Unstable expression of recombinant antibody during long-term culture of CHO cells is accompanied by histone H3 hypoacetylation

Determination of Chinese hamster ovary cell line stability and recombinant antibody expression during long-term culture

(2012) Laura A Bailey et al.   BIOTECHNOLOGY AND BIOENGINEERING

Position effect variegation and epigenetic modification of a transgene in a pig model

(2012) Z. Yin et al.   GENETICS AND MOLECULAR RESEARCH

A mechanistic understanding of production instability in CHO cell lines expressing recombinant monoclonal antibodies

(2011) Minsoo Kim et al.   BIOTECHNOLOGY AND BIOENGINEERING

DNA methylation contributes to loss in productivity of monoclonal antibody-producing CHO cell lines

(2010) Yuansheng Yang et al.   JOURNAL OF BIOTECHNOLOGY

A study of monoclonal antibody-producing CHO cell lines: What makes a stable high producer?

(2008) Janet Chusainow et al.   BIOTECHNOLOGY AND BIOENGINEERING

Homogeneity and persistence of transgene expression by omitting antibiotic selection in cell line isolation

(2008) W. L. Kaufman et al.   NUCLEIC ACIDS RESEARCH