A CHO cell line engineered to express XBP1 and ERO1-Lα has increased levels of transient protein expression

Identifying bottlenecks in transient and stable production of recombinant monoclonal-antibody sequence variants in chinese hamster ovary cells

(2012) Megan Mason et al.   BIOTECHNOLOGY PROGRESS

Manufacturing recombinant proteins in kg-ton quantities using animal cells in bioreactors

(2011) Maria De Jesus et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

A simple high-yielding process for transient gene expression in CHO cells

(2011) Yashas Rajendra et al.   JOURNAL OF BIOTECHNOLOGY

Effect of inducible co-overexpression of protein disulfide isomerase and endoplasmic reticulum oxidoreductase on the specific antibody productivity of recombinant Chinese hamster ovary cells

(2010) Chaya Mohan et al.   BIOTECHNOLOGY AND BIOENGINEERING

Valproic acid enhances recombinant mRNA and protein levels in transiently transfected Chinese hamster ovary cells

(2010) Sarah Wulhfard et al.   JOURNAL OF BIOTECHNOLOGY

Mcl-1 overexpression leads to higher viabilities and increased production of humanized monoclonal antibody in Chinese hamster ovary cells

(2009) Brian S. Majors et al.   BIOTECHNOLOGY PROGRESS

Evaluation of a combinatorial cell engineering approach to overcome apoptotic effects in XBP-1(s) expressing cells

(2009) Eric Becker et al.   JOURNAL OF BIOTECHNOLOGY

Enhancement of transient gene expression and culture viability using Chinese hamster ovary cells overexpressing Bcl-xL

(2008) Brian S. Majors et al.   BIOTECHNOLOGY AND BIOENGINEERING

Mild Hypothermia Improves Transient Gene Expression Yields Several Fold in Chinese Hamster Ovary Cells

(2008) S. Wulhfard et al.   BIOTECHNOLOGY PROGRESS

An XBP-1 dependent bottle-neck in production of IgG subtype antibodies in chemically defined serum-free Chinese hamster ovary (CHO) fed-batch processes

(2008) E BECKER et al.   JOURNAL OF BIOTECHNOLOGY

Coexpression of acidic fibroblast growth factor enhances specific productivity and antibody titers in transiently transfected HEK293 cells

(2008) Gaurav Backliwal et al.   New Biotechnology

Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

(2008) J. D. Malhotra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of Increased Expression of Protein Disulfide Isomerase and Heavy Chain Binding Protein on Antibody Secretion in a Recombinant CHO Cell Line

(2005) Nicole Borth et al.   BIOTECHNOLOGY PROGRESS