How does the body know how old it is? Introducing the epigenetic clock hypothesis

Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice

(2016) Yuliya V. Dubrovsky et al.   Aging-US

Studies that shed new light on aging

(2013) H. L. Katcher   BIOCHEMISTRY-MOSCOW

Telomere biology: Cancer firewall or aging clock?

(2013) J. J. Mitteldorf   BIOCHEMISTRY-MOSCOW

Adaptive aging in the context of evolutionary theory

(2012) J. J. Mitteldorf   BIOCHEMISTRY-MOSCOW

Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer

(2012) Bruno Bernardes de Jesus et al.   EMBO Molecular Medicine

Distinct DNA methylomes of newborns and centenarians

(2012) H. Heyn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of DNA Methylation in Aging, Rejuvenation, and Age-Related Disease

(2012) Adiv A. Johnson et al.   REJUVENATION RESEARCH

Global DNA methylation in old subjects is correlated with frailty

(2011) Dina Bellizzi et al.   AGE

The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence

(2011) Bruno Bernardes de Jesus et al.   AGING CELL

Insufficient DNA methylation affects healthy aging and promotes age-related health problems

(2011) Liang Liu et al.   Clinical Epigenetics

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

(2010) Mariela Jaskelioff et al.   NATURE

Enhanced one-carbon flux towards DNA methylation: Effect of dietary methyl supplements against γ-radiation-induced epigenetic modifications

(2009) Vipen Batra et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Transgenerational Epigenetic Inheritance: Prevalence, Mechanisms, and Implications for the Study of Heredity and Evolution

(2009) Eva Jablonka et al.   QUARTERLY REVIEW OF BIOLOGY