Synthesis and degradation jointly determine the responsiveness of the cellular proteome

Genome-wide studies of mRNA synthesis and degradation in eukaryotes

(2011) José E. Pérez-Ortín et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Coupled pre-mRNA and mRNA dynamics unveil operational strategies underlying transcriptional responses to stimuli

(2011) A. Zeisel et al.   Molecular Systems Biology

Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast

(2011) C. Miller et al.   Molecular Systems Biology

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Regulatory mechanisms and networks couple the different phases of gene expression

(2011) Orna Dahan et al.   TRENDS IN GENETICS

Major role for mRNA stability in shaping the kinetics of gene induction

(2010) Ran Elkon et al.   BMC GENOMICS

Timing matters

(2009) Edda Klipp   FEBS LETTERS

The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules

(2009) Shengli Hao et al.   NATURE IMMUNOLOGY

Turnover of the Human Proteome: Determination of Protein Intracellular Stability by Dynamic SILAC

(2008) Mary K. Doherty et al.   JOURNAL OF PROTEOME RESEARCH

Recurrent design patterns in the feedback regulation of the mammalian signalling network

(2008) Stefan Legewie et al.   Molecular Systems Biology

Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation

(2008) Ophir Shalem et al.   Molecular Systems Biology

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay

(2008) L. Dolken et al.   RNA

Decoding of Calcium Oscillations by Phosphorylation Cycles: Analytic Results

(2007) Carlos Salazar et al.   BIOPHYSICAL JOURNAL

Coupling and coordination in gene expression processes: a systems biology view

(2007) Suzanne Komili et al.   NATURE REVIEWS GENETICS