Molecular farming in tobacco hairy roots by triggering the secretion of a pharmaceutical antibody

The Endodermis

(2013) Niko Geldner   Annual Review of Plant Biology

Target Product Selection - Where Can Molecular Pharming Make the Difference?

(2013) Mathew Paul et al.   CURRENT PHARMACEUTICAL DESIGN

Molecular Farming of Pharmaceutical Proteins Using Plant Suspension Cell and Tissue Cultures

(2013) Stefan Schillberg et al.   CURRENT PHARMACEUTICAL DESIGN

Optimization of BY-2 cell suspension culture medium for the production of a human antibody using a combination of fractional factorial designs and the response surface method

(2013) Nikolay Vasilev et al.   PLANT BIOTECHNOLOGY JOURNAL

Monoclonal tobacco cell lines with enhanced recombinant protein yields can be generated from heterogeneous cell suspension cultures by flow sorting

(2012) Janina Kirchhoff et al.   PLANT BIOTECHNOLOGY JOURNAL

GMP issues for recombinant plant-derived pharmaceutical proteins

(2011) Rainer Fischer et al.   BIOTECHNOLOGY ADVANCES

Green factory: Plants as bioproduction platforms for recombinant proteins

(2011) Jianfeng Xu et al.   BIOTECHNOLOGY ADVANCES

Pivotal trial with plant cell-expressed recombinant glucocerebrosidase, taliglucerase alfa, a novel enzyme replacement therapy for Gaucher disease

(2011) A. Zimran et al.   BLOOD

Comprehensive characterization of two different Nicotiana tabacum cell lines leads to doubled GFP and HA protein production by media optimization

(2011) David A. Ullisch et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Lateral root initiation: one step at a time

(2011) Ive De Smet   NEW PHYTOLOGIST

Optimal nitrogen supply as a key to increased and sustained production of a monoclonal full-size antibody in BY-2 suspension culture

(2010) T. Holland et al.   BIOTECHNOLOGY AND BIOENGINEERING

Success stories in molecular farming-a brief overview

(2010) Loïc Faye et al.   PLANT BIOTECHNOLOGY JOURNAL

Development of rhizosecretion as a production system for recombinant proteins from hydroponic cultivated tobacco

(2009) Pascal M. W. Drake et al.   FASEB JOURNAL

Extensive Dry Ball Milling of Wheat and Rye Bran Leads toin SituProduction of Arabinoxylan Oligosaccharides through Nanoscale Fragmentation

(2009) Valerie Van Craeyveld et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Change in glycosylation pattern with extension of endoplasmic reticulum retention signal sequence of mouse antibody produced by suspension-cultured tobacco BY2 cells

(2009) Kazuhito Fujiyama et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure

(2008) Richard Strasser et al.   PLANT BIOTECHNOLOGY JOURNAL