Chitosan leads to downregulation of YKL-40 and inflammasome activation in human macrophages

Fully Deacetylated Chitooligosaccharides Act as Efficient Glycoside Hydrolase Family 18 Chitinase Inhibitors

(2014) Lei Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Partially acetylated chitooligosaccharides bind to YKL-40 and stimulate growth of human osteoarthritic chondrocytes

(2013) Jon M. Einarsson et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Diverse pathological implications of YKL-40: Answers may lie in ‘outside-in’ signaling

(2013) Mansi Prakash et al.   CELLULAR SIGNALLING

Reduced PMA enhances the responsiveness of transfected THP-1 macrophages to polarizing stimuli

(2013) Marten B. Maeß et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Stereological analysis of subchondral angiogenesis induced by chitosan and coagulation factors in microdrilled articular cartilage defects

(2013) C. Mathieu et al.   OSTEOARTHRITIS AND CARTILAGE

Endotoxins—the Invisible Companion in Biomaterials Research

(2013) Ramona Lieder et al.   TISSUE ENGINEERING PART B-REVIEWS

Endotoxins affect bioactivity of chitosan derivatives in cultures of bone marrow-derived human mesenchymal stem cells

(2012) Ramona Lieder et al.   Acta Biomaterialia

Human YKL-39 is a pseudo-chitinase with retained chitooligosaccharide-binding properties

(2012) Marianne Schimpl et al.   BIOCHEMICAL JOURNAL

Inhibition of angiogenesis by chitooligosaccharides with specific degrees of acetylation and polymerization

(2012) Haige Wu et al.   CARBOHYDRATE POLYMERS

Chitinase 3-like-1 Promotes Streptococcus pneumoniae Killing and Augments Host Tolerance to Lung Antibacterial Responses

(2012) Charles S. Dela Cruz et al.   Cell Host & Microbe

Evaluation of CHI3L-1 and CHIT-1 Expression in Differentiated and Polarized Macrophages

(2012) Michelino Di Rosa et al.   INFLAMMATION

Chitosan oligosaccharide as potential therapy of inflammatory bowel disease: Therapeutic efficacy and possible mechanisms of action

(2012) Mohammad Yousef et al.   PHARMACOLOGICAL RESEARCH

Role of Chitin and Chitinase/Chitinase-Like Proteins in Inflammation, Tissue Remodeling, and Injury

(2011) Chun Geun Lee et al.   Annual Review of Physiology

Astrocyte and Macrophage Regulation of YKL-40 Expression and Cellular Response in Neuroinflammation

(2011) Dafna Bonneh-Barkay et al.   BRAIN PATHOLOGY

Increased chitinase expression and fungal-specific antibodies in the bronchoalveolar lavage fluid of asthmatic children

(2011) D. L. Goldman et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Attenuation of pro-inflammatory mediators in LPS-stimulated BV2 microglia by chitooligosaccharides via the MAPK signaling pathway

(2011) Ratih Pangestuti et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Chitosan but Not Chitin Activates the Inflammasome by a Mechanism Dependent upon Phagocytosis

(2011) Chelsea L. Bueter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human macrophage activation triggered by chitotriosidase-mediated chitin and chitosan degradation

(2010) Christian Gorzelanny et al.   BIOMATERIALS

Anti-Inflammatory Activity of Chitooligosaccharides in Vivo

(2010) João C. Fernandes et al.   Marine Drugs

Production of Chitooligosaccharides and Their Potential Applications in Medicine

(2010) Berit B. Aam et al.   Marine Drugs

The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages

(2010) Marc Daigneault et al.   PLoS One

YKL-40—A Protein in the Field of Translational Medicine: A Role as a Biomarker in Cancer Patients?

(2010) Nicolai A. Schultz et al.   Cancers

Novel chitin and chitosan nanofibers in biomedical applications

(2009) R. Jayakumar et al.   BIOTECHNOLOGY ADVANCES

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13–induced tissue responses and apoptosis

(2009) Chun Geun Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

YKL-40, a secreted glycoprotein, promotes tumor angiogenesis

(2009) R Shao et al.   ONCOGENE

Chitin and chitosan polymers: Chemistry, solubility and fiber formation

(2009) C.K.S. Pillai et al.   PROGRESS IN POLYMER SCIENCE

Inhibition of a family 18 chitinase by chitooligosaccharides

(2008) F. Henning Cederkvist et al.   CARBOHYDRATE POLYMERS

Evaluation of chitosan salts as non-viral gene vectors in CHO-K1 cells

(2007) W WEECHARANGSAN et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS