7-Methoxy-(9H-β-Carbolin-1-il)-(E)-1-Propenoic Acid, a β-Carboline Alkaloid FromEurycoma longifolia, Exhibits Anti-Inflammatory Effects by Activating the Nrf2/Heme Oxygenase-1 Pathway

A new anti-inflammatory β-carboline alkaloid from the hairy-root cultures ofEurycoma longifolia

(2015) Pham Bich Ngoc et al.   NATURAL PRODUCT RESEARCH

Caffeoylglycolic acid methyl ester, a major constituent of sorghum, exhibits anti-inflammatory activity via the Nrf2/heme oxygenase-1 pathway

(2015) Young-Yeon Choo et al.   RSC Advances

Five new quassinoids and cytotoxic constituents from the roots of Eurycoma longifolia

(2014) SeonJu Park et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The anti-inflammatory effect of 3-deoxysappanchalcone is mediated by inducing heme oxygenase-1 via activating the AKT/mTOR pathway in murine macrophages

(2014) Jun-Hyeong Kim et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Transcription Factors NRF2 and NF-κB Are Coordinated Effectors of the Rho Family, GTP-binding Protein RAC1 during Inflammation

(2014) Antonio Cuadrado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NF-κB Inhibitors from Eurycoma longifolia

(2014) Thi Van Anh Tran et al.   JOURNAL OF NATURAL PRODUCTS

Heme Oxygenase-1 As a Target for Drug Discovery

(2013) Roberto Motterlini et al.   ANTIOXIDANTS & REDOX SIGNALING

The emerging role of the Nrf2-Keap1 signaling pathway in cancer

(2013) M. C. Jaramillo et al.   GENES & DEVELOPMENT

Anti-Inflammatory Therapy in Chronic Disease: Challenges and Opportunities

(2013) I. Tabas et al.   SCIENCE

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Malabaricone C suppresses lipopolysaccharide-induced inflammatory responses via inhibiting ROS-mediated Akt/IKK/NF-κB signaling in murine macrophages

(2012) Jungwon Kang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

In vitro Anti-Inflammatory Effects of Beta-Carboline Alkaloids, Isolated from Picrasma quassioides, through Inhibition of the iNOS Pathway

(2012) Feng Zhao et al.   PLANTA MEDICA

Macrophages and Tissue Injury: Agents of Defense or Destruction?

(2011) Debra L. Laskin et al.   Annual Review of Pharmacology and Toxicology

Targeting the Nrf2-Keap1 antioxidant defence pathway for neurovascular protection in stroke

(2011) Alessio Alfieri et al.   JOURNAL OF PHYSIOLOGY-LONDON

NRF2 targeting: a promising therapeutic strategy in chronic obstructive pulmonary disease

(2011) A. Boutten et al.   TRENDS IN MOLECULAR MEDICINE

Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential

(2010) Ananta Paine et al.   BIOCHEMICAL PHARMACOLOGY

Activation of the Integrin Effector Kinase Focal Adhesion Kinase in Cancer Cells Is Regulated by Crosstalk between Protein Kinase C  and the PDZ Adapter Protein mda-9/Syntenin

(2010) C. Hwangbo et al.   CANCER RESEARCH

Tongkat Ali (Eurycoma longifolia Jack): A review on its ethnobotany and pharmacological importance

(2010) Rajeev Bhat et al.   FITOTERAPIA

Inhibition of Transcription Factors by Plant-Derived Compounds and their Implications in Inflammation and Cancer

(2009) J. Rios et al.   CURRENT PHARMACEUTICAL DESIGN

The anti-inflammatory effect of tussilagone, from Tussilago farfara, is mediated by the induction of heme oxygenase-1 in murine macrophages

(2009) Cheol Hwangbo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Heme Oxygenase-1/Carbon Monoxide Pathway Suppresses TLR4 Signaling by Regulating the Interaction of TLR4 with Caveolin-1

(2009) X. M. Wang et al.   JOURNAL OF IMMUNOLOGY

Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis

(2008) Wenge Li et al.   BIOCHEMICAL PHARMACOLOGY

Heme oxygenase-1 mediates the anti-inflammatory effect of Curcumin within LPS-stimulated human monocytes

(2008) Hsien-Yeh Hsu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Pharmacological and Clinical Aspects of Heme Oxygenase

(2008) N. G. Abraham et al.   PHARMACOLOGICAL REVIEWS