Journal
BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION
Volume 38, Issue 3, Pages 134-140Publisher
WILEY
DOI: 10.1002/bmb.20406
Keywords
mitochondria; cellular biology; molecular biology; molecular visualization; textbook diagrams; energy metabolism; apoptosis; programmed cell death; endosymbiont hypothesis
Funding
- RCSB PDB [NSF DBI 03-12718]
- National Science Foundation [DUE 06-18688]
- Fondation Scientifique Fourmentin-Guilbert
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Diverse biological data may be used to create illustrations of molecules in their cellular context. I describe the scientific results that support a recent textbook illustration of a mitochondrion. The image magnifies a portion of the mitochondrion by one million times, showing the location and form of membranes and individual macromolecules, revealing the molecular basis of its role in energy metabolism and apoptosis. Results from biochemistry, electron microscopy, and X-ray crystallography were used to create the image.
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