FOXA1: a transcription factor with parallel functions in development and cancer

A Functionally Significant Cross-talk between Androgen Receptor and ErbB2 Pathways in Estrogen Receptor Negative Breast Cancer

(2015) Ali Naderi et al.   NEOPLASIA

Targeting Androgen Receptor in Estrogen Receptor-Negative Breast Cancer

(2011) Min Ni et al.   CANCER CELL

Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer

(2011) Biswajyoti Sahu et al.   EMBO JOURNAL

Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1

(2011) Jessica L L Robinson et al.   EMBO JOURNAL

Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers

(2011) A. A. Serandour et al.   GENOME RESEARCH

High-level expression of forkhead-box protein A1 in metastatic prostate cancer

(2011) Rohit K Jain et al.   HISTOPATHOLOGY

Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA

(2011) Dong Wang et al.   NATURE

Genome profiling of ERBB2-amplified breast cancers

(2010) Fabrice Sircoulomb et al.   BMC CANCER

ErbB3 Binding Protein 1 Represses Metastasis-Promoting Gene Anterior Gradient Protein 2 in Prostate Cancer

(2010) Y. Zhang et al.   CANCER RESEARCH

Prognosis of Hormone-Dependent Breast Cancers: Implications of the Presence of Dysfunctional Transcriptional Networks Activated by Insulin via the Immune Transcription Factor T-bet

(2010) K. McCune et al.   CANCER RESEARCH

Loss of FOXA1/2 Is Essential for the Epithelial-to-Mesenchymal Transition in Pancreatic Cancer

(2010) Y. Song et al.   CANCER RESEARCH

The FoxA factors in organogenesis and differentiation

(2010) Klaus H Kaestner   CURRENT OPINION IN GENETICS & DEVELOPMENT

FOXA1 is an essential determinant of ER  expression and mammary ductal morphogenesis

(2010) G. M. Bernardo et al.   DEVELOPMENT

Copy number and targeted mutational analysis reveals novel somatic events in metastatic prostate tumors

(2010) C. M. Robbins et al.   GENOME RESEARCH

CCCTC-binding Factor Acts Upstream of FOXA1 and Demarcates the Genomic Response to Estrogen

(2010) Yu Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Foxa1 and Foxa2 positively and negatively regulate Shh signalling to specify ventral midbrain progenitor identity

(2010) Yannis E. Mavromatakis et al.   MECHANISMS OF DEVELOPMENT

Foxa1 and Foxa2 Maintain the Metabolic and Secretory Features of the Mature β-Cell

(2010) Nan Gao et al.   MOLECULAR ENDOCRINOLOGY

FOXA1 is a key determinant of estrogen receptor function and endocrine response

(2010) Antoni Hurtado et al.   NATURE GENETICS

Up-regulation of the HSP72 by Foxa1 in MCF-7 human breast cancer cell line

(2009) Lan Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Gene expression of forkhead transcription factors in the normal and diseased human prostate

(2009) Leonie van der Heul-Nieuwenhuijsen et al.   BJU INTERNATIONAL

Genome-Wide Promoter Analysis of the SOX4 Transcriptional Network in Prostate Cancer Cells

(2009) C. D. Scharer et al.   CANCER RESEARCH

Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer

(2009) Qianben Wang et al.   CELL

Role of Foxa1 in regulation of bcl2 expression during oxidative-stress-induced apoptosis in A549 type II pneumocytes

(2009) Lan Song et al.   CELL STRESS & CHAPERONES

FOXA1 Is a Potential Oncogene in Anaplastic Thyroid Carcinoma

(2009) C. Nucera et al.   CLINICAL CANCER RESEARCH

Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development

(2009) Wei Lin et al.   DEVELOPMENTAL BIOLOGY

ChIP-Seq of ERα and RNA polymerase II defines genes differentially responding to ligands

(2009) Willem-Jan Welboren et al.   EMBO JOURNAL

Foxa1 and Foxa2 Control the Differentiation of Goblet and Enteroendocrine L- and D-Cells in Mice

(2009) Diana Z. Ye et al.   GASTROENTEROLOGY

Histone H2A.Z is essential for estrogen receptor signaling

(2009) N. Gevry et al.   GENES & DEVELOPMENT

Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers

(2009) J. Eeckhoute et al.   GENOME RESEARCH

A Role for Forkhead Box A1 in Acute Lung Injury

(2009) Lan Song et al.   INFLAMMATION

Foxa1 and Foxa2 regulate bile duct development in mice

(2009) Zhaoyu Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Expression of Forkhead-box protein A1, a marker of luminal A type breast cancer, parallels low Oncotype DX 21-gene recurrence scores

(2009) Foluso O Ademuyiwa et al.   MODERN PATHOLOGY

Histone Deacetylase 7 and FoxA1 in Estrogen-Mediated Repression of RPRM

(2009) S. Malik et al.   MOLECULAR AND CELLULAR BIOLOGY

FoxA1 Binding Directs Chromatin Structure and the Functional Response of a Glucocorticoid Receptor-Regulated Promoter

(2009) S. Belikov et al.   MOLECULAR AND CELLULAR BIOLOGY

Genetic Alterations and Oncogenic Pathways Associated with Breast Cancer Subtypes

(2009) X. Hu et al.   MOLECULAR CANCER RESEARCH

Upstream Stimulatory Factor 2, a Novel FoxA1-Interacting Protein, Is Involved in Prostate-Specific Gene Expression

(2009) Qian Sun et al.   MOLECULAR ENDOCRINOLOGY

Genome-Wide Dynamics of Chromatin Binding of Estrogen Receptors α and β: Mutual Restriction and Competitive Site Selection

(2009) Tze Howe Charn et al.   MOLECULAR ENDOCRINOLOGY

An oestrogen-receptor-α-bound human chromatin interactome

(2009) Melissa J. Fullwood et al.   NATURE

The evolution of Fox genes and their role in development and disease

(2009) Sridhar Hannenhalli et al.   NATURE REVIEWS GENETICS

Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties

(2009) C Coulouarn et al.   ONCOGENE

A FOXA1-binding enhancer regulates Hoxb13 expression in the prostate gland

(2009) R. P. McMullin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Enhancers at the Gene-Poor 8q24 Cancer-Linked Locus

(2009) Li Jia et al.   PLoS Genetics

Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq

(2009) Mehdi Motallebipour et al.   GENOME BIOLOGY

Forkhead box transcription factors Foxa1 and Foxa2 are important regulators of Muc2 mucin expression in intestinal epithelial cells

(2008) Maria van der Sluis et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hepatocyte nuclear factor-3 alpha (HNF-3α) negatively regulates androgen receptor transactivation in prostate cancer cells

(2008) Hyun Joo Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CCCTC-Binding Factor Confines the Distal Action of Estrogen Receptor

(2008) Chang S. Chan et al.   CANCER RESEARCH

Estrogen Induces Repression of the Breast Cancer and Salivary Gland Expression Gene in an Estrogen Receptor   Dependent Manner

(2008) N. Bretschneider et al.   CANCER RESEARCH

FoxA1 Translates Epigenetic Signatures into Enhancer-Driven Lineage-Specific Transcription

(2008) Mathieu Lupien et al.   CELL

Forkhead-box A1 (FOXA1) expression in breast cancer and its prognostic significance

(2008) Hany Onsy Habashy et al.   EUROPEAN JOURNAL OF CANCER

Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development

(2008) N. Gao et al.   GENES & DEVELOPMENT

Basal-Like Breast Cancer: A Critical Review

(2008) Emad A. Rakha et al.   JOURNAL OF CLINICAL ONCOLOGY

Unique ERα Cistromes Control Cell Type-Specific Gene Regulation

(2008) Susan A. Krum et al.   MOLECULAR ENDOCRINOLOGY

Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress

(2008) Irina M Bochkis et al.   NATURE MEDICINE

Genomic Androgen Receptor-Occupied Regions with Different Functions, Defined by Histone Acetylation, Coregulators and Transcriptional Capacity

(2008) Li Jia et al.   PLoS One

Dissociation of Epithelial and Neuroendocrine Carcinoma Lineages in the Transgenic Adenocarcinoma of Mouse Prostate Model of Prostate Cancer

(2007) Teresa Chiaverotti et al.   AMERICAN JOURNAL OF PATHOLOGY

FoxA1 as a lineage-specific oncogene in luminal type breast cancer

(2007) Noritaka Yamaguchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS