Astaxanthin prevents pulmonary fibrosis by promoting myofibroblast apoptosis dependent on Drp1-mediated mitochondrial fission

p53 and mitochondrial function in neurons

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Analysing the relationship between lncRNA and protein-coding gene and the role of lncRNA as ceRNA in pulmonary fibrosis

(2014) Xiaodong Song et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Astaxanthin: Sources, Extraction, Stability, Biological Activities and Its Commercial Applications—A Review

(2014) Ranga Ambati et al.   Marine Drugs

CARL lncRNA inhibits anoxia-induced mitochondrial fission and apoptosis in cardiomyocytes by impairing miR-539-dependent PHB2 downregulation

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An Official American Thoracic Society/European Respiratory Society Statement: Update of the International Multidisciplinary Classification of the Idiopathic Interstitial Pneumonias

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New Light Is Shed on the Enigmatic Origin of the Lung Myofibroblast

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Cell Therapy Trials for Lung Diseases: Progress and Cautions

(2013) Daniel J. Weiss et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Astaxanthin inhibits NF-κB and Wnt/β-catenin signaling pathways via inactivation of Erk/MAPK and PI3K/Akt to induce intrinsic apoptosis in a hamster model of oral cancer

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New insights into the function and regulation of mitochondrial fission

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Cytoplasmic Irradiation Results in Mitochondrial Dysfunction and DRP1-Dependent Mitochondrial Fission

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Rhein Protects Pancreatic  -Cells From Dynamin-Related Protein-1-Mediated Mitochondrial Fission and Cell Apoptosis Under Hyperglycemia

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Apoptosis and angiogenesis: an evolving mechanism for fibrosis

(2013) Ariel Johnson et al.   FASEB JOURNAL

Astaxanthin ameliorates lung fibrosis in vivo and in vitro by preventing transdifferentiation, inhibiting proliferation, and promoting apoptosis of activated cells

(2013) Meirong Wang et al.   FOOD AND CHEMICAL TOXICOLOGY

Astaxanthin ameliorates heat stress-induced impairment of blastocyst development In Vitro: –astaxanthin colocalization with and action on mitochondria–

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Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis

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Pim-1 preserves mitochondrial morphology by inhibiting dynamin-related protein 1 translocation

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Dynamics of nucleoid structure regulated by mitochondrial fission contributes to cristae reformation and release of cytochrome c

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An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2

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Cyclosporine A-induced apoptosis in renal tubular cells is related to oxidative damage and mitochondrial fission

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New Insights on Molecular Mechanisms of Renal Aging

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Regulation and Physiologic Functions of GTPases in Mitochondrial Fusion and Fission in Mammals

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A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity

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The role of dimethylarginine dimethylaminohydrolase (DDAH) in pulmonary fibrosis

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Astaxanthin Induces Mitochondria-Mediated Apoptosis in Rat Hepatocellular Carcinoma CBRH-7919 Cells

(2011) Xiao-dong Song et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

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(2011) Catherine S Palmer et al.   EMBO REPORTS

Survivin expression induced by endothelin-1 promotes myofibroblast resistance to apoptosis

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Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

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(2010) C. Vancheri et al.   EUROPEAN RESPIRATORY JOURNAL

miR-30 Regulates Mitochondrial Fission through Targeting p53 and the Dynamin-Related Protein-1 Pathway

(2010) Jincheng Li et al.   PLoS Genetics

Endothelial–Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis

(2009) Naozumi Hashimoto et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Growth-inhibitory effects of the astaxanthin-rich alga Haematococcus pluvialis in human colon cancer cells

(2009) Paola Palozza et al.   CANCER LETTERS

Apoptosis Repressor with Caspase Recruitment Domain Contributes to Chemotherapy Resistance by Abolishing Mitochondrial Fission Mediated by Dynamin-Related Protein-1

(2009) J.-X. Wang et al.   CANCER RESEARCH

Astaxanthin inhibits tumor invasion by decreasing extracellular matrix production and induces apoptosis in experimental rat colon carcinogenesis by modulating the expressions of ERK-2, NFkB and COX-2

(2009) Ponnuraj Nagendraprabhu et al.   INVESTIGATIONAL NEW DRUGS

Astaxanthin: A Novel Potential Treatment for Oxidative Stress and Inflammation in Cardiovascular Disease

(2008) Fredric J. Pashkow et al.   AMERICAN JOURNAL OF CARDIOLOGY

Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

(2008) Ann Cassidy-Stone et al.   DEVELOPMENTAL CELL

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(2008) D.-F. Suen et al.   GENES & DEVELOPMENT

Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat

(2008) Nicolas Picard et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Dual-immunohistochemistry provides little evidence for epithelial–mesenchymal transition in pulmonary fibrosis

(2008) Mizuho Yamada et al.   HISTOCHEMISTRY AND CELL BIOLOGY

A Chemical Inhibitor of DRP1 Uncouples Mitochondrial Fission and Apoptosis

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