Article
Multidisciplinary Sciences
Can Xiao, Bernat Mir-Simon, Pilar Rivera-Gil
Summary: This article reports a synthetic procedure to obtain stable, reproducible, and robust highly-SERS performing nanocomposites for labeling. The biosensing performance was validated by designing a SERS-based detection assay model for SARS-CoV-2, with a detection limit below 10 ng/mL.
SCIENTIFIC REPORTS
(2022)
Article
Food Science & Technology
Sumeyye Yilmaz-Karaog, Beguem Gurel-Gokmen, Tugba Tunali-Akbay
Summary: This study aimed to compare the efficiency of lactase immobilized PCL/SF-based nanofiber and nitrocellulose membrane in preparing lactose-reduced milk. The results showed that the lactase immobilized nitrocellulose membrane had a higher lactose hydrolysis efficiency than the lactase immobilized PCL/SF-based nanofiber.
Article
Multidisciplinary Sciences
Nadia Hamzawy, Tamer S. Mahmoud, Iman El-Mahallawi, Mahmoud Khedr, Tarek Khalifa
Summary: Thermal drilling is a chip-less hole-forming process affected by rotational speed, feed rate, and cone angle. This study investigates the effect of variations in friction drilling parameters on the surface roughness values and dimensions of a thermally induced bushing. Response surface methodology was used to optimize the drilling parameters, and the experimental results agree with the presented models. The optimal parameters for the lowest surface roughness value are a rotational speed of 1250 rpm, a feed rate of 200 mm/min, and a cone angle of 45 degrees.
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
(2023)
Article
Materials Science, Textiles
Abeer Adel Salih, Rozli Zulkifli, Che Husna Azhari
Summary: This study optimized the tensile strength and modulus of Gigantochloa scortechinii bamboo strips fiber through alkali treatment. The results showed that the optimal tensile properties were achieved under specific alkali concentration and soaking time. The model used in this study has a high predictive accuracy.
JOURNAL OF NATURAL FIBERS
(2022)
Article
Engineering, Environmental
Shalini Thakkar, Jing Liu, Ludovic F. Dumee, Braj Raj Singh, Shruti Shukla, Wenrong Yang
Summary: Arsenic contamination poses a global threat to human lives, necessitating the development of better detection platforms. This study utilizes the natural biomimetic interaction between thiol-rich ligands and arsenic ions, along with nanoarchitecture, to fabricate a bioreceptor probe capable of visual colorimetric response for arsenic detection.
JOURNAL OF WATER PROCESS ENGINEERING
(2022)
Article
Chemistry, Physical
Romain Rouxel, Michele Diego, Paolo Maioli, Noelle Lascoux, Fabien Vialla, Francesco Rossella, Francesco Banfi, Fabrice Vallee, Natalia Del Fatti, Aurelien Crut
Summary: When a metal nanoparticle absorbs light, it undergoes a series of relaxation processes that lead to transient modifications in its optical response. By using time-resolved spectroscopy experiments, it was shown that the transient optical response could be attributed to internal thermalization processes within the nanoparticle, and the effects of electron and ionic lattice heating were quantitatively studied. The study demonstrated the possibility of selectively probing electronic or lattice dynamics by choosing specific probe wavelengths, and showed that the timedependent spectral shape of transient extinction cross-section changes was successively dominated by electron and lattice heating effects.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Environmental Sciences
Wei-Hsin Chen, Che-Ming Chang, Justus Kavita Mutuku, Su Shiung Lam, Wen-Jhy Lee
Summary: The deposition phenomenon of microparticle and SAR-CoV-2 laced bioaerosol in human airways is studied by Taguchi methods and response surface methodology. The combination of 30 L min-1, 5 μm, 200 μg center dot puff-1 has the highest deposition fraction. The low deposition fraction of bioaerosols reduces the probability of SAR-CoV-2 virus transmission.
ENVIRONMENTAL RESEARCH
(2021)
Article
Chemistry, Multidisciplinary
Wen-Qi Chen, Ying-Qi Yu, Ling Cao, Miao-Miao Yin, Yi Liu, Feng-Lei Jiang
Summary: The study designed and constructed competitive, noncompetitive, and uncompetitive inhibitors using enzymes with different surface charges and gold nanoparticles with different surface ligands and particle sizes. It is the first time that an uncompetitive nano inhibitor has been discovered.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Applied
Benediktas Brasiunas, Anton Popov, Arunas Ramanavicius, Almira Ramanaviciene
Summary: A colorimetric sensor based on a redox reaction between AuCl4- ions and reducing sugars was developed, with different sugars showing varied reaction rates and LOD values. The sensitivity of the sensor can be enhanced by prolonging the reaction time, and the linear range for different sugars differs, with distinct LOQ values observed.
Article
Physics, Multidisciplinary
Vineet Ankit, Vineet Kumar, Amit Kumar Yadav, Gaurav Gautam, Kamalesh Kumar Singh, Sunil Mohan
Summary: The study focuses on predicting the tribological performance of Cu-Gr-TiC composites and its correlation with surface topography. Cu-Gr composites reinforced with TiC ceramic particles were prepared using powder metallurgy. The evaluation included microstructure, mechanical characteristics, and dry sliding wear behavior. Response surface methodology (RSM) was used for wear behavior optimization and a quadratic model was suggested for predicting tribological properties. The study demonstrates the significance of RSM in predicting and optimizing tribological properties.
Article
Biochemistry & Molecular Biology
Ilia Goemaere, Deep Punj, Aranit Harizaj, Jessica Woolston, Sofie Thys, Karen Sterck, Stefaan C. De Smedt, Winnok H. De Vos, Kevin Braeckmans
Summary: Photoporation is a gentle and efficient method for transfecting cells, and response surface methodology (RSM) proves to be a valuable approach for optimizing the photoporation procedure. By varying PDNP size, concentration, and laser fluence, the RSM designs successfully identified an optimal delivery yield and revealed a strong dependence on PDNP size.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Spectroscopy
Linlin Chen, Tianjiao Fan, Wei Li, Jiaqi Song, Jiaxin Zhang, Ling Wang, Ke Han
Summary: A novel and rapid fluorescence method for nitrite determination has been developed by utilizing the interaction between gold nanoparticles and methanobactin (Mb) fluorescence, demonstrating great practical application prospects for nitrite analysis in real samples such as milk, ham sausage, and leaf mustard.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Multidisciplinary
Guillermo S. Moreno-Pescador, Dunya S. Aswad, Christoffer D. Florentsen, Azra Bahadori, Mohammad R. Arastoo, Helena Maria D. Danielsen, Anne Sofie B. Heitmann, Theresa L. Boye, Jesper Nylandsted, Lene B. Oddershede, Poul Martin Bendix
Summary: A study demonstrates the creation of nanoscopic holes in the cell plasma membrane using laser-induced heating of gold nanostructures, which allows for the identification of molecular components involved in membrane repair. Annexin V is found to reshape the edges surrounding the membrane holes, as evidenced by experiments using model membranes. The thermoplasmonic method provides new insights into how cells respond to photothermal treatment.
Article
Food Science & Technology
Zaheer Ahmed, Tahir Mehmood, Ifra Ferheen, Abdul Wasim Noori, Majid Almansouri, Muhammad Waseem
Summary: The primary objective of this study was to optimize the production of exopolysaccharide (EPS) produced by L. kefiranofaciens ZW3 using response surface methodology (RSM). The effects of lactose, tryptophan, and pH on EPS production were studied using Central Composite Design (CCD). RSM analysis showed a good fit for the second-order polynomial model, with lactose, tryptophan, and pH values of 0.36%, 0.23%, and 5.19, respectively, being the optimal conditions. The study confirms the adequacy of the model and suggests that it could help enhance EPS production for various industrial applications.
INTERNATIONAL JOURNAL OF FOOD PROPERTIES
(2023)
Article
Construction & Building Technology
Hany A. Dahish, Ahmed D. Almutairi
Summary: This paper investigates the effect of elevated temperatures on the compressive strength of nano-modified concrete mixtures. Predictive models were constructed using response surface methodology to optimize the compressive strength of modified concrete with nano-silica and/or nano-clay as partial cement substitutions. Experimental data from 208 cubic specimens were used to assess the influence of curing ages and various temperatures on the compressive strength. The developed models were validated and showed good agreement with the experimental data.
CASE STUDIES IN CONSTRUCTION MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Juan M. Garcia-Garfido, Javier Enriquez, Ignacio Chi-Duran, Ivan Jara, Leonardo Vivas, Federico J. Hernandez, Felipe Herrera, Dinesh P. Singh
Summary: By studying and controlling the solvothermal synthesis process, large-area MOF single crystals were successfully obtained, and a reaction mechanism for crystal formation was proposed. The nucleation and growth process of MIRO-101 were investigated through ex situ crystal image analysis, deepening the understanding of MOF growth processes in solution.
Article
Chemistry, Multidisciplinary
Gerzon E. Delgado, Giovanni Marin, Syed Wasim, Carlos Rincon, Dinesh P. Singh
Summary: This work focuses on the preparation and structural characterization of the semiconductor Cu3In5 square Se-9, which crystallizes with tetragonal symmetry and consists of distorted CuSe4 and InSe4 tetrahedra. The compound is related to p-type CuInSe2 and n-type CuIn3Se5 semiconductor compounds used in high-efficiency solar cells.
ORBITAL-THE ELECTRONIC JOURNAL OF CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Renuka Ranjan, Arvind M. Kayastha, Neeraj Sinha
Summary: Researchers conducted preliminary analyses of interactions between amyloid-beta and hydroxyapatite-cholesterol composites, finding that amyloid-beta aggregates only under certain cholesterol concentration conditions in the composites. Solid-state NMR and transmission electron microscopy revealed that the aggregation kinetics of amyloid-beta depend to a certain extent on the exposure and availability of cholesterol surface in the composites.
Article
Energy & Fuels
Leonardo Vivas, Dinesh Pratap Singh
Summary: The study focuses on a new type of active electrode material rGO-Au composite, synthesized in an eco-friendly way. It performs well as a supercapacitor in both three-electrode configuration and coin cell device, showing high specific capacitance and capacity retention, indicating its potential for commercialization.
FRONTIERS IN ENERGY RESEARCH
(2022)
Article
Environmental Sciences
Krishnamoorthy Shanmugaraj, Cristian H. Campos, Ramalinga Viswanathan Mangalaraja, Karuppasamy Nandhini, Radhamanohar Aepuru, Cecilia C. Torres, Dinesh Pratap Singh, Deepak Kumar, Malaichamy Ilanchelian, Ajit Sharma, Dai-Viet N. Vo
Summary: In this study, a halloysite nanotubes catalyst modified with gold nanoparticles was synthesized and its performance was investigated. The results showed that the catalyst exhibited excellent efficiency in degrading dyes and reducing 4NM, with good reusability.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Felipe Lozano-Steinmetz, Victor A. Martinez, Diego A. Vasco, Alonso Sepulveda-Mualin, Dinesh Patrap Singh
Summary: The research focuses on the synthesis and characterization of rGO/Ag aqueous nanofluids, as well as the effects of Ag concentration on thermal conductivity and viscosity. The results show that these nanofluids have potential applications in heat transfer.
Article
Chemistry, Multidisciplinary
Ignacio Chi-Duran, Ruben A. Fritz, Rodrigo Urzua-Leiva, Gloria Cardenas-Jiron, Dinesh Pratap Singh, Felipe Herrera
Summary: Metal-organic frameworks (MOFs) have shown promise for developing next-generation solid-state devices with applications in optics. However, the difficulty in growing large, high-quality MOF single crystals has hindered the implementation of functional devices. By controlling the synthesis conditions, researchers successfully produced large, noncentrosymmetric MOF single crystals with a unique shape and high surface area. These crystals exhibited anisotropic absorption, and the observed size dependence in optical anisotropy was correlated with the preferred orientation of the molecules. This work opens up possibilities for developing optical polarization switches based on MOFs.
Article
Chemistry, Multidisciplinary
Felipe Lozano-Steinmetz, Maria Paz Ramirez-Navarro, Leonardo Vivas, Diego A. Vasco, Dinesh Pratap Singh, Carlos Zambra-Sazo
Summary: Nanofluids, with their improved thermal properties, have gained interest for microchannel heat sink applications. In this study, aqueous nanofluids based on reduced graphene oxide (rGO) decorated with manganese dioxide (MnO2) were prepared. The nanofluids were characterized and their stability, thermal conductivity and rheological behaviors were studied. The results showed that the nanofluids had higher thermal conductivity than water, making them promising alternatives for micro- and millichannel heat sinks.
Article
Biochemistry & Molecular Biology
Avinash Kumar, Vinay Kumar Singh, Arvind M. Kayastha
Summary: This study determined the three-dimensional structure of fenugreek α-amylase using homology modeling and analyzed its molecular basis and mode of action through molecular dynamics simulations and molecular docking. The study identified functional groupings and binding interactions between the enzyme and its substrate maltose. The research provides valuable insights into the atomic-level molecular underpinnings of α-amylase interaction with maltose.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Materials Science, Multidisciplinary
Krishnamoorthy Shanmugaraj, Ramalinga Viswanathan Mangalaraja, Cristian H. Campos, Dinesh Pratap Singh, R. Udayabhaskar, Santiago Bedoya, Radhamanohar Aepuru
Summary: This work reports the synthesis of PtNPs-TiO2NTs catalyst, which exhibits high catalytic efficiency and operational stability in the reduction of AZB dye.
Article
Materials Science, Multidisciplinary
Mahendra Kumar, Chandra Kumar, Deepti Saxena, Dinesh Pratap Singh, Sachin Kumar Sharma, Kapil Saxena
Summary: In this study, Cu2S/CdS thin-film was deposited on an FTO substrate using the spray-pyrolysis technique. Field-emission scanning electron microscopy (FESEM) images showed that the thin-films were mono-dispersed and nearly spherical, with an average size ranging from 50 nm to 100 nm, which increased with increasing temperature. The performance of Sn/Cu2S/CdS/FTO/glass hetrojunction diodes was analyzed through I-V measurement, and parameters such as potential height, leakage current, ideality factor, and series-shunt resistance were calculated using different models. It was observed that the ideality factor decreased from 1.31 to 1.12 and the potential height increased from 0.79 to 0.86 with increasing temperature, according to the thermionic emission model. The estimated values of the diode parameters from these three different methods were in good agreement.
Article
Chemistry, Multidisciplinary
Dinesh Pratap Singh, Leonardo Vivas, Adrian Jara, Daniel Serafini, Juan M. Garcia-Garfido
Summary: The primary focus of current research is the development of new electrode materials for supercapacitor devices, with precise control of material proportions being important for large-scale manufacturing. In this study, CrOOH nanoparticles were synthesized with ascorbic acid and combined with reduced graphene oxide to create highly efficient electrode materials for supercapacitors. The resulting composite material achieved the highest specific capacitance of 199.8 mF cm-2 and demonstrated excellent cyclic stability after 10,000 charge/discharge cycles.
Article
Materials Science, Multidisciplinary
Diego Hidalgo-Rojas, Juan Garcia-Garfido, Javier Enriquez, Ricardo Rojas-Aedo, Robert Alastair Wheatley, Ruben A. Fritz, Dinesh P. Singh, Felipe Herrera, Birger Seifert
Summary: Metal-organic frameworks (MOFs) are promising nonlinear optical materials due to their enhanced stability, and the challenge of producing large single crystals with optimal phase matching conditions has been overcome. Millimeter-sized Zn(3-ptz)(2) uniaxial MOF crystals with high transparency and large birefringence have been synthesized. Strong second-harmonic and third-harmonic generation signals were observed for the first time using femtosecond near-infrared pump pulses. The experiments are in agreement with simulations and demonstrate the potential of MOF single crystals for nonlinear optical devices.
ADVANCED OPTICAL MATERIALS
(2023)
Article
Engineering, Environmental
Shajahan Shanavas, Mohammad Abu Haija, Dinesh Pratap Singh, Tansir Ahamad, Selvaraj Mohana Roopan, Quyet Van Le, Roberto Acevedo, Ponnusamy Munusamy Anbarasan
Summary: In this study, novel 3D/3D/2D-Co3O4/Bi2O3/rGO ternary nanocomposites were successfully synthesized and characterized. The ternary nanocomposite exhibited highly active photocatalytic degradation ability and could be reused multiple times without significant loss in catalytic activity.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Thermodynamics
Victor A. Martinez, Felipe Lozano-Steinmetz, Diego A. Vasco, Paula A. Zapata, Ignacio Chi-Duran, Dinesh Pratap Singh
Summary: Water-based nanofluids prepared with ZnO nanoparticles were characterized for their thermal conductivity, viscosity, and stability. Results showed that nanofluids with 3wt% concentration exhibited improved thermal conductivity and decreased viscosity compared to those with 1wt% concentration. The use of nanofluids in microchannels enhanced heat transfer performance, especially at low Reynolds numbers.
THERMAL SCIENCE AND ENGINEERING PROGRESS
(2021)
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)
