Diverse role of conformational dynamics in carboxypeptidase A-driven peptide and ester hydrolyses: Disclosing the “Perfect Induced Fit” and “Protein Local Unfolding” pathways by altering protein stability

Explicit reformulations of time-dependent solution for a Michaelis–Menten enzyme reaction model

(2010) Marko Goličnik   ANALYTICAL BIOCHEMISTRY

Fluctuations in Biological and Bioinspired Electron-Transfer Reactions

(2010) Spiros S. Skourtis et al.   Annual Review of Physical Chemistry

Multiple Mechanisms for Elongation Processivity within the ReconstitutedTetrahymenaTelomerase Holoenzyme

(2010) Bosun Min et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thermal Unfolding Kinetics of Ubiquitin in the Microsecond-to-Second Time Range Probed by Tyr-59 Fluorescence

(2010) Melinda Noronha et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Catalysis of Carboxypeptidase A: Promoted-Water versus Nucleophilic Pathways

(2010) Shanshan Wu et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Influence of Osmolytes and Denaturants on the Structure and Enzyme Activity of α-Chymotrypsin

(2010) Pankaj Attri et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Role of conformation transitions in adenylate kinase

(2010) Martin Karplus   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reply to Karplus: Conformational dynamics have no role in the chemical step

(2010) Shina C. L. Kamerlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinetics of chain motions within a protein-folding intermediate

(2010) H. Neuweiler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fundamental signatures of short- and long-range electron transfer for the blue copper protein azurin at Au/SAM junctions

(2010) D. E. Khoshtariya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A method to describe enzyme-catalyzed reactions by combining steady state and time course enzyme kinetic parameters

(2009) Ryan Walsh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Counteraction of Urea by Trimethylamine N-Oxide Is Due to Direct Interaction

(2009) Filip Meersman et al.   BIOPHYSICAL JOURNAL

Quantum Mechanical/Molecular Mechanical and Density Functional Theory Studies of a Prototypical Zinc Peptidase (Carboxypeptidase A) Suggest a General Acid−General Base Mechanism

(2009) Dingguo Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct observation of ultrafast folding and denatured state dynamics in single protein molecules

(2009) H. Neuweiler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enzyme millisecond conformational dynamics do not catalyze the chemical step

(2009) A. V. Pisliakov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On the origin of the catalytic power of carboxypeptidase A and other metalloenzymes

(2009) Alexandra Vardi Kilshtain et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Energy landscape along an enzymatic reaction trajectory: Hinges or cracks?

(2008) Paul Charles Whitford et al.   HFSP Journal

Role of Induced Fit in Enzyme Specificity: A Molecular Forward/Reverse Switch

(2008) Kenneth A. Johnson   JOURNAL OF BIOLOGICAL CHEMISTRY

QM/MM study on the mechanism of peptide hydrolysis by carboxypeptidase A

(2008) Michelle W.Y. Szeto et al.   JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM