Thiol Redox Chemistry: Role of Protein Cysteine Oxidation and Altered Redox Homeostasis in Allergic Inflammation and Asthma

The glutaredoxin/S-glutathionylation axis regulates interleukin-17A-induced proinflammatory responses in lung epithelial cells in association with S-glutathionylation of nuclear factor κB family proteins

(2014) James D. Nolin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma

(2014) Hector G. Ortega et al.   NEW ENGLAND JOURNAL OF MEDICINE

Deficiency of gp91phoxInhibits Allergic Airway Inflammation

(2013) Carla M. Sevin et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Omalizumab: A Review of its Use in Patients with Severe Persistent Allergic Asthma

(2013) Kate McKeage   DRUGS

Increased glutaredoxin-1 and decreased proteinS-glutathionylation in sputum of asthmatics

(2013) Ine Kuipers et al.   EUROPEAN RESPIRATORY JOURNAL

Dual oxidase regulates neutrophil recruitment in allergic airways

(2013) Sandra Chang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genetic ablation of glutaredoxin-1 causes enhanced resolution of airways hyperresponsiveness and mucus metaplasia in mice with allergic airways disease

(2012) Sidra M. Hoffman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

S-Nitrosylation: Specificity, Occupancy, and Interaction with Other Post-Translational Modifications

(2012) Alicia M. Evangelista et al.   ANTIOXIDANTS & REDOX SIGNALING

Thioredoxin and Thioredoxin Target Proteins: From Molecular Mechanisms to Functional Significance

(2012) Samuel Lee et al.   ANTIOXIDANTS & REDOX SIGNALING

Biochemical pathogenesis of aspirin exacerbated respiratory disease (AERD)

(2012) Arun Narayanankutty et al.   CLINICAL BIOCHEMISTRY

Reactive Oxygen Species-Induced Actin Glutathionylation Controls Actin Dynamics in Neutrophils

(2012) Jiro Sakai et al.   IMMUNITY

Distinct TLR-mediated pathways regulate house dust mite–induced allergic disease in the upper and lower airways

(2012) Ji-Hwan Ryu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial

(2012) Ian D Pavord et al.   LANCET

Increased Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4 Expression Mediates Intrinsic Airway Smooth Muscle Hypercontractility in Asthma

(2011) Amanda Sutcliffe et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Glutathione biochemistry in asthma

(2011) Niki L. Reynaert   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Nox enzymes in allergic airway inflammation

(2011) Albert van der Vliet   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Cytokine/anti-cytokine therapy - novel treatments for asthma?

(2011) Philip M Hansbro et al.   BRITISH JOURNAL OF PHARMACOLOGY

Ozone affects pollen viability and NAD(P)H oxidase release from Ambrosia artemisiifolia pollen

(2011) Stefania Pasqualini et al.   ENVIRONMENTAL POLLUTION

Anti-inflammatory effects of apocynin, an inhibitor of NADPH oxidase, in airway inflammation

(2011) So Yong Kim et al.   IMMUNOLOGY AND CELL BIOLOGY

Thioredoxin in Allergic Inflammation

(2011) Wataru Ito et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Downregulation of glutathione S-transferase pi in asthma contributes to enhanced oxidative stress

(2011) Kathy T. Schroer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Signal transduction by reactive oxygen species

(2011) Toren Finkel   JOURNAL OF CELL BIOLOGY

Drug companies hope to breathe life into asthma pipeline

(2011) Mike May   NATURE MEDICINE

Glutathione Peroxidase 1 Deficiency Attenuates Allergen-Induced Airway Inflammation by Suppressing Th2 and Th17 Cell Development

(2010) Hee Yeon Won et al.   ANTIOXIDANTS & REDOX SIGNALING

IL-17 and IL-22 in atopic allergic disease

(2010) Yuri Souwer et al.   CURRENT OPINION IN IMMUNOLOGY

The many paths to asthma: phenotype shaped by innate and adaptive immunity

(2010) Hye Young Kim et al.   NATURE IMMUNOLOGY

Glutathione Oxidation Is Associated With Airway Macrophage Functional Impairment in Children With Severe Asthma

(2010) Anne M Fitzpatrick et al.   PEDIATRIC RESEARCH

A Brief History of Asthma and Its Mechanisms to Modern Concepts of Disease Pathogenesis

(2010) Stephen T Holgate   Allergy Asthma & Immunology Research

Thioredoxin reduces C-C chemokine-induced chemotaxis of human eosinophils

(2009) N. Kobayashi et al.   ALLERGY

Immunobiology of Asthma

(2009) Qutayba Hamid et al.   Annual Review of Physiology

Thioredoxin suppresses airway inflammation independently of systemic Th1/Th2 immune modulation

(2009) Mie Torii et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Glutathione peroxidase-2 protects from allergen-induced airway inflammation in mice

(2009) A. M. Dittrich et al.   EUROPEAN RESPIRATORY JOURNAL

Deglutathionylation of 2-Cys Peroxiredoxin Is Specifically Catalyzed by Sulfiredoxin

(2009) Ji Won Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE

Endogenous and Exogenous Thioredoxin 1 Prevents Goblet Cell Hyperplasia in a Chronic Antigen Exposure Asthma Model

(2009) Haruki Imaoka et al.   ALLERGOLOGY INTERNATIONAL

Glutathione Transferase P1

(2008) Jiansheng Zhou et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Redox-based regulation of signal transduction: Principles, pitfalls, and promises

(2008) Yvonne M.W. Janssen-Heininger et al.   FREE RADICAL BIOLOGY AND MEDICINE

Novel Role for GlutathioneS-Transferase π

(2008) Danyelle M. Townsend et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulated Protein Denitrosylation by Cytosolic and Mitochondrial Thioredoxins

(2008) M. Benhar et al.   SCIENCE