Conjugation of palmitic acid improves potency and longevity of siRNA delivered via endosomolytic polymer nanoparticles

Lipophilic nucleic acids — A flexible construction kit for organization and functionalization of surfaces

(2014) Matthias Schade et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Dual MMP7-Proximity-Activated and Folate Receptor-Targeted Nanoparticles for siRNA Delivery

(2014) Hongmei Li et al.   BIOMACROMOLECULES

SiRNA-phospholipid conjugates for gene and drug delivery in cancer treatment

(2014) Hongmei Liu et al.   BIOMATERIALS

Actively-targeted polyion complex micelles stabilized by cholesterol and disulfide cross-linking for systemic delivery of siRNA to solid tumors

(2014) Yusuke Oe et al.   BIOMATERIALS

Balancing Cationic and Hydrophobic Content of PEGylated siRNA Polyplexes Enhances Endosome Escape, Stability, Blood Circulation Time, and Bioactivity in Vivo

(2013) Christopher E. Nelson et al.   ACS Nano

Tunable Delivery of siRNA from a Biodegradable Scaffold to Promote Angiogenesis In Vivo

(2013) Christopher E. Nelson et al.   ADVANCED MATERIALS

Dual Responsive, Stabilized Nanoparticles for Efficient In Vivo Plasmid Delivery

(2013) Hua Wei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Differential Polymer Structure Tunes Mechanism of Cellular Uptake and Transfection Routes of Poly(β-amino ester) Polyplexes in Human Breast Cancer Cells

(2013) Jayoung Kim et al.   BIOCONJUGATE CHEMISTRY

Effective down-regulation of signal transducer and activator of transcription 3 (STAT3) by polyplexes of siRNA and lipid-substituted polyethyleneimine for sensitization of breast tumor cells to conventional chemotherapy

(2013) Arash Falamarzian et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape

(2013) Jerome Gilleron et al.   NATURE BIOTECHNOLOGY

Safety and Efficacy of RNAi Therapy for Transthyretin Amyloidosis

(2013) Teresa Coelho et al.   NEW ENGLAND JOURNAL OF MEDICINE

HIF-Prolyl Hydroxylase 2 Inhibition Enhances the Efficiency of Mesenchymal Stem Cell-Based Therapies for the Treatment of Critical Limb Ischemia

(2013) Kiave-Yune HoWangYin et al.   STEM CELLS

Amino-Modified and Lipid-Conjugated Dicer-Substrate siRNA Enhances RNAi Efficacy

(2012) Takanori Kubo et al.   BIOCONJUGATE CHEMISTRY

Controlling Mesenchymal Stem Cell Gene Expression Using Polymer-Mediated Delivery of siRNA

(2012) Danielle S. W. Benoit et al.   BIOMACROMOLECULES

Cystamine-terminated poly(beta-amino ester)s for siRNA delivery to human mesenchymal stem cells and enhancement of osteogenic differentiation

(2012) Stephany Y. Tzeng et al.   BIOMATERIALS

Polyplexes Traffic through Caveolae to the Golgi and Endoplasmic Reticulum en Route to the Nucleus

(2012) Meghan J. Reilly et al.   MOLECULAR PHARMACEUTICS

Harnessing a Physiologic Mechanism for siRNA Delivery With Mimetic Lipoprotein Particles

(2012) Tomoko Nakayama et al.   MOLECULAR THERAPY

Multivalent Cyclic RGD Conjugates for Targeted Delivery of Small Interfering RNA

(2011) Md. Rowshon Alam et al.   BIOCONJUGATE CHEMISTRY

Sustained local delivery of siRNA from an injectable scaffold

(2011) Christopher E. Nelson et al.   BIOMATERIALS

Progress Toward In Vivo Use of siRNAs-II

(2011) Garrett R Rettig et al.   MOLECULAR THERAPY

Delivery of siRNA Therapeutics: Barriers and Carriers

(2010) Jie Wang et al.   AAPS Journal

Polyplex micelles prepared from ω-cholesteryl PEG-polycation block copolymers for systemic gene delivery

(2010) Makoto Oba et al.   BIOMATERIALS

Lipidic Systems for In Vivo siRNA Delivery

(2009) Sherry Y. Wu et al.   AAPS Journal

Lipid-based systemic delivery of siRNA

(2009) Yu-Cheng Tseng et al.   ADVANCED DRUG DELIVERY REVIEWS

Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice

(2009) Xing Shen et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Development of a novel endosomolytic diblock copolymer for siRNA delivery

(2008) Anthony J. Convertine et al.   JOURNAL OF CONTROLLED RELEASE

Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-Tocopherol

(2008) Kazutaka Nishina et al.   MOLECULAR THERAPY

Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

(2008) M. Frank-Kamenetsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA