Is adult stem cell aging driven by conflicting modes of chromatin remodeling?

Replicative senescence of mesenchymal stem cells causes DNA-methylation changes which correlate with repressive histone marks

(2016) Anne Schellenberg et al.   Aging-US

DNA Methylation Does Not Stably Lock Gene Expression but Instead Serves as a Molecular Mark for Gene Silencing Memory

(2012) N. J.- M. Raynal et al.   CANCER RESEARCH

Modeling the dynamic epigenome: from histone modifications towards self-organizing chromatin

(2012) Thimo Rohlf et al.   Epigenomics

Stem cell depletion in Hutchinson-Gilford progeria syndrome

(2011) Ylva Rosengardten et al.   AGING CELL

Histone exchange and histone modifications during transcription and aging

(2011) Chandrima Das et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells

(2011) T. Yahata et al.   BLOOD

Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging

(2011) M. T. Bocker et al.   BLOOD

UTX, a Histone H3-Lysine 27 Demethylase, Acts as a Critical Switch to Activate the Cardiac Developmental Program

(2011) Seunghee Lee et al.   DEVELOPMENTAL CELL

A model for mitotic inheritance of histone lysine methylation

(2011) Mo Xu et al.   EMBO REPORTS

Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers

(2011) A. A. Serandour et al.   GENOME RESEARCH

Manifestations and mechanisms of stem cell aging

(2011) Ling Liu et al.   JOURNAL OF CELL BIOLOGY

A review and appraisal of the DNA damage theory of ageing

(2011) Alex A. Freitas et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling

(2011) Yoko Hayashi-Takanaka et al.   NUCLEIC ACIDS RESEARCH

Epigenetic regulation of aging stem cells

(2011) E A Pollina et al.   ONCOGENE

Epigenetic reprogramming in the germline: towards the ground state of the epigenome

(2011) P. Hajkova   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age

(2011) W. W. Pang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Switches, Excitable Responses and Oscillations in the Ring1B/Bmi1 Ubiquitination System

(2011) Lan K. Nguyen et al.   PLoS Computational Biology

Individual fates of mesenchymal stem cells in vitro

(2010) Axel Krinner et al.   BMC Systems Biology

Caloric restriction attenuates age-related changes of DNA methyltransferase 3a in mouse hippocampus

(2010) L. Chouliaras et al.   BRAIN BEHAVIOR AND IMMUNITY

Pro Isomerization in MLL1 PHD3-Bromo Cassette Connects H3K4me Readout to CyP33 and HDAC-Mediated Repression

(2010) Zhanxin Wang et al.   CELL

A phospho/methyl switch at histone H3 regulates TFIID association with mitotic chromosomes

(2010) Radhika A Varier et al.   EMBO JOURNAL

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer

(2010) A. E. Teschendorff et al.   GENOME RESEARCH

Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains

(2010) V. K. Rakyan et al.   GENOME RESEARCH

Gene expression density profiles characterize modes of genomic regulation: Theory and experiment

(2010) Hans Binder et al.   JOURNAL OF BIOTECHNOLOGY

Innovation in gene regulation: The case of chromatin computation

(2010) Sonja J. Prohaska et al.   JOURNAL OF THEORETICAL BIOLOGY

CpG islands influence chromatin structure via the CpG-binding protein Cfp1

(2010) John P. Thomson et al.   NATURE

Chromatin structure and the inheritance of epigenetic information

(2010) Raphaël Margueron et al.   NATURE REVIEWS GENETICS

Partitioning of Histone H3-H4 Tetramers During DNA Replication-Dependent Chromatin Assembly

(2010) M. Xu et al.   SCIENCE

Molecular coupling of DNA methylation and histone methylation

(2010) Hideharu Hashimoto et al.   Epigenomics

The role of epigenetics in aging and age-related diseases

(2009) Vincenzo Calvanese et al.   AGEING RESEARCH REVIEWS

Linking DNA methylation and histone modification: patterns and paradigms

(2009) Howard Cedar et al.   NATURE REVIEWS GENETICS

Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells

(2009) P.-O. Esteve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Asymmetric Strand Segregation: Epigenetic Costs of Genetic Fidelity?

(2009) Diane P. Genereux   PLoS Genetics

Aging and Environmental Exposures Alter Tissue-Specific DNA Methylation Dependent upon CpG Island Context

(2009) Brock C. Christensen et al.   PLoS Genetics

Cell divisions and mammalian aging: integrative biology insights from genes that regulate longevity

(2008) João Pedro de Magalhães et al.   BIOESSAYS

DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity

(2008) Kevin B Dong et al.   EMBO JOURNAL

The intestinal stem cell

(2008) N. Barker et al.   GENES & DEVELOPMENT

Regulation of DNA methylation activity through Dnmt3L promoter methylation by Dnmt3 enzymes in embryonic development

(2008) Ye-Guang Hu et al.   HUMAN MOLECULAR GENETICS

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

(2008) Hannah H. Chang et al.   NATURE

Noise-Driven Stem Cell and Progenitor Population Dynamics

(2008) Martin Hoffmann et al.   PLoS One

Nucleosome destabilization in the epigenetic regulation of gene expression

(2007) Steven Henikoff   NATURE REVIEWS GENETICS