Progress toward the clinical application of patient-specific pluripotent stem cells

Role of the Murine Reprogramming Factors in the Induction of Pluripotency

(2009) Rupa Sridharan et al.   CELL

Oct4-Induced Pluripotency in Adult Neural Stem Cells

(2009) Jeong Beom Kim et al.   CELL

Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

(2009) Frank Soldner et al.   CELL

Optimal Timing of Inner Cell Mass Isolation Increases the Efficiency of Human Embryonic Stem Cell Derivation and Allows Generation of Sibling Cell Lines

(2009) Alice E. Chen et al.   Cell Stem Cell

Telomeres Acquire Embryonic Stem Cell Characteristics in Induced Pluripotent Stem Cells

(2009) Rosa M. Marion et al.   Cell Stem Cell

Broader Implications of Defining Standards for the Pluripotency of iPSCs

(2009) George Q. Daley et al.   Cell Stem Cell

Transplantation of Human Embryonic Stem Cell-Derived Photoreceptors Restores Some Visual Function in Crx-Deficient Mice

(2009) Deepak A. Lamba et al.   Cell Stem Cell

Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins

(2009) Dohoon Kim et al.   Cell Stem Cell

Gene Targeting of a Disease-Related Gene in Human Induced Pluripotent Stem and Embryonic Stem Cells

(2009) Jizhong Zou et al.   Cell Stem Cell

Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins

(2009) Hongyan Zhou et al.   Cell Stem Cell

Epigenetic Modifiers: Basic Understanding and Clinical Development

(2009) R. L. Piekarz et al.   CLINICAL CANCER RESEARCH

Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells

(2009) J. Utikal et al.   JOURNAL OF CELL SCIENCE

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs

(2009) Gabsang Lee et al.   NATURE

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

(2009) Keisuke Kaji et al.   NATURE

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

(2009) Knut Woltjen et al.   NATURE

Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells

(2009) Ángel Raya et al.   NATURE

Variation in the safety of induced pluripotent stem cell lines

(2009) Kyoko Miura et al.   NATURE BIOTECHNOLOGY

Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells

(2009) Sarah Eminli et al.   NATURE GENETICS

Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal

(2009) Myriam Hemberger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stem cell-based cell replacement strategies for the central nervous system

(2009) Jason Sharp et al.   NEUROSCIENCE LETTERS

The role of environmental mercury, lead and pesticide exposure in development of amyotrophic lateral sclerosis

(2009) Frank O. Johnson et al.   NEUROTOXICOLOGY

Generation of pluripotent stem cells from patients with type 1 diabetes

(2009) R. Maehr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenotypic correction of murine hemophilia A using an iPS cell-based therapy

(2009) Dan Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of mouse-induced pluripotent stem cells by transient expression of a single nonviral polycistronic vector

(2009) F. Gonzalez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4

(2009) C. A. Lyssiotis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences

(2009) J. Yu et al.   SCIENCE

Induced pluripotent stem cells: current progress and potential for regenerative medicine

(2009) Giovanni Amabile et al.   TRENDS IN MOLECULAR MEDICINE

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

Stem Cells and Drug Discovery: The Beginning of a New Era?

(2008) Lee L. Rubin   CELL

Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency

(2008) Jacob Hanna et al.   CELL

A Combined Chemical and Genetic Approach for the Generation of Induced Pluripotent Stem Cells

(2008) Yan Shi et al.   Cell Stem Cell

Guidelines and Techniques for the Generation of Induced Pluripotent Stem Cells

(2008) Nimet Maherali et al.   Cell Stem Cell

c-Myc Is Dispensable for Direct Reprogramming of Mouse Fibroblasts

(2008) Marius Wernig et al.   Cell Stem Cell

A High-Efficiency System for the Generation and Study of Human Induced Pluripotent Stem Cells

(2008) Nimet Maherali et al.   Cell Stem Cell

Non-Cell-Autonomous Effect of Human SOD1G37R Astrocytes on Motor Neurons Derived from Human Embryonic Stem Cells

(2008) Maria C.N. Marchetto et al.   Cell Stem Cell

Human Embryonic Stem Cell-Derived Motor Neurons Are Sensitive to the Toxic Effect of Glial Cells Carrying an ALS-Causing Mutation

(2008) Francesco Paolo Di Giorgio et al.   Cell Stem Cell

Reprogramming of Pancreatic β Cells into Induced Pluripotent Stem Cells

(2008) Matthias Stadtfeld et al.   CURRENT BIOLOGY

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

(2008) Salima Hacein-Bey-Abina et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases

(2008) Lucia Migliore et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Dissecting direct reprogramming through integrative genomic analysis

(2008) Tarjei S. Mikkelsen et al.   NATURE

Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors

(2008) Jeong Beom Kim et al.   NATURE

Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes

(2008) Trond Aasen et al.   NATURE BIOTECHNOLOGY

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

(2008) Danwei Huangfu et al.   NATURE BIOTECHNOLOGY

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

(2008) Danwei Huangfu et al.   NATURE BIOTECHNOLOGY

Mediators of reprogramming: transcription factors and transitions through mitosis

(2008) Dieter Egli et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Reprogramming of murine and human somatic cells using a single polycistronic vector

(2008) B. W. Carey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors

(2008) K. Okita et al.   SCIENCE

Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons

(2008) J. T. Dimos et al.   SCIENCE

Reprogramming of Neural Progenitor Cells into Induced Pluripotent Stem Cells in the Absence of Exogenous Sox2 Expression

(2008) Sarah Eminli et al.   STEM CELLS

Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette

(2008) Cesar A. Sommer et al.   STEM CELLS

Human Embryonic Stem Cell-Derived Dopaminergic Neurons Reverse Functional Deficit in Parkinsonian Rats

(2007) Dali Yang et al.   STEM CELLS