Role of zinc and copper ions in the pathogenetic mechanisms of Alzheimer’s and Parkinson’s diseases

Inhibition of Mn2+-induced error-prone DNA synthesis with Cd2+ and Zn2+

(2013) L. V. Gening et al.   BIOCHEMISTRY-MOSCOW

High precision isotope measurements reveal poor control of copper metabolism in Parkinsonism

(2013) F. Larner et al.   Metallomics

The missing link in the amyloid cascade of Alzheimer’s disease – Metal ions

(2013) Ann Tiiman et al.   NEUROCHEMISTRY INTERNATIONAL

Role of the P-Type ATPases, ATP7A and ATP7B in brain copper homeostasis

(2013) Jonathon Telianidis et al.   Frontiers in Aging Neuroscience

Mitochondrion-Derived Reactive Oxygen Species Lead to Enhanced Amyloid Beta Formation

(2012) Kristina Leuner et al.   ANTIOXIDANTS & REDOX SIGNALING

Chelating Agents for Neurodegenerative Diseases

(2012) R. J. Ward et al.   CURRENT MEDICINAL CHEMISTRY

Designing drugs with multi-target activity: the next step in the treatment of neurodegenerative disorders

(2012) Werner J Geldenhuys et al.   Expert Opinion on Drug Discovery

Clinical utility of neuroprotective agents in neurodegenerative diseases: current status of drug development for Alzheimer's, Parkinson's and Huntington's diseases, and amyotrophic lateral sclerosis

(2012) Petra Dunkel et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Metallostasis in Alzheimer's disease

(2012) Scott Ayton et al.   FREE RADICAL BIOLOGY AND MEDICINE

Copper toxicity in Alzheimer's disease: Cognitive loss from ingestion of inorganic copper

(2012) George J. Brewer   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Metal dyshomeostasis and oxidative stress in Alzheimer’s disease

(2012) Mark A. Greenough et al.   NEUROCHEMISTRY INTERNATIONAL

Mitochondrial Inhibitor Models of Huntington’s Disease and Parkinson’s Disease Induce Zinc Accumulation and Are Attenuated by Inhibition of Zinc Neurotoxicity in vitro or in vivo

(2012) Christian T. Sheline et al.   Neurodegenerative Diseases

Zinc diet and Alzheimer's disease: a systematic review

(2012) Martin Loef et al.   NUTRITIONAL NEUROSCIENCE

The Zinc Dyshomeostasis Hypothesis of Alzheimer's Disease

(2012) Travis J. A. Craddock et al.   PLoS One

In vivo injected mitochondria-targeted plastoquinone antioxidant SkQR1 prevents β-amyloid-induced decay of long-term potentiation in rat hippocampal slices

(2011) N. A. Kapay et al.   BIOCHEMISTRY-MOSCOW

Transition metal abnormalities in progressive dementias

(2011) Hiroyasu Akatsu et al.   BIOMETALS

Glucose starvation stimulates Zn2+ toxicity in cultures of cerebellar granule neurons

(2011) Nickolay K. Isaev et al.   BRAIN RESEARCH BULLETIN

Mitochondria as a Therapeutic Target for Aging and Neurodegenerative Diseases

(2011) P. H. Reddy et al.   Current Alzheimer Research

Redox activity of α-synuclein–Cu is silenced by Zn7-metallothionein-3

(2011) Gabriele Meloni et al.   FREE RADICAL BIOLOGY AND MEDICINE

Zn2+’s Ability to Alter the Distribution of Cu2+among the Available Binding Sites of Aβ(1–16)-Polyethylenglycol-ylated Peptide: Implications in Alzheimer’s Disease

(2011) Chiara A. Damante et al.   INORGANIC CHEMISTRY

Metallothionein protein evolution: a miniassay

(2011) Mercè Capdevila et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Amyloid  -Induced Impairments in Hippocampal Synaptic Plasticity Are Rescued by Decreasing Mitochondrial Superoxide

(2011) T. Ma et al.   JOURNAL OF NEUROSCIENCE

Patterns of levels of biological metals in CSF differ among neurodegenerative diseases

(2011) Isao Hozumi et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Subclinical Zinc Deficiency in Alzheimer’s Disease and Parkinson’s Disease

(2010) George J. Brewer et al.   American Journal of Alzheimers Disease and Other Dementias

Zinc supplement greatly improves the condition of parkin mutant Drosophila

(2010) Nidhi Saini et al.   BIOLOGICAL CHEMISTRY

Acidosis-Induced Zinc-Dependent Death of Cultured Cerebellar Granule Neurons

(2010) Nikolay K. Isaev et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Copper(ii) complexes of hybrid hydroxyquinoline-thiosemicarbazone ligands: GSK3β inhibition due to intracellular delivery of copper

(2010) James L. Hickey et al.   DALTON TRANSACTIONS

Copper binding regulates intracellular alpha-synuclein localisation, aggregation and toxicity

(2010) Xiaoyan Wang et al.   JOURNAL OF NEUROCHEMISTRY

Cognitive Loss in Zinc Transporter-3 Knock-Out Mice: A Phenocopy for the Synaptic and Memory Deficits of Alzheimer's Disease?

(2010) P. A. Adlard et al.   JOURNAL OF NEUROSCIENCE

Metals, oxidative stress and neurodegenerative disorders

(2010) Klaudia Jomova et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Metallomic Profiling and Linkage Map Analysis of Early Parkinson's Disease: A New Insight to Aluminum Marker for the Possible Diagnosis

(2010) Shiek S. S. J. Ahmed et al.   PLoS One

The Native Copper- and Zinc- Binding Protein Metallothionein Blocks Copper-Mediated Aβ Aggregation and Toxicity in Rat Cortical Neurons

(2010) Roger S. Chung et al.   PLoS One

Serum zinc is decreased in Alzheimer’s disease and serum arsenic correlates positively with cognitive ability

(2009) Larry Baum et al.   BIOMETALS

Cytosolic labile zinc accumulation in degenerating dopaminergic neurons of mouse brain after MPTP treatment

(2009) Joo-Yong Lee et al.   BRAIN RESEARCH

Identification of a Novel Zn2+-binding Domain in the Autosomal Recessive Juvenile Parkinson-related E3 Ligase Parkin

(2009) Ventzislava A. Hristova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Low Micromolar Zinc Accelerates the Fibrillization of Human Tau via Bridging of Cys-291 and Cys-322

(2009) Zhong-Ying Mo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic copper exposure exacerbates both amyloid and tau pathology and selectively dysregulates cdk5 in a mouse model of AD

(2009) Masashi Kitazawa et al.   JOURNAL OF NEUROCHEMISTRY

Systemic Oxidative Stress Associated with the Neurological Diseases of Aging

(2009) Jorge A. Serra et al.   NEUROCHEMICAL RESEARCH

Increasing Cu bioavailability inhibits A  oligomers and tau phosphorylation

(2009) P. J. Crouch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zinc: The brain's dark horse

(2009) Byron K.Y. Bitanihirwe et al.   SYNAPSE

Metals in Alzheimer's and Parkinson's Diseases

(2008) Kevin J Barnham et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Intake of copper has no effect on cognition in patients with mild Alzheimer’s disease: a pilot phase 2 clinical trial

(2008) Holger Kessler et al.   JOURNAL OF NEURAL TRANSMISSION