Identifying bottlenecks in transient and stable production of recombinant monoclonal-antibody sequence variants in chinese hamster ovary cells

Cell line-specific control of recombinant monoclonal antibody production by CHO cells

(2010) Peter M. O'Callaghan et al.   BIOTECHNOLOGY AND BIOENGINEERING

The influence of the framework core residues on the biophysical properties of immunoglobulin heavy chain variable domains

(2009) Annemarie Honegger et al.   PROTEIN ENGINEERING DESIGN & SELECTION

How antibodies fold

(2009) Matthias J. Feige et al.   TRENDS IN BIOCHEMICAL SCIENCES

The absence of effect of gene copy number and mRNA level on the amount of mAb secretion from mammalian cells

(2008) Hannes Reisinger et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Identification of the limitations on recombinant gene expression in CHO cell lines with varying luciferase production rates

(2008) Emma J. Mead et al.   BIOTECHNOLOGY AND BIOENGINEERING

A study of monoclonal antibody-producing CHO cell lines: What makes a stable high producer?

(2008) Janet Chusainow et al.   BIOTECHNOLOGY AND BIOENGINEERING

A clone screening method using mRNA levels to determine specific productivity and product quality for monoclonal antibodies

(2008) Christina J. Lee et al.   BIOTECHNOLOGY AND BIOENGINEERING

High throughput methods of assessing protein stability and aggregation

(2008) Guillermo A. Senisterra et al.   Molecular BioSystems

Conserved amino acid networks involved in antibody variable domain interactions

(2008) Norman Wang et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS