Large-scale production of red blood cells from stem cells: What are the technical challenges ahead?
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Large-scale production of red blood cells from stem cells: What are the technical challenges ahead?
Authors
Keywords
-
Journal
Biotechnology Journal
Volume 9, Issue 1, Pages 28-38
Publisher
Wiley
Online
2013-10-23
DOI
10.1002/biot.201200368
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation
- (2013) B. W. Smith et al. BLOOD
- Advances in improving mammalian cells metabolism for recombinant protein production
- (2013) Claudia Altamirano et al. ELECTRONIC JOURNAL OF BIOTECHNOLOGY
- Establishment of Immortalized Human Erythroid Progenitor Cell Lines Able to Produce Enucleated Red Blood Cells
- (2013) Ryo Kurita et al. PLoS One
- In VitroLarge Scale Production of Human Mature Red Blood Cells from Hematopoietic Stem Cells by Coculturing with Human Fetal Liver Stromal Cells
- (2013) Jiafei Xi et al. Biomed Research International
- Maturing reticulocytes internalize plasma membrane in glycophorin A-containing vesicles that fuse with autophagosomes before exocytosis
- (2012) R. E. Griffiths et al. BLOOD
- The Potential of Stem Cells as an In Vitro Source of Red Blood Cells for Transfusion
- (2012) Anna Rita Migliaccio et al. Cell Stem Cell
- Ex-vivo generation of human red cells for transfusion
- (2012) David J. Anstee et al. CURRENT OPINION IN HEMATOLOGY
- Human induced pluripotent stem cells can reach complete terminal maturation: in vivo and in vitro evidence in the erythropoietic differentiation model
- (2012) L. Kobari et al. HAEMATOLOGICA
- A novel automated bioreactor for scalable process optimisation of haematopoietic stem cell culture
- (2012) E. Ratcliffe et al. JOURNAL OF BIOTECHNOLOGY
- Concise Review: Stem Cell-Derived Erythrocytes as Upcoming Players in Blood Transfusion
- (2012) Ann Zeuner et al. STEM CELLS
- Proof of principle for transfusion of in vitro-generated red blood cells
- (2011) M.-C. Giarratana et al. BLOOD
- Under HEMA conditions, self-replication of human erythroblasts is limited by autophagic death
- (2011) Giovanni Migliaccio et al. BLOOD CELLS MOLECULES AND DISEASES
- Ex-vivo expansion of red blood cells: How real for transfusion in humans?
- (2011) Anna Rita Migliaccio et al. BLOOD REVIEWS
- Red blood cells from induced pluripotent stem cells: hurdles and developments
- (2011) Christelle Mazurier et al. CURRENT OPINION IN HEMATOLOGY
- Design properties of hydrogel tissue-engineering scaffolds
- (2011) Junmin Zhu et al. Expert Review of Medical Devices
- Production of Embryonic and Fetal-Like Red Blood Cells from Human Induced Pluripotent Stem Cells
- (2011) Chan-Jung Chang et al. PLoS One
- Ultra-High-Yield Manufacture of Red Blood Cells from Hematopoietic Stem Cells
- (2011) Nicholas E. Timmins et al. TISSUE ENGINEERING PART C-METHODS
- Compartmental Hollow Fiber Capillary Membrane–Based Bioreactor Technology for In Vitro Studies on Red Blood Cell Lineage Direction of Hematopoietic Stem Cells
- (2011) Greggory J. Housler et al. TISSUE ENGINEERING PART C-METHODS
- Current problems and future directions of transfusion-induced alloimmunization: summary of an NHLBI working group
- (2011) James C. Zimring et al. TRANSFUSION
- Banking of Pluripotent Adult Stem Cells as an Unlimited Source for Red Blood Cell Production: Potential Applications for Alloimmunized Patients and Rare Blood Challenges
- (2011) Thierry Peyrard et al. TRANSFUSION MEDICINE REVIEWS
- Humanized Culture Medium for Clinical Expansion of Human Erythroblasts
- (2010) Giovanni Migliaccio et al. CELL TRANSPLANTATION
- Ex vivo expansion of human HSCs with Sendai virus vector expressing HoxB4 assessed by sheep in utero transplantation
- (2010) Tomoyuki Abe et al. EXPERIMENTAL HEMATOLOGY
- The majority of the in vitro erythroid expansion potential resides in CD34- cells, outweighing the contribution of CD34+ cells and significantly increasing the erythroblast yield from peripheral blood samples
- (2010) E. van den Akker et al. HAEMATOLOGICA
- Red blood cell generation from human induced pluripotent stem cells: perspectives for transfusion medicine
- (2010) H. Lapillonne et al. HAEMATOLOGICA
- Red blood cell production from immortalized progenitor cell line
- (2010) Yukio Nakamura et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- From stem cell to erythroblast: Regulation of red cell production at multiple levels by multiple hormones
- (2010) Harvey Lodish et al. IUBMB LIFE
- Biopharmaceutical benchmarks 2010
- (2010) Gary Walsh NATURE BIOTECHNOLOGY
- Enhanced Production of Red Blood Cells in Suspension by Electrostatic Interactions with Culture Plates
- (2010) Eun Jung Baek et al. TISSUE ENGINEERING PART C-METHODS
- Optimization of chemically defined cell culture media – Replacing fetal bovine serum in mammalian in vitro methods
- (2010) J. van der Valk et al. TOXICOLOGY IN VITRO
- Emerging trends in plasma-free manufacturing of recombinant protein therapeutics expressed in mammalian cells
- (2009) Leopold Grillberger et al. Biotechnology Journal
- Hematopoietic growth factor mimetics: From concept to clinic
- (2009) Michelle Perugini et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Low oxygen concentration as a general physiologic regulator of erythropoiesis beyond the EPO-related downstream tuning and a tool for the optimization of red blood cell production ex vivo
- (2009) Marija Vlaski et al. EXPERIMENTAL HEMATOLOGY
- The potential of human peripheral blood derived CD34+ cells for ex vivo red blood cell production
- (2009) Daniela Boehm et al. JOURNAL OF BIOTECHNOLOGY
- Designing materials to direct stem-cell fate
- (2009) Matthias P. Lutolf et al. NATURE
- Purified Recombinant TAT-Homeobox B4 Expands CD34+ Umbilical Cord Blood and Peripheral Blood Progenitor Cells Ex Vivo
- (2009) Chi-Hung Huang et al. TISSUE ENGINEERING PART C-METHODS
- Blood cell manufacture: current methods and future challenges
- (2009) Nicholas E. Timmins et al. TRENDS IN BIOTECHNOLOGY
- Biologic properties and enucleation of red blood cells from human embryonic stem cells
- (2008) S.-J. Lu et al. BLOOD
- Mimicking stem cell niches to increase stem cell expansion
- (2008) Shara M Dellatore et al. CURRENT OPINION IN BIOTECHNOLOGY
- Ex vivo large-scale generation of human red blood cells from cord blood CD34+ cells by co-culturing with macrophages
- (2008) Akihito Fujimi et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Cell-Free Hemoglobin-Based Blood Substitutes and Risk of Myocardial Infarction and Death
- (2008) Charles Natanson et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The hematopoietic stem cell niche: what are we trying to replicate?
- (2008) Michael Hines et al. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
- Establishment of Mouse Embryonic Stem Cell-Derived Erythroid Progenitor Cell Lines Able to Produce Functional Red Blood Cells
- (2008) Takashi Hiroyama et al. PLoS One
- In vitro clinical-grade generation of red blood cells from human umbilical cord blood CD34+ cells
- (2008) Eun Jung Baek et al. TRANSFUSION
- Upstream processes in antibody production: Evaluation of critical parameters
- (2007) Era Jain et al. BIOTECHNOLOGY ADVANCES
- Hypoxia alters progression of the erythroid program
- (2007) Heather M. Rogers et al. EXPERIMENTAL HEMATOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started