Interaction of Aβ(25-35) fibrillation products with mitochondria: Effect of small-molecule natural products

Transient disturbances in contextual fear memory induced by Aβ(25–35) in rats are accompanied by cholinergic dysfunction

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Estradiol prevents olfactory dysfunction induced by A-β 25–35 injection in hippocampus

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Mitochondrial membrane permeabilization upon interaction with lysozyme fibrillation products: Role of mitochondrial heterogeneity

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The Role of Natural Products in the Discovery of New Drug Candidates for the Treatment of Neurodegenerative Disorders II: Alzheimers Disease

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Aβ Toxicity in Alzheimer's Disease

(2012) Virve Cavallucci et al.   MOLECULAR NEUROBIOLOGY

Palmitoylethanolamide Protects Against the Amyloid-β25-35-Induced Learning and Memory Impairment in Mice, an Experimental Model of Alzheimer Disease

(2012) Giuseppe D'Agostino et al.   NEUROPSYCHOPHARMACOLOGY

Amyloid Precursor Protein Processing and Alzheimer's Disease

(2011) Richard J. O'Brien et al.   Annual Review of Neuroscience

Quercetin inhibits amyloid fibrillation of bovine insulin and destabilizes preformed fibrils

(2011) Jian-Bo Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Membrane and surface interactions of Alzheimer’s Aβ peptide - insights into the mechanism of cytotoxicity

(2011) Thomas L. Williams et al.   FEBS Journal

Membrane Integrity and Amyloid Cytotoxicity: A Model Study Involving Mitochondria and Lysozyme Fibrillation Products

(2011) Ali Akbar Meratan et al.   JOURNAL OF MOLECULAR BIOLOGY

Effect of Phenolic Compounds Against Aβ Aggregation and Aβ-Induced Toxicity in Transgenic C. elegans

(2011) Seema Jagota et al.   NEUROCHEMICAL RESEARCH

Further Evidence on Mitochondrial Targeting of β-Amyloid and Specificity of β-Amyloid-Induced Mitotoxicity in Neurons

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Pre-aggregated Aβ25–35 alters arginine metabolism in the rat hippocampus and prefrontal cortex

(2011) Ping Liu et al.   NEUROSCIENCE

Towards a Pharmacophore for Amyloid

(2011) Meytal Landau et al.   PLOS BIOLOGY

Auxin Biosynthesis and Its Role in Plant Development

(2010) Yunde Zhao   Annual Review of Plant Biology

Potential therapeutic agents against Alzheimer’s disease from natural sources

(2010) So-Young Park   ARCHIVES OF PHARMACAL RESEARCH

Fibrillation of α-lactalbumin: Effect of crocin and safranal, two natural small molecules from Crocus sativus

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Aβ(25–35) as proxyholder for amyloidogenic peptides: In vivo evidence

(2010) Natalia V. Gulyaeva et al.   EXPERIMENTAL NEUROLOGY

Aromatic Small Molecules Remodel Toxic Soluble Oligomers of Amyloid β through Three Independent Pathways

(2010) Ali Reza A. Ladiwala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resveratrol Selectively Remodels Soluble Oligomers and Fibrils of Amyloid Aβ into Off-pathway Conformers

(2010) Ali Reza A. Ladiwala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Docosahexaenoic acid withstands the Aβ25-35-induced neurotoxicity in SH-SY5Y cells

(2010) Michio Hashimoto et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Bringing natural products into the fold – exploring the therapeutic lead potential of secondary metabolites for the treatment of protein-misfolding-related neurodegenerative diseases

(2010) P. Matthew Joyner et al.   NATURAL PRODUCT REPORTS

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

(2010) Jan Bieschke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Indole-3-carbinol improves survival in lupus-prone mice by inducing tandem B- and T-cell differentiation blockades

(2009) Xiao-jie Yan et al.   CLINICAL IMMUNOLOGY

Subcellular and metabolic examination of amyloid-β peptides in Alzheimer disease pathogenesis: Evidence for Aβ25–35

(2009) Yury G. Kaminsky et al.   EXPERIMENTAL NEUROLOGY

The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds

(2009) Sean A. Hudson et al.   FEBS Journal

Effects of Grape Seed-derived Polyphenols on Amyloid β-Protein Self-assembly and Cytotoxicity

(2008) Kenjiro Ono et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-β Membrane Binding and Permeabilization are Distinct Processes Influenced Separately by Membrane Charge and Fluidity

(2008) Pamela T. Wong et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure and Dynamics of a Partially Folded Protein Are Decoupled from Its Mechanism of Aggregation

(2008) Giulia Calloni et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polyphenols as Potential Inhibitors of Amyloid Aggregation and Toxicity:Possible Significance to Alzheimers Disease

(2008) S. Bastianetto et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Isolation of mitochondria from rat brain using Percoll density gradient centrifugation

(2008) Neil R Sims et al.   Nature Protocols