Disordered Binding of Small Molecules to Aβ(12–28)

The Amyloid-Congo Red Interface at Atomic Resolution

(2011) Anne K. Schütz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mutations That Replace Aromatic Side Chains Promote Aggregation of the Alzheimer’s Aβ Peptide

(2011) Anne H. Armstrong et al.   BIOCHEMISTRY

Resveratrol Inhibits the Formation of Multiple-Layered β-Sheet Oligomers of the Human Islet Amyloid Polypeptide Segment 22–27

(2011) Ping Jiang et al.   BIOPHYSICAL JOURNAL

Naproxen Interferes with the Assembly of Aβ Oligomers Implicated in Alzheimer's Disease

(2011) Seongwon Kim et al.   BIOPHYSICAL JOURNAL

Coarse-grained models for protein aggregation

(2011) Chun Wu et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Inhibition and disaggregation of α-synuclein oligomers by natural polyphenolic compounds

(2011) Mario Caruana et al.   FEBS LETTERS

Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation

(2011) Stuart A. Sievers et al.   NATURE

Towards a Pharmacophore for Amyloid

(2011) Meytal Landau et al.   PLOS BIOLOGY

Mapping Conformational Ensembles of Aβ Oligomers in Molecular Dynamics Simulations

(2010) Seongwon Kim et al.   BIOPHYSICAL JOURNAL

Beta Amyloid Aggregation Inhibitors: Small Molecules as Candidate Drugs for Therapy of Alzheimers Disease

(2010) F. Re et al.   CURRENT MEDICINAL CHEMISTRY

Wordom: A user-friendly program for the analysis of molecular structures, trajectories, and free energy surfaces

(2010) Michele Seeber et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Quantitative structure–activity relationship analysis of β-amyloid aggregation inhibitors

(2010) Shiri Stempler et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Micelle-Like Architecture of the Monomer Ensemble of Alzheimer’s Amyloid-β Peptide in Aqueous Solution and Its Implications for Aβ Aggregation

(2010) Andreas Vitalis et al.   JOURNAL OF MOLECULAR BIOLOGY

The Anti-Parkinsonian Drug Selegiline Delays the Nucleation Phase of α-Synuclein Aggregation Leading to the Formation of Nontoxic Species

(2010) Carolina A. Braga et al.   JOURNAL OF MOLECULAR BIOLOGY

Nonsteroidal Anti-inflammatory Drug Naproxen Destabilizes Aβ Amyloid Fibrils: A Molecular Dynamics Investigation

(2010) Takako Takeda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

The inhibitory effect of pyrroloquinoline quinone on the amyloid formation and cytotoxicity of truncated alpha-synuclein

(2010) Jihoon Kim et al.   Molecular Neurodegeneration

Modulation of Alpha-Synuclein Aggregation by Dopamine Analogs

(2010) Diane Latawiec et al.   PLoS One

Complete Phenotypic Recovery of an Alzheimer's Disease Model by a Quinone-Tryptophan Hybrid Aggregation Inhibitor

(2010) Roni Scherzer-Attali et al.   PLoS One

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

(2010) Jan Bieschke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induced fit, conformational selection and independent dynamic segments: an extended view of binding events

(2010) Peter Csermely et al.   TRENDS IN BIOCHEMICAL SCIENCES

Ellagic acid promotes Aβ42 fibrillization and inhibits Aβ42-induced neurotoxicity

(2009) Ying Feng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Converse modulation of toxic α-synuclein oligomers in living cells by N′-benzylidene-benzohydrazide derivates and ferric iron

(2009) Andreas S. Hillmer et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Unfoldomics of human diseases: linking protein intrinsic disorder with diseases

(2009) Vladimir N Uversky et al.   BMC GENOMICS

Biophysical characterization of intrinsically disordered proteins

(2009) David Eliezer   CURRENT OPINION IN STRUCTURAL BIOLOGY

Linking folding and binding

(2009) Peter E Wright et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Small molecule inhibitors of Aβ-aggregation and neurotoxicity

(2009) Cheryl A. Hawkes et al.   DRUG DEVELOPMENT RESEARCH

Aβ aggregation and possible implications in Alzheimer's disease pathogenesis

(2009) Prashant R. Bharadwaj et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

At Low Concentrations, 3,4-Dihydroxyphenylacetic Acid (DOPAC) Binds Non-Covalently to α-Synuclein and Prevents Its Fibrillation

(2009) Wenbo Zhou et al.   JOURNAL OF MOLECULAR BIOLOGY

Elucidating the Mechanism of Lipid Membrane-Induced IAPP Fibrillogenesis and Its Inhibition by the Red Wine Compound Resveratrol: A Synchrotron X-ray Reflectivity Study

(2009) Florian Evers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Curcumin inhibits aggregation of α-synuclein

(2008) Neeraj Pandey et al.   ACTA NEUROPATHOLOGICA

Small-Molecule Inhibitors of Islet Amyloid Polypeptide Fibril Formation

(2008) Rajesh Mishra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cognitive-Performance Recovery of Alzheimer's Disease Model Mice by Modulation of Early Soluble Amyloidal Assemblies

(2008) Anat Frydman-Marom et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intrinsically Disordered Proteins in Human Diseases: Introducing the D2 Concept

(2008) Vladimir N. Uversky et al.   Annual Review of Biophysics

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Structures and Free-Energy Landscapes of the Wild Type and Mutants of the Aβ21–30 Peptide Are Determined by an Interplay between Intrapeptide Electrostatic and Hydrophobic Interactions

(2008) Bogdan Tarus et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Characteristics of α-Synuclein Oligomers Stabilized by the Flavonoid Baicalein

(2008) Dong-Pyo Hong et al.   JOURNAL OF MOLECULAR BIOLOGY

Polyphenols as Potential Inhibitors of Amyloid Aggregation and Toxicity:Possible Significance to Alzheimers Disease

(2008) S. Bastianetto et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Small-molecule aggregates inhibit amyloid polymerization

(2008) Brian Y Feng et al.   Nature Chemical Biology

Role of the familial Dutch mutation E22Q in the folding and aggregation of the 15-28 fragment of the Alzheimer amyloid-  protein

(2008) A. Baumketner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting the early steps of Aβ16-22 protofibril disassembly by N-methylated inhibitors: A numerical study

(2008) Yassmine Chebaro et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A polymer physics perspective on driving forces and mechanisms for protein aggregation

(2007) Rohit V. Pappu et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

FACTS: Fast analytical continuum treatment of solvation

(2007) Urs Haberthür et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

On the nucleation of amyloid β-protein monomer folding

(2005) Noel D. Lazo et al.   PROTEIN SCIENCE