Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging

Stem cell aging: Survival of the laziest?

(2011) Christa Muller-Sieburg et al.   CELL CYCLE

Genome-wide conserved consensus transcription factor binding motifs are hyper-methylated

(2010) Mun-Kit Choy et al.   BMC GENOMICS

General Transcription Factor Binding at CpG Islands in Normal Cells Correlates with Resistance to De novo DNA Methylation in Cancer Cells

(2010) C. Gebhard et al.   CANCER RESEARCH

Distinct Epigenomic Landscapes of Pluripotent and Lineage-Committed Human Cells

(2010) R. David Hawkins et al.   Cell Stem Cell

Stem cells and the aging hematopoietic system

(2010) Isabel Beerman et al.   CURRENT OPINION IN IMMUNOLOGY

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer

(2010) A. E. Teschendorff et al.   GENOME RESEARCH

Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains

(2010) V. K. Rakyan et al.   GENOME RESEARCH

Widespread and tissue specific age-related DNA methylation changes in mice

(2010) S. Maegawa et al.   GENOME RESEARCH

Dynamic changes in the human methylome during differentiation

(2010) L. Laurent et al.   GENOME RESEARCH

Epigenetic control of embryonic stem cell fate

(2010) Nicolaj Strøyer Christophersen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Comprehensive methylome map of lineage commitment from haematopoietic progenitors

(2010) Hong Ji et al.   NATURE

Linking functional decline of telomeres, mitochondria and stem cells during ageing

(2010) Ergün Sahin et al.   NATURE

Targets and dynamics of promoter DNA methylation during early mouse development

(2010) Julie Borgel et al.   NATURE GENETICS

Aging and Chronic Sun Exposure Cause Distinct Epigenetic Changes in Human Skin

(2010) Elke Grönniger et al.   PLoS Genetics

DNA methylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells

(2009) Simone Bork et al.   AGING CELL

DNA Methyltransferase 1 Is Essential for and Uniquely Regulates Hematopoietic Stem and Progenitor Cells

(2009) Jennifer J. Trowbridge et al.   Cell Stem Cell

CpG islands - ‘A rough guide’

(2009) Robert S. Illingworth et al.   FEBS LETTERS

Mammalian cytosine methylation at a glance

(2009) S. K. T. Ooi et al.   JOURNAL OF CELL SCIENCE

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

(2009) Akiko Doi et al.   NATURE GENETICS

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction

(2009) Ann-Marie Bröske et al.   NATURE GENETICS

Pscan: finding over-represented transcription factor binding site motifs in sequences from co-regulated or co-expressed genes

(2009) Federico Zambelli et al.   NUCLEIC ACIDS RESEARCH

Regulation of Stem Cell Pluripotency and Differentiation Involves a Mutual Regulatory Circuit of the Nanog, OCT4, and SOX2 Pluripotency Transcription Factors With Polycomb Repressive Complexes and Stem Cell microRNAs

(2009) Vasundhra Kashyap et al.   STEM CELLS AND DEVELOPMENT

Aging in the lympho-hematopoietic stem cell compartment

(2009) Hartmut Geiger et al.   TRENDS IN IMMUNOLOGY

Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming

(2008) Rudolf Jaenisch et al.   CELL

Promoter CpG Methylation Contributes to ES Cell Gene Regulation in Parallel with Oct4/Nanog, PcG Complex, and Histone H3 K4/K27 Trimethylation

(2008) Shaun D. Fouse et al.   Cell Stem Cell

Stem cell regulation by polycomb repressors: postponing commitment

(2008) Alexandra M Pietersen et al.   CURRENT OPINION IN CELL BIOLOGY

Aging of hematopoietic stem cells is regulated by the stem cell niche

(2008) Wolfgang Wagner et al.   EXPERIMENTAL GERONTOLOGY

Lineage-Specific Polycomb Targets and De Novo DNA Methylation Define Restriction and Potential of Neuronal Progenitors

(2008) Fabio Mohn et al.   MOLECULAR CELL

Polycomb Repressive Complex 2 (PRC2) Restricts Hematopoietic Stem Cell Activity

(2008) Ian J Majewski et al.   PLOS BIOLOGY