DKK3 blocked translocation of β-catenin/EMT induced by hypoxia and improved gemcitabine therapeutic effect in pancreatic cancer Bxpc-3 cell

MACC1 promotes carcinogenesis of colorectal cancer via β-catenin signaling pathway

(2015) Tiantian Zhen et al.   Oncotarget

GSK-3� and Vitamin D Receptor are Involved in �-Catenin and Snail Signaling in High Glucose-Induced Epithelial-Mesenchymal Transition of Mouse Podocytes

(2014) Jia Guo et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Signaling mechanisms of the epithelial-mesenchymal transition

(2014) D. M. Gonzalez et al.   Science Signaling

Bufalin, a component in Chansu, inhibits proliferation and invasion of hepatocellular carcinoma cells

(2013) Dong-Ze Qiu et al.   BMC Complementary and Alternative Medicine

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

DKK3 is a potential tumor suppressor gene in papillary thyroid carcinoma

(2013) De-tao Yin et al.   ENDOCRINE-RELATED CANCER

Triptolide reverses hypoxia-induced epithelial-mesenchymal transition and stem-like features in pancreatic cancer by NF-κB downregulation

(2013) Li Liu et al.   INTERNATIONAL JOURNAL OF CANCER

Epigenetic silencing of the WNT antagonist Dickkopf 3 disrupts normal Wnt/β-catenin signalling and apoptosis regulation in breast cancer cells

(2013) Tingxiu Xiang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Dickkopf-related protein 3 promotes pathogenic stromal remodeling in benign prostatic hyperplasia and prostate cancer

(2013) Christoph Zenzmaier et al.   PROSTATE

Stem Cell Properties in Cell Cultures From Different Stage of Melanoma Progression

(2013) Cristina Magnoni et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Delta like ligand 4 induces impaired chemo-drug delivery and enhanced chemoresistance in pancreatic cancer

(2012) Muxing Kang et al.   CANCER LETTERS

Pancreatic cancer stem cells: Emerging target for designing novel therapy

(2012) Yiwei Li et al.   CANCER LETTERS

Overexpression of Dickkopf-3 induces apoptosis through mitochondrial pathway in human colon cancer

(2012) Zi-Rong Yang   WORLD JOURNAL OF GASTROENTEROLOGY

β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells

(2011) Helena J M Smartt et al.   GUT

Pancreatic cancer

(2011) Audrey Vincent et al.   LANCET

Wnt antagonist DICKKOPF-3 (Dkk-3) induces apoptosis in human renal cell carcinoma

(2011) Koji Ueno et al.   MOLECULAR CARCINOGENESIS

Hypoxia Induces Tumor Aggressiveness and the Expansion of CD133-Positive Cells in a Hypoxia-Inducible Factor-1α-Dependent Manner in Pancreatic Cancer Cells

(2011) Okito Hashimoto et al.   PATHOBIOLOGY

Epithelial to Mesenchymal Transition by TGFβ-1 Induction Increases Stemness Characteristics in Primary Non Small Cell Lung Cancer Cell Line

(2011) Giuseppe Pirozzi et al.   PLoS One

Siva1 suppresses epithelial-mesenchymal transition and metastasis of tumor cells by inhibiting stathmin and stabilizing microtubules

(2011) N. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 -catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness

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Dickkopf3 overexpression inhibits pancreatic cancer cell growthin vitro

(2011) Yu-Mei Gu   WORLD JOURNAL OF GASTROENTEROLOGY

Transcription factors that mediate epithelial–mesenchymal transition lead to multidrug resistance by upregulating ABC transporters

(2011) M Saxena et al.   Cell Death & Disease

Cancer Stem Cells and Epithelial-to-Mesenchymal Transition (EMT)-Phenotypic Cells: Are They Cousins or Twins?

(2011) Dejuan Kong et al.   Cancers

Enhancing chemosensitivity to gemcitabine via RNA interference targeting the catalytic subunits of protein kinase CK2 in human pancreatic cancer cells

(2010) Jan N Kreutzer et al.   BMC CANCER

Analysis of Dickkopf3 interactions with Wnt signaling receptors

(2010) Rei E. I. Nakamura et al.   GROWTH FACTORS

Potentiation of the effect of gemcitabine by emodin in pancreatic cancer is associated with survivin inhibition

(2009) Qingqu Guo et al.   BIOCHEMICAL PHARMACOLOGY

Tumour growth and resistance to gemcitabine of pancreatic cancer cells are decreased by AP-2α overexpression

(2009) N Jonckheere et al.   BRITISH JOURNAL OF CANCER

Malignant progression of invasive tumour cells seen in hypoxia present an accumulation of β-catenin in the nucleus at the tumour front

(2009) Resit Demir et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer

(2008) Atsushi Masamune et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer

(2008) K Kawasaki et al.   CANCER GENE THERAPY

Down-regulation of Inhibition of Differentiation-1 via Activation of Activating Transcription Factor 3 and Smad Regulates REIC/Dickkopf-3-Induced Apoptosis

(2008) Y. Kashiwakura et al.   CANCER RESEARCH

Dkk3, downregulated in cervical cancer, functions as a negative regulator of β-catenin

(2008) Eun-Ju Lee et al.   INTERNATIONAL JOURNAL OF CANCER

Effects of the Proteasome Inhibitor Bortezomib on Gene Expression Profiles of Pancreatic Cancer Cells

(2007) Zhi-Yu Tang et al.   JOURNAL OF SURGICAL RESEARCH