Decline in muscle strength and running endurance in klotho deficient C57BL/6 mice

Circulating levels of adipokines and IGF-1 are associated with skeletal muscle strength of young and old healthy subjects

(2013) Laura Bucci et al.   BIOGERONTOLOGY

Age-dependent alteration in muscle regeneration: the critical role of tissue niche

(2013) Laura Barberi et al.   BIOGERONTOLOGY

Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy

(2013) Francesco S. Loffredo et al.   CELL

Moderate-intensity treadmill running promotes expansion of the satellite cell pool in young and old mice

(2013) Gabi Shefer et al.   FEBS Journal

Loss of Klotho Contributes to Kidney Injury by Derepression of Wnt/ -Catenin Signaling

(2013) L. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sarcopenia in older adults

(2012) Jeremy D. Walston   CURRENT OPINION IN RHEUMATOLOGY

A Contemporary Atlas of the Mouse Diaphragm

(2012) Pascal Stuelsatz et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

The aged niche disrupts muscle stem cell quiescence

(2012) Joe V. Chakkalakal et al.   NATURE

Sarcopenia: Origins and Clinical Relevance

(2011) Irwin H. Rosenberg   CLINICS IN GERIATRIC MEDICINE

Relationship of low plasma klotho with poor grip strength in older community-dwelling adults: the InCHIANTI study

(2011) Richard D. Semba et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Klotho Inhibits Transforming Growth Factor-β1 (TGF-β1) Signaling and Suppresses Renal Fibrosis and Cancer Metastasis in Mice

(2011) Shigehiro Doi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Skeletal Muscle Satellite Cell

(2011) Zipora Yablonka-Reuveni   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Sarcopenia: An Undiagnosed Condition in Older Adults. Current Consensus Definition: Prevalence, Etiology, and Consequences. International Working Group on Sarcopenia

(2011) Roger A. Fielding et al.   Journal of the American Medical Directors Association

Losartan Restores Skeletal Muscle Remodeling and Protects Against Disuse Atrophy in Sarcopenia

(2011) T. N. Burks et al.   Science Translational Medicine

Evolution of sarcopenia research

(2010) Ian Janssen   Applied Physiology Nutrition and Metabolism

Frailty and muscle metabolism dysregulation in the elderly

(2010) W. J. Evans et al.   BIOGERONTOLOGY

Regulation and dysregulation of fibrosis in skeletal muscle

(2010) Antonio L. Serrano et al.   EXPERIMENTAL CELL RESEARCH

Autophagic-lysosomal pathway functions in the masseter and tongue muscles in the klotho mouse, a mouse model for aging

(2010) Ryo-hei Iida et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Research Resource: Comprehensive Expression Atlas of the Fibroblast Growth Factor System in Adult Mouse

(2010) Klementina Fon Tacer et al.   MOLECULAR ENDOCRINOLOGY

Reduced Satellite Cell Numbers and Myogenic Capacity in Aging Can Be Alleviated by Endurance Exercise

(2010) Gabi Shefer et al.   PLoS One

Relevant use of Klotho in FGF19 subfamily signaling system in vivo

(2010) K.-i. Tomiyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Klotho and aging

(2009) Makoto Kuro-o   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Molecular aging and rejuvenation of human muscle stem cells

(2009) Morgan E. Carlson et al.   EMBO Molecular Medicine

Klotho is a substrate for α-, β- and γ-secretase

(2009) Laura Bloch et al.   FEBS LETTERS

PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification

(2009) Athanasia Spandidos et al.   NUCLEIC ACIDS RESEARCH

Cellular and molecular mechanisms underlying age-related skeletal muscle wasting and weakness

(2008) James G. Ryall et al.   BIOGERONTOLOGY

Age-related muscle dysfunction

(2008) LaDora V. Thompson   EXPERIMENTAL GERONTOLOGY

In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis

(2008) Teruyo Nakatani et al.   FASEB JOURNAL

The Klotho gene family as a regulator of endocrine fibroblast growth factors

(2008) Hiroshi Kurosu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells

(2008) Morgan E. Carlson et al.   NATURE

Sarcopenic obesity: A new category of obesity in the elderly

(2008) Mauro Zamboni et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1

(2008) S.-K. Cha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA