Development of a soft-sensor based on multi-wavelength fluorescence spectroscopy and a dynamic metabolic model for monitoring mammalian cell cultures

Fluorescence-based soft sensor for at situ monitoring of chinese hamster ovary cell cultures

(2014) Kaveh Ohadi et al.   BIOTECHNOLOGY AND BIOENGINEERING

Bioreactor monitoring with spectroscopy and chemometrics: a review

(2012) N. D. Lourenço et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Recent advances in technology supporting biopharmaceutical production from mammalian cells

(2012) M. Butler et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Soft sensors in bioprocessing: A status report and recommendations

(2012) Reiner Luttmann et al.   Biotechnology Journal

A perspective on PSE in pharmaceutical process development and innovation

(2012) Krist V. Gernaey et al.   COMPUTERS & CHEMICAL ENGINEERING

Dynamic metabolic models of CHO cell cultures through minimal sets of elementary flux modes

(2012) F. Zamorano et al.   JOURNAL OF BIOTECHNOLOGY

Experimental validation of an Extended Kalman Filter estimating acetate concentration in E. coli cultures

(2012) L. Dewasme et al.   JOURNAL OF PROCESS CONTROL

Development of a mathematical model for evaluating the dynamics of normal and apoptotic Chinese hamster ovary cells

(2011) Saeideh Naderi et al.   BIOTECHNOLOGY PROGRESS

Metabolic flux analysis of CHO cells at growth and non-growth phases using isotopic tracers and mass spectrometry

(2011) Woo Suk Ahn et al.   METABOLIC ENGINEERING

Prediction of Cell Culture Media Performance Using Fluorescence Spectroscopy

(2010) Paul W. Ryan et al.   ANALYTICAL CHEMISTRY

On-line Estimation in Fed-batch Fermentation Process Using State Space Model and Unscented Kalman Filter

(2010) Jianlin WANG et al.   CHINESE JOURNAL OF CHEMICAL ENGINEERING

Dynamic model of CHO cell metabolism

(2010) Ryan P. Nolan et al.   METABOLIC ENGINEERING

Advances in on-line monitoring and control of mammalian cell cultures: Supporting the PAT initiative

(2009) A.P. Teixeira et al.   BIOTECHNOLOGY ADVANCES

Data-driven Soft Sensors in the process industry

(2009) Petr Kadlec et al.   COMPUTERS & CHEMICAL ENGINEERING

In situ 2D fluorometry and chemometric monitoring of mammalian cell cultures

(2008) Ana P. Teixeira et al.   BIOTECHNOLOGY AND BIOENGINEERING

Feast or famine: autophagy control and engineering in eukaryotic cell culture

(2008) Matthew P Zustiak et al.   CURRENT OPINION IN BIOTECHNOLOGY