Quinary protein structure and the consequences of crowding in living cells: Leaving the test-tube behind

On the Importance of Hydrodynamic Interactions in Lipid Membrane Formation

(2013) Tadashi Ando et al.   BIOPHYSICAL JOURNAL

Higher-Order Assemblies in a New Paradigm of Signal Transduction

(2013) Hao Wu   CELL

Reduced Native State Stability in Crowded Cellular Environment Due to Protein–Protein Interactions

(2013) Ryuhei Harada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crowding Induced Entropy-Enthalpy Compensation in Protein Association Equilibria

(2013) Young C. Kim et al.   PHYSICAL REVIEW LETTERS

Detection and Characterization of Protein Interactions In Vivo by a Simple Live-Cell Imaging Method

(2013) Oriol Gallego et al.   PLoS One

Long-range protein-water dynamics in hyperactive insect antifreeze proteins

(2013) K. Meister et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary Capacitance and Control of Protein Stability in Protein-Protein Interaction Networks

(2013) Purushottam D. Dixit et al.   PLoS Computational Biology

A Physics-Based Approach of Coarse-Graining the Cytoplasm of Escherichia coli (CGCYTO)

(2012) Qian Wang et al.   BIOPHYSICAL JOURNAL

Changes in Chromatin Compaction During the Cell Cycle Revealed by Micrometer-Scale Measurement of Molecular Flow in the Nucleus

(2012) Elizabeth Hinde et al.   BIOPHYSICAL JOURNAL

Getting RNA and Protein in Phase

(2012) Stephanie C. Weber et al.   CELL

Crowding effects on the small, fast-folding protein λ6–85

(2012) Sharlene Denos et al.   FARADAY DISCUSSIONS

Lattice microbes: High-performance stochastic simulation method for the reaction-diffusion master equation

(2012) Elijah Roberts et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Phase transitions in the assembly of multivalent signalling proteins

(2012) Pilong Li et al.   NATURE

M-Track: detecting short-lived protein-protein interactions in vivo

(2012) Aurora Zuzuarregui et al.   NATURE METHODS

Effects of Molecular Crowding on the Dynamics of Intrinsically Disordered Proteins

(2012) Elio A. Cino et al.   PLoS One

Nonthermal ATP-dependent fluctuations contribute to the in vivo motion of chromosomal loci

(2012) S. C. Weber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular solid-state nuclear magnetic resonance spectroscopy

(2012) M. Renault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein-binding dynamics imaged in a living cell

(2012) Y. Phillip et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein folding rates and thermodynamic stability are key determinants for interaction with the Hsp70 chaperone system

(2012) Ashok Sekhar et al.   PROTEIN SCIENCE

Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons

(2012) K. Xu et al.   SCIENCE

Exploring Weak, Transient Protein–Protein Interactions in Crowded In Vivo Environments by In-Cell Nuclear Magnetic Resonance Spectroscopy

(2011) Qinghua Wang et al.   BIOCHEMISTRY

Incomplete Folding upon Binding Mediates Cdk4/Cyclin D Complex Activation by Tyrosine Phosphorylation of Inhibitor p27 Protein

(2011) Li Ou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modest Protein−Crowder Attractive Interactions Can Counteract Enhancement of Protein Association by Intermolecular Excluded Volume Interactions

(2011) Jonathan Rosen et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Protein Folding Landscapes in the Living Cell

(2011) Simon Ebbinghaus et al.   Journal of Physical Chemistry Letters

Fast, three-dimensional super-resolution imaging of live cells

(2011) Sara A Jones et al.   NATURE METHODS

Optical measurement of cycle-dependent cell growth

(2011) Mustafa Mir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Absolute Protein-Protein Association Rate Constants from Flexible, Coarse-Grained Brownian Dynamics Simulations: The Role of Intermolecular Hydrodynamic Interactions in Barnase-Barstar Association

(2010) Tamara Frembgen-Kesner et al.   BIOPHYSICAL JOURNAL

Attractive Protein-Polymer Interactions Markedly Alter the Effect of Macromolecular Crowding on Protein Association Equilibria

(2010) Ming Jiao et al.   BIOPHYSICAL JOURNAL

Effects of Proteins on Protein Diffusion

(2010) Yaqiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Macromolecular Crowding Remodels the Energy Landscape of a Protein by Favoring a More Compact Unfolded State

(2010) Jiang Hong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein folding stability and dynamics imaged in a living cell

(2010) Simon Ebbinghaus et al.   NATURE METHODS

Structure, function, and folding of phosphoglycerate kinase are strongly perturbed by macromolecular crowding

(2010) Apratim Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diffusion, Crowding & Protein Stability in a Dynamic Molecular Model of the Bacterial Cytoplasm

(2010) Sean R. McGuffee et al.   PLoS Computational Biology

Atomistic Modeling of Macromolecular Crowding Predicts Modest Increases in Protein Folding and Binding Stability

(2009) Sanbo Qin et al.   BIOPHYSICAL JOURNAL

Striking Effects of Hydrodynamic Interactions on the Simulated Diffusion and Folding of Proteins

(2009) Tamara Frembgen-Kesner et al.   Journal of Chemical Theory and Computation

Post-reductionist protein science, or putting Humpty Dumpty back together again

(2009) Lila M Gierasch et al.   Nature Chemical Biology

Crowding Induced Self-Assembly and Enthalpy-Entropy Compensation

(2009) Jack F. Douglas et al.   PHYSICAL REVIEW LETTERS

Cell Growth and Size Homeostasis in Proliferating Animal Cells

(2009) A. Tzur et al.   SCIENCE

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE

Macromolecular Crowding and Confinement: Biochemical, Biophysical, and Potential Physiological Consequences

(2008) Huan-Xiang Zhou et al.   Annual Review of Biophysics

Crowding Effects on Diffusion in Solutions and Cells

(2008) James A. Dix et al.   Annual Review of Biophysics

Simulation-Based Fitting of Protein-Protein Interaction Potentials to SAXS Experiments

(2008) Seung Joong Kim et al.   BIOPHYSICAL JOURNAL

Cell water dynamics on multiple time scales

(2008) E. Persson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation

(2008) M. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On the Contribution of Water-Mediated Interactions to Protein-Complex Stability†

(2007) Dana Reichmann et al.   BIOCHEMISTRY