Perspective: Sloppiness and emergent theories in physics, biology, and beyond

Efficient Inference of Parsimonious Phenomenological Models of Cellular Dynamics Using S-Systems and Alternating Regression

(2015) Bryan C. Daniels et al.   PLoS One

Model Reduction by Manifold Boundaries

(2014) Mark K. Transtrum et al.   PHYSICAL REVIEW LETTERS

There is More Than One Way to Model an Elephant. Experiment-Driven Modeling of the Actin Cytoskeleton

(2013) Jonathon A. Ditlev et al.   BIOPHYSICAL JOURNAL

The evolutionary origins of modularity

(2013) J. Clune et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Parameter Space Compression Underlies Emergent Theories and Predictive Models

(2013) B. B. Machta et al.   SCIENCE

Optimal experiment selection for parameter estimation in biological differential equation models

(2012) Mark K Transtrum et al.   BMC BIOINFORMATICS

Riemann manifold Langevin and Hamiltonian Monte Carlo methods

(2011) Mark Girolami et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Comment on “Sloppy models, parameter uncertainty, and the role of experimental design”

(2011) Ricky Chachra et al.   Molecular BioSystems

Practical limits for reverse engineering of dynamical systems: a statistical analysis of sensitivity and parameter inferability in systems biology models

(2011) Kamil Erguler et al.   Molecular BioSystems

Archetypal analysis for machine learning and data mining

(2011) Morten Mørup et al.   NEUROCOMPUTING

Geometry of nonlinear least squares with applications to sloppy models and optimization

(2011) Mark K. Transtrum et al.   PHYSICAL REVIEW E

Sloppy models, parameter uncertainty, and the role of experimental design

(2010) Joshua F. Apgar et al.   Molecular BioSystems

Why are Nonlinear Fits to Data so Challenging?

(2010) Mark K. Transtrum et al.   PHYSICAL REVIEW LETTERS

Identification of neutral biochemical network models from time series data

(2009) Marco Vilela et al.   BMC Systems Biology

Matrix Factorization Techniques for Recommender Systems

(2009) Yehuda Koren et al.   COMPUTER

A multi-time-scale analysis of chemical reaction networks: I. Deterministic systems

(2009) Chang Hyeong Lee et al.   JOURNAL OF MATHEMATICAL BIOLOGY

Sloppiness, robustness, and evolvability in systems biology

(2008) Bryan C Daniels et al.   CURRENT OPINION IN BIOTECHNOLOGY

What is principal component analysis?

(2008) Markus Ringnér   NATURE BIOTECHNOLOGY

Model reduction of interconnected linear systems

(2008) H. Sandberg et al.   OPTIMAL CONTROL APPLICATIONS & METHODS