Running on time: the role of circadian clocks in the musculoskeletal system

Glucocorticoids mediate circadian timing in peripheral osteoclasts resulting in the circadian expression rhythm of osteoclast-related genes

(2014) Yuko Fujihara et al.   BONE

Lentiviral Delivery of PPARγ shRNA Alters the Balance of Osteogenesis and Adipogenesis, Improving Bone Microarchitecture

(2014) Aaron W. James et al.   TISSUE ENGINEERING PART A

Gremlin-2 is a BMP antagonist that is regulated by the circadian clock

(2014) Ching-Yan Chloé Yeung et al.   Scientific Reports

Impact of fasting on the rhythmic expression of myogenic and metabolic factors in skeletal muscle of adult mice

(2013) T. Shavlakadze et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Circadian Clock in Murine Chondrocytes Regulates Genes Controlling Key Aspects of Cartilage Homeostasis

(2013) Nicole Gossan et al.   ARTHRITIS AND RHEUMATISM

Different circadian expression of major matrix-related genes in various types of cartilage: modulation by light–dark conditions

(2013) Kiyomasa K. Honda et al.   JOURNAL OF BIOCHEMISTRY

Brain and muscle Arnt-like 1 is a key regulator of myogenesis

(2013) S. Chatterjee et al.   JOURNAL OF CELL SCIENCE

Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

(2013) Estelle Woldt et al.   NATURE MEDICINE

Prolonged Bioluminescence Monitoring in Mouse Ex Vivo Bone Culture Revealed Persistent Circadian Rhythms in Articular Cartilages and Growth Plates

(2013) Naoki Okubo et al.   PLoS One

Membrane Localization of Membrane Type 1 Matrix Metalloproteinase by CD44 Regulates the Activation of Pro-Matrix Metalloproteinase 9 in Osteoclasts

(2013) Meenakshi A. Chellaiah et al.   Biomed Research International

Comparison of β-Adrenergic and Glucocorticoid Signaling on Clock Gene and Osteoblast-Related Gene Expressions in Human Osteoblast

(2012) Shintaro Komoto et al.   CHRONOBIOLOGY INTERNATIONAL

Clock Genes Influence Gene Expression in Growth Plate and Endochondral Ossification in Mice

(2012) Takeshi Takarada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Scheduled Exercise Phase Shifts the Circadian Clock in Skeletal Muscle

(2012) GRETCHEN WOLFF et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

A non-canonical E-box within the MyoD core enhancer is necessary for circadian expression in skeletal muscle

(2012) Xiping Zhang et al.   NUCLEIC ACIDS RESEARCH

An essential role for the circadian-regulated gene Nocturnin in osteogenesis: the importance of local timekeeping in skeletal homeostasis

(2011) Anyonya R. Guntur et al.   Annals of the New York Academy of Sciences

Disorders of Bone Remodeling

(2011) Xu Feng et al.   Annual Review of Pathology-Mechanisms of Disease

ADAMTS-4 and ADAMTS-5: Key enzymes in osteoarthritis

(2011) Priyanka Verma et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The circadian molecular clock creates epidermal stem cell heterogeneity

(2011) Peggy Janich et al.   NATURE

The Mammalian Circadian Timing System: Organization and Coordination of Central and Peripheral Clocks

(2010) Charna Dibner et al.   Annual Review of Physiology

THE INFLUENCE OF CIRCADIAN PHASE AND PRIOR WAKE ON NEUROMUSCULAR FUNCTION

(2010) Charli Sargent et al.   CHRONOBIOLOGY INTERNATIONAL

Per-1 is a specific clock gene regulated by parathyroid hormone (PTH) signaling in osteoblasts and is functional for the transcriptional events induced by PTH

(2010) Ryo Hanyu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

(2010) Biliana Marcheva et al.   NATURE

The Clock Genes Period 2 and Cryptochrome 2 Differentially Balance Bone Formation

(2010) Erik Maronde et al.   PLoS One

CLOCK and BMAL1 regulate MyoD and are necessary for maintenance of skeletal muscle phenotype and function

(2010) J. L. Andrews et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A circadian-regulated gene, Nocturnin, promotes adipogenesis by stimulating PPAR-  nuclear translocation

(2010) M. Kawai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MT1-MMP and Type II Collagen Specify Skeletal Stem Cells and Their Bone and Cartilage Progeny

(2009) Ludmila Szabova et al.   JOURNAL OF BONE AND MINERAL RESEARCH

PPARγ2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells

(2009) Keith R. Shockley et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cartilage in normal and osteoarthritis conditions

(2008) Johanne Martel-Pelletier et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Collagen fibrillogenesis: fibronectin, integrins, and minor collagens as organizers and nucleators

(2008) Karl E Kadler et al.   CURRENT OPINION IN CELL BIOLOGY

Scheduled exposures to a novel environment with a running-wheel differentially accelerate re-entrainment of mice peripheral clocks to new light–dark cycles

(2008) Yujiro Yamanaka et al.   GENES TO CELLS

CLOCK/BMAL1 regulates human nocturnin transcription through binding to the E-box of nocturnin promoter

(2008) Ran Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The genetics of mammalian circadian order and disorder: implications for physiology and disease

(2008) Joseph S. Takahashi et al.   NATURE REVIEWS GENETICS

Multifunctional deadenylase complexes diversify mRNA control

(2008) Aaron C. Goldstrohm et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Signaling in Muscle Atrophy and Hypertrophy

(2008) Marco Sandri   PHYSIOLOGY

Physiological significance of a peripheral tissue circadian clock

(2008) K. A. Lamia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of Gene Regulatory Networks in the Mammalian Circadian Rhythm

(2008) Jun Yan et al.   PLoS Computational Biology