Epigenetic silencing of the WNT antagonist Dickkopf 3 disrupts normal Wnt/β-catenin signalling and apoptosis regulation in breast cancer cells
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Title
Epigenetic silencing of the WNT antagonist Dickkopf 3 disrupts normal Wnt/β-catenin signalling and apoptosis regulation in breast cancer cells
Authors
Keywords
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Journal
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Volume 17, Issue 10, Pages 1236-1246
Publisher
Wiley
Online
2013-07-25
DOI
10.1111/jcmm.12099
References
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Note: Only part of the references are listed.- Expression of the Wnt antagonist Dickkopf-3 is associated with prognostic clinicopathologic characteristics and impairs proliferation and invasion in endometrial cancer
- (2012) Thanh H. Dellinger et al. GYNECOLOGIC ONCOLOGY
- DNA methylation status of REIC/Dkk-3 gene in human malignancies
- (2012) Tatsuro Hayashi et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- The Ubiquitin Peptidase UCHL1 Induces G0/G1 Cell Cycle Arrest and Apoptosis Through Stabilizing p53 and Is Frequently Silenced in Breast Cancer
- (2012) Tingxiu Xiang et al. PLoS One
- Promoter methylation analysis of WNT/β-catenin signaling pathway regulators to detect adenocarcinoma or its precursor lesion of the cervix
- (2011) W.F. van der Meide et al. GYNECOLOGIC ONCOLOGY
- Wnt antagonist DICKKOPF-3 (Dkk-3) induces apoptosis in human renal cell carcinoma
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- The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/β-catenin signaling and silenced in common carcinomas
- (2011) L Li et al. ONCOGENE
- WNT5A antagonizes WNT/β-catenin signaling and is frequently silenced by promoter CpG methylation in esophageal squamous cell carcinoma
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- PLCD1 is a functional tumor suppressor inducing G2/M arrest and frequently methylated in breast cancer
- (2010) Tingxiu Xiang et al. CANCER BIOLOGY & THERAPY
- Epigenetic disruption of the WNT/ß-catenin signaling pathway in human cancers
- (2010) Ying Ying et al. Epigenetics
- Analysis of Dickkopf3 interactions with Wnt signaling receptors
- (2010) Rei E. I. Nakamura et al. GROWTH FACTORS
- Methylation ofDickkopf-3as a prognostic factor in cirrhosis-related hepatocellular carcinoma
- (2010) Bin Yang WORLD JOURNAL OF GASTROENTEROLOGY
- Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer
- (2009) Jürgen Veeck et al. BMC CANCER
- CMTM3, Located at the Critical Tumor Suppressor Locus 16q22.1, Is Silenced by CpG Methylation in Carcinomas and Inhibits Tumor Cell Growth through Inducing Apoptosis
- (2009) Y. Wang et al. CANCER RESEARCH
- Wnt Antagonist Gene DKK2 Is Epigenetically Silenced and Inhibits Renal Cancer Progression through Apoptotic and Cell Cycle Pathways
- (2009) H. Hirata et al. CLINICAL CANCER RESEARCH
- Promoter methylation and mRNA expression of DKK-3 and WIF-1 in hepatocellular carcinoma
- (2009) Zhen Ding et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer
- (2008) H Suzuki et al. BRITISH JOURNAL OF CANCER
- Promoter methylation of the Wnt/β-catenin signaling antagonistDkk-3is associated with poor survival in gastric cancer
- (2008) Jun Yu et al. CANCER
- REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer
- (2008) K Kawasaki et al. CANCER GENE THERAPY
- Epigenetic inactivation of the secreted frizzled-related protein-5 ( SFRP5 ) gene in human breast cancer is associated with unfavorable prognosis
- (2008) Jürgen Veeck et al. CARCINOGENESIS
- WNT5A Exhibits Tumor-Suppressive Activity through Antagonizing the Wnt/ -Catenin Signaling, and Is Frequently Methylated in Colorectal Cancer
- (2008) J. Ying et al. CLINICAL CANCER RESEARCH
- Dkk3, downregulated in cervical cancer, functions as a negative regulator of β-catenin
- (2008) Eun-Ju Lee et al. INTERNATIONAL JOURNAL OF CANCER
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