Mechanisms of small-molecule binding to intrinsically disordered proteins: Figure 1

Effects of Ligands on Unfolding of the Amyloid β-Peptide Central Helix: Mechanistic Insights from Molecular Dynamics Simulations

(2012) Mika Ito et al.   PLoS One

The Impact of Small Molecule Binding on the Energy Landscape of the Intrinsically Disordered Protein C-Myc

(2012) Julien Michel et al.   PLoS One

Intrinsically disordered proteins from A to Z

(2011) Vladimir N. Uversky   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Disordered Binding of Small Molecules to Aβ(12–28)

(2011) Marino Convertino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding of Inositol Stereoisomers To Model Amyloidogenic Peptides

(2011) Grace Li et al.   JOURNAL OF PHYSICAL CHEMISTRY B

The p53-MDM2/MDMX axis – A chemotype perspective

(2011) Kareem Khoury et al.   MedChemComm

Understanding protein non-folding

(2010) Vladimir N. Uversky et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Multitude of binding modes attainable by intrinsically disordered proteins: a portrait gallery of disorder-based complexes

(2010) Vladimir N. Uversky   CHEMICAL SOCIETY REVIEWS

The Development of New Therapeutics for Alzheimer's Disease

(2010) M D Carter et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Intrinsically disordered proteins are potential drug targets

(2010) Steven J Metallo   CURRENT OPINION IN CHEMICAL BIOLOGY

Tau protein and tau aggregation inhibitors

(2010) Bruno Bulic et al.   NEUROPHARMACOLOGY

On the Mechanism of Nonspecific Inhibitors of Protein Aggregation: Dissecting the Interactions of α-Synuclein with Congo Red and Lacmoid

(2009) Christofer Lendel et al.   BIOCHEMISTRY

Aβ aggregation and possible implications in Alzheimer's disease pathogenesis

(2009) Prashant R. Bharadwaj et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Multiple Independent Binding Sites for Small-Molecule Inhibitors on the Oncoprotein c-Myc

(2009) Dalia I. Hammoudeh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

O1-06-04: Methylthioninium chloride (MTC) acts as a Tau aggregation inhibitor (TAI) in a cellular model and reverses Tau pathology in transgenic mouse models of Alzheimer's disease

(2008) Charles Harrington et al.   Alzheimers & Dementia

Intrinsically Disordered Proteins in Human Diseases: Introducing the D2 Concept

(2008) Vladimir N. Uversky et al.   Annual Review of Biophysics

Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy

(2008) Sanjeev Shangary et al.   Annual Review of Pharmacology and Toxicology

Small-molecule perturbation of competing interactions between c-Myc and Max

(2008) Ariele Viacava Follis et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structural Rationale for the Coupled Binding and Unfolding of the c-Myc Oncoprotein by Small Molecules

(2008) Ariele Viacava Follis et al.   CHEMISTRY & BIOLOGY

Inhibition of α-Synuclein Fibrillization by Dopamine Is Mediated by Interactions with Five C-Terminal Residues and with E83 in the NAC Region

(2008) Fernando E. Herrera et al.   PLoS One

TOP-IDP-Scale: A New Amino Acid Scale Measuring Propensity for Intrinsic Disorder

(2008) Andrew Campen et al.   PROTEIN AND PEPTIDE LETTERS