Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals

Role of Mitochondrial Ca2+ in the Regulation of Cellular Energetics

(2012) Brian Glancy et al.   BIOCHEMISTRY

The interplay of mitochondria with calcium: An historical appraisal

(2012) Ernesto Carafoli   CELL CALCIUM

Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration

(2012) P Rodriguez-Rodriguez et al.   CELL DEATH AND DIFFERENTIATION

PGC-1  Negatively Regulates Extrasynaptic NMDAR Activity and Excitotoxicity

(2012) C. Puddifoot et al.   JOURNAL OF NEUROSCIENCE

Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain

(2012) Douglas J. Cook et al.   NATURE

MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism

(2012) Karthik Mallilankaraman et al.   NATURE CELL BIOLOGY

The Subtype of GluN2 C-terminal Domain Determines the Response to Excitotoxic Insults

(2012) Marc-André Martel et al.   NEURON

Mitochondria, calcium-dependent neuronal death and neurodegenerative disease

(2012) Michael R. Duchen   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Differential mitochondrial calcium responses in different cell types detected with a mitochondrial calcium fluorescent indicator, mito-GCaMP2

(2011) Min Chen et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

A Signaling Cascade of Nuclear Calcium-CREB-ATF3 Activated by Synaptic NMDA Receptors Defines a Gene Repression Module That Protects against Extrasynaptic NMDA Receptor-Induced Neuronal Cell Death and Ischemic Brain Damage

(2011) S.-J. Zhang et al.   JOURNAL OF NEUROSCIENCE

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

(2011) Joshua M. Baughman et al.   NATURE

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

(2011) Diego De Stefani et al.   NATURE

Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death

(2011) Shaida A Andrabi et al.   NATURE MEDICINE

Calcium-dependent mitochondrial function and dysfunction in neurons

(2010) Natalia B. Pivovarova et al.   FEBS Journal

Synaptic Activity and Nuclear Calcium Signaling Protect Hippocampal Neurons from Death Signal-associated Nuclear Translocation of FoxO3a Induced by ExtrasynapticN-Methyl-d-aspartate Receptors

(2010) Oliver Dick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MICU1 encodes a mitochondrial EF hand protein required for Ca2+ uptake

(2010) Fabiana Perocchi et al.   NATURE

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Glutamate receptors, neurotoxicity and neurodegeneration

(2010) Anthony Lau et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Mitochondrial calcium function and dysfunction in the central nervous system

(2009) David G. Nicholls   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Synaptic Activity-Mediated Suppression of p53 and Induction of Nuclear Calcium-Regulated Neuroprotective Genes Promote Survival through Inhibition of Mitochondrial Permeability Transition

(2009) D. Lau et al.   JOURNAL OF NEUROSCIENCE

Genome-Wide RNAi Screen Identifies Letm1 as a Mitochondrial Ca2+/H+ Antiporter

(2009) D. Jiang et al.   SCIENCE

Nuclear Calcium Signaling Controls Expression of a Large Gene Pool: Identification of a Gene Program for Acquired Neuroprotection Induced by Synaptic Activity

(2009) Sheng-Jia Zhang et al.   PLoS Genetics

Mechanisms underlying the loss of mitochondrial membrane potential in glutamate excitotoxicity

(2008) Andrey Y. Abramov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Elevated Synaptic Activity Preconditions Neurons against anin VitroModel of Ischemia

(2008) Joseph S. Tauskela et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Specific Targeting of Pro-Death NMDA Receptor Signals with Differing Reliance on the NR2B PDZ Ligand

(2008) F. X. Soriano et al.   JOURNAL OF NEUROSCIENCE

Activity-dependent regulation of inhibitory synapse development by Npas4

(2008) Yingxi Lin et al.   NATURE

Characterization and Subcellular Targeting of GCaMP-Type Genetically-Encoded Calcium Indicators

(2008) Tianyi Mao et al.   PLoS One