jun Inhibits Thapsigargin-Induced ER Stress Through Up-Regulation of DSCR1/Adapt78

(2008) Peng Zhao et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome

(2008) Fei Liu et al.   FASEB JOURNAL

DSCR1/RCAN1 regulates vesicle exocytosis and fusion pore kinetics: implications for Down syndrome and Alzheimer's disease

(2008) Damien J. Keating et al.   HUMAN MOLECULAR GENETICS

Transcription Enhancer Factor 3 (TEF3) Mediates the Expression of Down Syndrome Candidate Region 1 Isoform 1 (DSCR1-1L) in Endothelial Cells

(2008) Xin Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased NR2A expression and prolonged decay of NMDA-induced calcium transient in cerebellum of TgDyrk1A mice, a mouse model of Down syndrome

(2008) X. Altafaj et al.   NEUROBIOLOGY OF DISEASE

The down syndrome candidate dual-specificity tyrosine phosphorylation-regulated kinase 1A phosphorylates the neurodegeneration-related septin 4

(2008) J.H. Sitz et al.   NEUROSCIENCE

Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer’s disease

(2007) Soo-Ryoon Ryoo et al.   JOURNAL OF NEUROCHEMISTRY