Anti-cell death engineering of CHO cells: Co-overexpression of Bcl-2 for apoptosis inhibition, Beclin-1 for autophagy induction

Autophagy and apoptosis in Chinese hamster ovary cell culture

(2014) Sun Ok Hwang et al.   Autophagy

Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells

(2014) Ugur Akar et al.   Autophagy

To be or not to be? Examples of incorrect identification of autophagic compartments in conventional transmission electron microscopy of mammalian cells

(2014) Eeva-Liisa Eskelinen   Autophagy

Estimation of autophagy pathway genes for autophagy induction: Overexpression of Atg9A does not induce autophagy in recombinant Chinese hamster ovary cells

(2012) Jae Seong Lee et al.   BIOCHEMICAL ENGINEERING JOURNAL

Rapamycin treatment inhibits CHO cell death in a serum-free suspension culture by autophagy induction

(2012) Jae Seong Lee et al.   BIOTECHNOLOGY AND BIOENGINEERING

Combinatorial engineering of ldh-a and bcl-2 for reducing lactate production and improving cell growth in dihydrofolate reductase-deficient Chinese hamster ovary cells

(2011) Min Kyoung Jeon et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Inhibition of glutamine-dependent autophagy increases t-PA production in CHO Cell fed-batch processes

(2011) Mario A. Jardon et al.   BIOTECHNOLOGY AND BIOENGINEERING

Autophagy and apoptosis of recombinant Chinese hamster ovary cells during fed-batch culture: Effect of nutrient supplementation

(2011) Young Kue Han et al.   BIOTECHNOLOGY AND BIOENGINEERING

Effect of sodium butyrate on autophagy and apoptosis in Chinese hamster ovary cells

(2011) Jae Seong Lee et al.   BIOTECHNOLOGY PROGRESS

The Beclin 1 network regulates autophagy and apoptosis

(2011) R Kang et al.   CELL DEATH AND DIFFERENTIATION

The role of the Atg1/ULK1 complex in autophagy regulation

(2010) Noboru Mizushima   CURRENT OPINION IN CELL BIOLOGY

mTOR regulation of autophagy

(2010) Chang Hwa Jung et al.   FEBS LETTERS

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

In search of an “autophagomometer”

(2009) David C. Rubinsztein et al.   Autophagy

Expression of anti-apoptosis genes alters lactate metabolism of Chinese Hamster Ovary cells in culture

(2009) Haimanti Dorai et al.   BIOTECHNOLOGY AND BIOENGINEERING

BAKandBAXdeletion using zinc-finger nucleases yields apoptosis-resistant CHO cells

(2009) Gregory J. Cost et al.   BIOTECHNOLOGY AND BIOENGINEERING

A Non-canonical MEK/ERK Signaling Pathway Regulates Autophagy via Regulating Beclin 1

(2009) Jianrong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

The autophagy effector Beclin 1: a novel BH3-only protein

(2009) S Sinha et al.   ONCOGENE

Feast or famine: autophagy control and engineering in eukaryotic cell culture

(2008) Matthew P Zustiak et al.   CURRENT OPINION IN BIOTECHNOLOGY

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nutrient deprivation induces autophagy as well as apoptosis in Chinese hamster ovary cell culture

(2007) Sun Ok Hwang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Regulation of Cell Proliferation and Apoptosis in CHO-K1 Cells by the Coexpression of c-Myc and Bcl-2

(2005) Vasiliki Ifandi et al.   BIOTECHNOLOGY PROGRESS