Article
Biochemistry & Molecular Biology
Ashley S. Nemec-Bakk, Sarah Niccoli, Caitlund Davidson, Danika Roy, Lisa Stoa, Shayenthiran Sreetharan, Alain Simard, Douglas R. Boreham, Joanna Y. Wilson, T. C. Tai, Simon J. Lees, Neelam Khaper
Summary: The study found that low-dose radiation during late gestation may affect glucose uptake and oxidative stress in female offspring.
Article
Medicine, Research & Experimental
Sanaa A. El-Benhawy, Rasha A. El-Tahan, Sameh F. Nakhla
Summary: The study found that night shift workers had lower levels of melatonin and antioxidant capacity, higher levels of inflammatory markers and cortisol, while workers exposed to radiation had higher levels of melatonin and inflammatory markers, lower levels of cortisol and antioxidant capacity. This indicates that occupational exposure to radiation and night shift work can affect circulating redox and inflammatory biomarkers.
ARCHIVES OF MEDICAL RESEARCH
(2021)
Article
Environmental Sciences
Ming Fu, Chenming Wang, Shiru Hong, Xin Guan, Hua Meng, Yue Feng, Yang Xiao, Yuhan Zhou, Chenliang Liu, Guorong Zhong, Yingqian You, Tianhao Wu, Handong Yang, Xiaomin Zhang, Meian He, Huan Guo
Summary: This study investigated the individual and mixture effect of plasma metals on blood mitochondrial DNA copy number. The results showed that plasma copper, rubidium and titanium were associated with increased blood mitochondrial DNA, and there was a significant mixture effect of all metals on mitochondrial DNA copy number among elderly population.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Amber L. Cathey, Deborah J. Watkins, Zaira Y. Rosario, Carmen Velez, Bhramar Mukherjee, Akram N. Alshawabkeh, Jose F. Cordero, John D. Meeker
Summary: This study investigated the association between phthalate metabolite mixtures and pregnancy outcomes using a longitudinal pregnancy cohort in Puerto Rico. The results showed that exposure to phthalate mixtures was associated with increased risk of preterm birth and highlighted the importance of studying mixtures by fetal sex.
ENVIRONMENTAL HEALTH PERSPECTIVES
(2022)
Article
Multidisciplinary Sciences
Ju Hwan Kim, Dong-Jun Kang, Jun-Sang Bae, Jai Hyuen Lee, Sangbong Jeon, Hyung-Do Choi, Nam Kim, Hyung-Gun Kim, Hak Rim Kim
Summary: Exposure to 1760 MHz RF-EMF induces ROS generation in HaCaT human keratinocytes, leading to activation of MMP and phosphorylation of FoxO3a and ERK1/2 related to skin aging.
SCIENTIFIC REPORTS
(2021)
Article
Environmental Sciences
Gaga Mahai, Yanjian Wan, Aizhen Wang, Xi Qian, Juxiao Li, Ying Li, Wenxin Zhang, Zhenyu He, Yuanyuan Li, Wei Xia, Shunqing Xu
Summary: This study found that urinary concentrations of neonicotinoid insecticides (NNIs) were associated with an increased risk of gestational diabetes mellitus (GDM). Oxidative DNA damage, RNA damage, and lipid peroxidation mediated these associations. Maternal age and pre-pregnancy BMI modified the association between NNIs and GDM.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Biology
Irina S. Bodnar, Evgenia V. Cheban
Summary: The study found that the combined effects of gamma radiation and copper ions reduced the growth rate of duckweed, increased membrane lipid peroxidation, and decreased frond area. However, these factors acted antagonistically on the specific growth rate.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2022)
Article
Engineering, Environmental
Angel Baron-Sola, Margarita Toledo-Basantes, Maria Arana-Gandia, Flor Martinez, Cristina Ortega-Villasante, Tanja Ducic, Ibraheem Yousef, Luis E. Hernandez
Summary: The study used mu SR-FTIR to characterize changes in biomolecules of the green microalga Chlamydomonas reinhardtii caused by Cd and Hg exposure. Metabolic alterations were observed in different biochemical groups in a time-dose dependent manner, with significant changes at higher concentrations. Metals induced intracellular oxidative stress, chloroplast damage, and autophagy, leading to changes in lipid profiles. Mu SR-FTIR spectroscopy proved to be a valuable tool for identifying biochemical alterations in microalgae, providing information that could optimize metal decontamination approaches.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Biochemistry & Molecular Biology
Melis Karabulutoglu, Rosemary Finnon, Lourdes Cruz-Garcia, Mark A. Hill, Christophe Badie
Summary: Haematopoietic bone marrow cells are highly sensitive to ionizing radiation, with potential risks for leukaemia development. This study investigates the effects of oxidative stress and X-ray exposure on murine haematopoietic stem and progenitor cells, revealing significant metabolic deregulation and mitochondrial dysfunctionality.
Article
Physiology
Ying Lu, Jing Gao, Tong Wu, Bo Han, Bingnan Qian, Min Shi, Sa Yang, Qingyun Diao, Chunya Bu, Pingli Dai
Summary: Chlorothalonil and acetamiprid have negative effects on the fitness of honey bee larvae, with the no observed adverse effect concentration (NOAEC) of chlorothalonil and acetamiprid being 4 μg/mL and 2 μg/mL, respectively. Exposure to these pesticides can potentially affect the expression of genes involved in caste development, immune system response, and oxidative stress response in bee larvae.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Santosh Kumar, Shubhankar Suman, Bo-Hyun Moon, Albert J. Fornace Jr, Kamal Datta
Summary: This study reveals that radiation exposure induces long-term oxidative stress in colonic epithelial cells, which is associated with colon carcinogenesis. The NADPH oxidase pathway may play a critical role in propagating this oxidative stress after radiation exposure.
MOLECULAR BIOLOGY REPORTS
(2023)
Article
Nanoscience & Nanotechnology
Kaifang Wang, Xin Ning, Chuanyue Qin, Jianlin Wang, Wenjie Yan, Xin Zhou, Deping Wang, Jimin Cao, Yanlin Feng
Summary: Respiratory exposure to copper oxide nanoparticles can cause acute injuries in major peripheral organs, especially in susceptible individuals.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2022)
Article
Pharmacology & Pharmacy
Sabry M. Attia, Sheikh F. Ahmad, Ahmed Nadeem, Mohamed S. M. Attia, Mushtaq A. Ansari, Mohammed A. Al-Hamamah, Marwa H. Hussein, Alaa A. Alameen, Abdullah F. Alasmari, Saleh A. Bakheet
Summary: Environmental and genetic factors play significant roles in the pathogenesis of autism. This study focused on the susceptibility of BTBR mice, an autism model, to the genotoxic effects of methylmercury and observed DNA repair dysregulation. BTBR mice exposed to methylmercury exhibited increased micronuclei formation, oxidative DNA damage, elevated lipid peroxides, decreased glutathione ratio, and altered expression of DNA repair-related genes. The results suggest that methylmercury exposure exacerbates genotoxic susceptibility and disrupts antioxidant defense and DNA repair in autistic individuals. Regular medical follow-up and strategies to enhance cellular antioxidants and DNA repair efficiency are important for preventing mutagenic changes caused by methylmercury exposure in autism.
Article
Environmental Sciences
Alessio Filippo Peritore, Gianluca Antonio Franco, Francesco Molinari, Alessia Arangia, Livia Interdonato, Ylenia Marino, Salvatore Cuzzocrea, Enrico Gugliandolo, Domenico Britti, Rosalia Crupi
Summary: This study revealed that chronic exposure to Vinclozolin can cause myocardial damage, cardiovascular dysfunction, and detrimental effects on cardiac enzymes and gene expression.
Article
Environmental Sciences
A. G. Romero-Calderon, T. Alvarez-Legorreta, J. Rendon von Osten, M. Gonzalez-Jauregui, J. R. Cedeno-Vazquez
Summary: Environmental pollution by metals can affect wildlife health. Some metals have an impact on the neuroendocrine stress response and can cause oxidative stress. This study investigates the association between metals and neuroendocrine stress activity, as well as biomarkers of oxidative stress in captive female Morelet's crocodiles.
ENVIRONMENTAL POLLUTION
(2022)
Article
Biochemistry & Molecular Biology
SeoYoung Kim, Hee Jin, Hang-Rhan Seo, Hae June Lee, Yun-Sil Lee
CELL DEATH AND DIFFERENTIATION
(2019)
Article
Genetics & Heredity
Hee Jin, Ga-Young Kang, Seulgi Jeon, Jin-Mo Kim, You Na Park, Jaeho Cho, Yun-Sil Lee
JOURNAL OF MOLECULAR MEDICINE-JMM
(2019)
Article
Food Science & Technology
Seoyoung Kim, Ga-Young Park, Young Jo Yoo, Ji Seong Jeong, Ki Taek Nam, Sun-Ha Jee, Kyung-Min Lim, Yun-Sil Lee
FOOD AND CHEMICAL TOXICOLOGY
(2019)
Article
Oncology
Jiwon Jung, Ji-Sun Lee, Yun-Sil Lee, Kyunglim Lee
Article
Oncology
Jee-Youn Kim, Seulgi Jeon, Young Jo Yoo, Hee Jin, Hee Yeon Won, Kyeonghee Yoon, Eun Sook Hwang, Yoon-Jin Lee, Younghwa Na, Jaeho Cho, Yun-Sil Lee
CLINICAL CANCER RESEARCH
(2019)
Correction
Chemistry, Medicinal
Gil-Im Mun, Seoyoung Kim, Eun Choi, Cha Soon Kim, Yun-Sil Lee
ARCHIVES OF PHARMACAL RESEARCH
(2019)
Article
Environmental Sciences
Bu-Yeo Kim, Minjeong Kim, Ji Seong Jeong, Sun-Ha Jee, Il-Hyun Park, Byung-Chul Lee, Sun-Ku Chung, Kyung-Min Lim, Yun-Sil Lee
ENVIRONMENTAL RESEARCH
(2019)
Review
Oncology
Seul-Ki Choi, Heejin Kam, Kye-Young Kim, Suk In Park, Yun-Sil Lee
Correction
Chemistry, Medicinal
Gil-Im Mun, Seoyoung Kim, Eun Choi, Cha Soon Kim, Yun-Sil Lee
ARCHIVES OF PHARMACAL RESEARCH
(2020)
Article
Oncology
Soo-Yeon Hwang, Seul-Ki Choi, Seung Hee Seo, Hyunji Jo, Jae-Ho Shin, Younghwa Na, Yun-Sil Lee, Youngjoo Kwon
Review
Oncology
Hee Jin, Youngjo Yoo, Younghwa Kim, Yeijin Kim, Jaeho Cho, Yun-Sil Lee
Article
Pharmacology & Pharmacy
Hawon Yoo, Seul-Ki Choi, Jaeok Lee, So Hyeon Park, You Na Park, Soo-Yeon Hwang, Jae-Ho Shin, Younghwa Na, Youngjoo Kwon, Hwa Jeong Lee, Yun-Sil Lee
Summary: Inhibition of HSP27 has been suggested as a potential strategy for cancer therapy, and the chromenone compound NA49 shows promising cancer inhibition effects in combination with anticancer drugs such as cisplatin and gefitinib in NSCLC cell lines, highlighting its potential in overcoming HSP27-mediated drug resistance.
Article
Ergonomics
Rajitha Kawshalya Mailan Arachchige Don, Seung-Cheol Hong
Summary: This study aims to understand the perspective of unskilled Sri Lankan employees in the manufacturing industry and how to utilize expatriate labor effectively in the host country workplace; the questionnaire covers basic information, perception of workplace hazards, and health and safety awareness of workers; the research reveals that language is one of the main barriers to living and working in Korea.
INTERNATIONAL JOURNAL OF OCCUPATIONAL SAFETY AND ERGONOMICS
(2022)
Article
Ergonomics
Rajitha Kawshalya Mailan Arachchige Don, Joon-Sig Jung, Yun-Jin Lee, Seung-Cheol Hong
INTERNATIONAL JOURNAL OF OCCUPATIONAL SAFETY AND ERGONOMICS
(2020)
Article
Ergonomics
Joon-Sig Jung, Jae Won Lee, Rajitha Kawshalya Mailan Arachchige Don, Duck Shin Park, Seung Cheol Hong
INTERNATIONAL JOURNAL OF OCCUPATIONAL SAFETY AND ERGONOMICS
(2019)