Reactive Oxygen Species and Aging in Caenorhabditis elegans: Causal or Casual Relationship?

Antioxidant defense and aging inC. elegans: Is the oxidative damage theory of aging wrong?

(2011) David Gems et al.   CELL CYCLE

Apurinic/apyrimidinic endonuclease 1, p53, and thioredoxin are linked in control of aging in C. elegans

(2010) Andreas Schlotterer et al.   AGING CELL

Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans

(2010) Wen Yang et al.   AGING CELL

The effect of TAT conjugated platinum nanoparticles on lifespan in a nematode Caenorhabditis elegans model

(2010) Juewon Kim et al.   BIOMATERIALS

A modified feeding RNAi method for simultaneous knock-down of more than one gene in Caenorhabditis elegans

(2010) Kyoengwoo Min* et al.   BIOTECHNIQUES

Effects of sod gene overexpression and deletion mutation on the expression profiles of reporter genes of major detoxification pathways in Caenorhabditis elegans

(2010) Patricia Back et al.   EXPERIMENTAL GERONTOLOGY

A role for p53 in mitochondrial stress response control of longevity in C. elegans

(2010) Alessandro Torgovnick et al.   EXPERIMENTAL GERONTOLOGY

The Impact of Whole Genome Sequencing on Model System Genetics: Get Ready for the Ride

(2010) O. Hobert   GENETICS

Decreased Energy Metabolism Extends Life Span in Caenorhabditis elegans Without Reducing Oxidative Damage

(2010) J. M. Van Raamsdonk et al.   GENETICS

The use of FUdR can cause prolonged longevity in mutant nematodes

(2010) Layla Aitlhadj et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Caenorhabditis elegans diet significantly affects metabolic profile, mitochondrial DNA levels, lifespan and brood size

(2010) S.N. Reinke et al.   MOLECULAR GENETICS AND METABOLISM

Cinnamomum cassia Bark in Two Herbal Formulas Increases Life Span in Caenorhabditis elegans via Insulin Signaling and Stress Response Pathways

(2010) Young-Beob Yu et al.   PLoS One

Flavin Adenine Dinucleotide Rescues the Phenotype of Frataxin Deficiency

(2010) Pilar Gonzalez-Cabo et al.   PLoS One

p53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress

(2009) Natascia Ventura et al.   AGING CELL

A High-Throughput Screen for Chemicals that Increase the Lifespan of Caenorhabditis elegans

(2009) Michael Petrascheck et al.   Annals of the New York Academy of Sciences

Mitochondrial Glutathione, a Key Survival Antioxidant

(2009) Montserrat Marí et al.   ANTIOXIDANTS & REDOX SIGNALING

Towards the molecular mechanism of respiratory complex I

(2009) Judy Hirst   BIOCHEMICAL JOURNAL

Is the oxidative stress theory of aging dead?

(2009) Viviana I. Pérez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Ageing in nematodes: do antioxidants extend lifespan in Caenorhabditis elegans?

(2009) Pamela Boon Li Pun et al.   BIOGERONTOLOGY

Caenorhabditis elegans lifespan extension caused by treatment with an orally active ROS-generator is dependent on DAF-16 and SIR-2.1

(2009) Tanja Heidler et al.   BIOGERONTOLOGY

A transfer-less, multi-well liquid culture feeding system for screening small molecules that affect the longevity of Caenorhabditis elegans

(2009) Vanessa K. Fitzgerald et al.   BIOTECHNIQUES

When a theory of aging ages badly

(2009) Jérôme Lapointe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Regulation of the Longevity Response to Temperature by Thermosensory Neurons in Caenorhabditis elegans

(2009) Seung-Jae Lee et al.   CURRENT BIOLOGY

C. elegans as Model for the Study of High Glucose- Mediated Life Span Reduction

(2009) A. Schlotterer et al.   DIABETES

A Pathogenesis Assay UsingSaccharomycescerevisiaeandCaenorhabditiselegansReveals Novel Roles for Yeast AP-1, Yap1, and Host Dual Oxidase BLI-3 in Fungal Pathogenesis

(2009) Charu Jain et al.   EUKARYOTIC CELL

Decline in oxygen consumption correlates with lifespan in long-lived and short-lived mutants of Caenorhabditis elegans

(2009) Tetsuji Shoyama et al.   EXPERIMENTAL GERONTOLOGY

Deceptively simple but simply deceptive -Caenorhabditis eleganslifespan studies: Considerations for aging and antioxidant effects

(2009) Jan Gruber et al.   FEBS LETTERS

Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation

(2009) Erich B. Tahara et al.   FREE RADICAL BIOLOGY AND MEDICINE

[FeFe]-hydrogenase-like gene is involved in the regulation of sensitivity to oxygen in yeast and nematode

(2009) Michihiko Fujii et al.   GENES TO CELLS

Ce-Duox1/BLI-3 Generates Reactive Oxygen Species as a Protective Innate Immune Mechanism in Caenorhabditis elegans

(2009) V. Chavez et al.   INFECTION AND IMMUNITY

Prohibitins and the functional compartmentalization of mitochondrial membranes

(2009) C. Osman et al.   JOURNAL OF CELL SCIENCE

Mutations in the C. elegans Succinate Dehydrogenase Iron–Sulfur Subunit Promote Superoxide Generation and Premature Aging

(2009) Jingzhou Huang et al.   JOURNAL OF MOLECULAR BIOLOGY

Cell Stress and Aging: New Emphasis on Multiplex Resistance Mechanisms

(2009) R. A. Miller   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

SOD-1 Deletions in Caenorhabditis elegans Alter the Localization of Intracellular Reactive Oxygen Species and Show Molecular Compensation

(2009) S. Yanase et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The effect of different ubiquinones on lifespan in Caenorhabditis elegans

(2009) Yu-Ying Yang et al.   MECHANISMS OF AGEING AND DEVELOPMENT

A method for oral administration of hydrophilic substances to Caenorhabditis elegans: Effects of oral supplementation with antioxidants on the nematode lifespan

(2009) Ayumi Shibamura et al.   MECHANISMS OF AGEING AND DEVELOPMENT

C. elegans longevity pathways converge to decrease mitochondrial membrane potential

(2009) Bernard D. Lemire et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Mitochondrial respiratory chain dysfunction variably increases oxidant stress in Caenorhabditis elegans

(2009) Stephen Dingley et al.   MITOCHONDRION

Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans

(2009) Marta Artal-Sanz et al.   NATURE

Subcomplex Iλ Specifically Controls Integrated Mitochondrial Functions in Caenorhabditis elegans

(2009) Marni J. Falk et al.   PLoS One

Molecular and Sensory Basis of a Food Related Two-State Behavior in C. elegans

(2009) Juliette Ben Arous et al.   PLoS One

Mitochondrial generation of free radicals and hypoxic signaling

(2009) Robert O. Poyton et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Deletion of the Mitochondrial Superoxide Dismutase sod-2 Extends Lifespan in Caenorhabditis elegans

(2009) Jeremy M. Van Raamsdonk et al.   PLoS Genetics

A Regulated Response to Impaired Respiration Slows Behavioral Rates and Increases Lifespan in Caenorhabditis elegans

(2009) David Cristina et al.   PLoS Genetics

Altered bacterial metabolism, not coenzyme Q content, is responsible for the lifespan extension in Caenorhabditis elegans fed an Escherichia coli diet lacking coenzyme Q

(2008) Ryoichi Saiki et al.   AGING CELL

Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans

(2008) Michael Morcos et al.   AGING CELL

Redox Signaling Across Cell Membranes

(2008) Aron B. Fisher   ANTIOXIDANTS & REDOX SIGNALING

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Dicarbonyls linked to damage in the powerhouse: glycation of mitochondrial proteins and oxidative stress

(2008) Naila Rabbani et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Dietary restriction by growth in axenic medium induces discrete changes in the transcriptional output of genes involved in energy metabolism inCaenorhabditis elegans

(2008) Natascha Castelein et al.   Biotechnology Journal

Function of reactive oxygen species during animal development: Passive or active?

(2008) Luis Covarrubias et al.   DEVELOPMENTAL BIOLOGY

Modulation of longevity and diapause by redox regulation mechanisms under the insulin-like signaling control in Caenorhabditis elegans

(2008) Yoko Honda et al.   EXPERIMENTAL GERONTOLOGY

Compounds that confer thermal stress resistance and extended lifespan

(2008) Michael G. Benedetti et al.   EXPERIMENTAL GERONTOLOGY

Significant longevity-extending effects of EGCG on Caenorhabditis elegans under stress

(2008) Longze Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans

(2008) R. Doonan et al.   GENES & DEVELOPMENT

Hyperoxia Exposure Induced Hormesis Decreases Mitochondrial Superoxide Radical Levels via Ins/IGF-1 Signaling Pathway in a Long-lived age-1 Mutant of Caenorhabditis elegans

(2008) Sumino YANASE et al.   JOURNAL OF RADIATION RESEARCH

Effects of a potent antioxidant, platinum nanoparticle, on the lifespan of Caenorhabditis elegans

(2008) Juewon Kim et al.   MECHANISMS OF AGEING AND DEVELOPMENT

SOD isoforms play no role in lifespan in ad lib or dietary restricted conditions, but mutational inactivation of SOD-1 reduces life extension by cold

(2008) Kelvin Yen et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Evidence for a Superoxide Permeability Pathway in Endosomal Membranes

(2008) D. R. Mumbengegwi et al.   MOLECULAR AND CELLULAR BIOLOGY

DNA damage and ageing: new-age ideas for an age-old problem

(2008) George A. Garinis et al.   NATURE CELL BIOLOGY

Caenorhabditis elegans mutant allele identification by whole-genome sequencing

(2008) Sumeet Sarin et al.   NATURE METHODS

The art and design of genetic screens: RNA interference

(2008) Michael Boutros et al.   NATURE REVIEWS GENETICS

Identification by machine vision of the rate of motor activity decline as a lifespan predictor in C. elegans

(2008) Ao-Lin Hsu et al.   NEUROBIOLOGY OF AGING

Epigallocatechin Gallate from Green Tea (Camellia sinensis) Increases Lifespan and Stress Resistance inCaenorhabditis elegans

(2008) Sami Abbas et al.   PLANTA MEDICA

A redox-sensitive peroxiredoxin that is important for longevity has tissue- and stress-specific roles in stress resistance

(2008) M. Olahova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Remarkable longevity and stress resistance of nematode PI3K-null mutants

(2007) Srinivas Ayyadevara et al.   AGING CELL

Paraquat Poisonings: Mechanisms of Lung Toxicity, Clinical Features, and Treatment

(2007) R. J. Dinis-Oliveira et al.   CRITICAL REVIEWS IN TOXICOLOGY

Oxidative stress in Caenorhabditis elegans: protective effects of the Omega class glutathione transferase (GSTO-1)

(2007) Cora Burmeister et al.   FASEB JOURNAL