Npas4 Transcription Factor Expression Is Regulated by Calcium Signaling Pathways and Prevents Tacrolimus-induced Cytotoxicity in Pancreatic Beta Cells

All-encomPASsing regulation of β-cells: PAS domain proteins in β-cell dysfunction and diabetes

(2015) Paul V. Sabatini et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Cathepsin Inhibition-Induced Lysosomal Dysfunction Enhances Pancreatic Beta-Cell Apoptosis in High Glucose

(2015) Minjeong Jung et al.   PLoS One

Calcium signaling in pancreatic β-cells in health and in Type 2 diabetes

(2014) Patrick Gilon et al.   CELL CALCIUM

Palmitate Induces mRNA Translation and Increases ER Protein Load in Islet  -Cells via Activation of the Mammalian Target of Rapamycin Pathway

(2014) M. Hatanaka et al.   DIABETES

Inhibition of Pancreatic β-Cell Ca2+/Calmodulin-dependent Protein Kinase II Reduces Glucose-stimulated Calcium Influx and Insulin Secretion, Impairing Glucose Tolerance

(2014) Prasanna K. Dadi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Infusion of growth hormone into the hippocampus induces molecular and behavioral responses in mice

(2014) Paitoon Srimontri et al.   EXPERIMENTAL BRAIN RESEARCH

Metabolic memory of ß-cells controls insulin secretion and is mediated by CaMKIIa

(2014) Gustavo Jorge dos Santos et al.   Molecular Metabolism

CREB mediates the insulinotropic and anti-apoptotic effects of GLP-1 signaling in adult mouse β-cells

(2014) Soona Shin et al.   Molecular Metabolism

Regulation of the neuronal transcription factor NPAS4 by REST and microRNAs

(2013) David C. Bersten et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Npas4 Is a Novel Activity–Regulated Cytoprotective Factor in Pancreatic β-Cells

(2013) Paul V. Sabatini et al.   DIABETES

Effects of CaMKII-Mediated Phosphorylation of Ryanodine Receptor Type 2 on Islet Calcium Handling, Insulin Secretion, and Glucose Tolerance

(2013) Sayali S. Dixit et al.   PLoS One

Tacrolimus Inhibits the Revascularization of Isolated Pancreatic Islets

(2013) Ryuichi Nishimura et al.   PLoS One

Is Dynamic Autocrine Insulin Signaling Possible? A Mathematical Model Predicts Picomolar Concentrations of Extracellular Monomeric Insulin within Human Pancreatic Islets

(2013) Minghu Wang et al.   PLoS One

New-Onset Diabetes After Transplantation: Assessment of Risk Factors and Clinical Outcomes

(2013) P. Cotovio et al.   TRANSPLANTATION PROCEEDINGS

Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals

(2013) Jing Qiu et al.   Nature Communications

The impact of Ca2+/calmodulin-dependent protein kinase II on insulin gene expression in MIN6 cells

(2012) Mihoshi Suefuji et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

(2012) Chutima Talchai et al.   CELL

Role of AMPK in pancreatic beta cell function

(2012) Accalia Fu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The CaMK4/CREB/IRS-2 Cascade Stimulates Proliferation and Inhibits Apoptosis of β-Cells

(2012) Bo Liu et al.   PLoS One

Regulation of calcium in pancreatic α- and β-cells in health and disease

(2011) Patrik Rorsman et al.   CELL CALCIUM

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

Risk factors and consequences of post-transplant diabetes mellitus

(2010) Meltem Sezis Demirci et al.   CLINICAL TRANSPLANTATION

Calcineurin Signaling Regulates Human Islet β-Cell Survival

(2010) Scott A. Soleimanpour et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Different Effects of FK506, Rapamycin, and Mycophenolate Mofetil on Glucose-Stimulated Insulin Release and Apoptosis in Human Islets

(2009) James D. Johnson et al.   CELL TRANSPLANTATION

Meta-regulation: microRNA regulation of glucose and lipid metabolism

(2009) Francis C. Lynn   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Nuclear Calcium Signaling Controls Expression of a Large Gene Pool: Identification of a Gene Program for Acquired Neuroprotection Induced by Synaptic Activity

(2009) Sheng-Jia Zhang et al.   PLoS Genetics

Emerging roles for the ubiquitin-proteasome system and autophagy in pancreatic β-cells

(2008) Taila Hartley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Insulin Signaling in the Pancreatic β-Cell

(2008) Ingo B. Leibiger et al.   Annual Review of Nutrition

Dynamic regulation of bHLH-PAS-type transcription factor NXF gene expression and neurotrophin dependent induction of the transcriptional control activity

(2008) Norihisa Ooe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The importance of RNA binding proteins in preproinsulin mRNA stability

(2008) R FRED et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Commentary: The Year in Basic Science: Calmodulin Kinase Cascades

(2008) Anthony R. Means   MOLECULAR ENDOCRINOLOGY

Activity-dependent regulation of inhibitory synapse development by Npas4

(2008) Yingxi Lin et al.   NATURE

Growth factor control of pancreatic islet regeneration and function

(2008) Anke Assmann et al.   PEDIATRIC DIABETES