Development of a periplasmic FRET screening method for protease inhibitory antibodies

Identification of inhibitory scFv antibodies targeting fibroblast activation protein utilizing phage display functional screens

(2012) Jiping Zhang et al.   FASEB JOURNAL

New opportunities in drug design of metalloproteinase inhibitors: combination between structure–function experimental approaches and systems biology

(2011) Netta Sela-Passwell et al.   Expert Opinion on Drug Discovery

Fluid Shear Stress and Sphingosine 1-Phosphate Activate Calpain to Promote Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) Membrane Translocation and Endothelial Invasion into Three-dimensional Collagen Matrices

(2011) Hojin Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matrix metalloproteinases: protective roles in cancer

(2011) Julie Decock et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A Reverse Binding Motif That Contributes to Specific Protease Inhibition by Antibodies

(2011) Eric L. Schneider et al.   JOURNAL OF MOLECULAR BIOLOGY

Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential

(2011) Netta Sela-Passwell et al.   NATURE MEDICINE

Cross-domain inhibition of TACE ectodomain

(2011) C. J. Tape et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteolytic networks in cancer

(2011) Steven D. Mason et al.   TRENDS IN CELL BIOLOGY

Structural and mechanistic insight into how antibodies inhibit serine proteases

(2010) Rajkumar Ganesan et al.   BIOCHEMICAL JOURNAL

Selective matrix metalloproteinase (MMP) inhibitors in cancer therapy: Ready for prime time?

(2010) Stanley Zucker et al.   CANCER BIOLOGY & THERAPY

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting

(2010) Chrisostomi Gialeli et al.   FEBS Journal

Emerging principles in protease-based drug discovery

(2010) Marcin Drag et al.   NATURE REVIEWS DRUG DISCOVERY

Fifteen years of HIV Protease Inhibitors: raising the barrier to resistance

(2009) Annemarie M.J. Wensing et al.   ANTIVIRAL RESEARCH

Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis

(2009) Laetitia Devy et al.   CANCER RESEARCH

Extracellular Proteases as Targets for Drug Development

(2009) Mare Cudic et al.   CURRENT PROTEIN & PEPTIDE SCIENCE